Identity
HGNC
LOCATION
Xq28
LOCUSID
ALIAS
HIBBJ46,PFD3,PFDN3,VBP-1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7411
MIM: 300133
HGNC: 12662
Ensembl: ENSG00000155959
Variants:
dbSNP: 7411
ClinVar: 7411
TCGA: ENSG00000155959
COSMIC: VBP1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000155959 | ENST00000286428 | P61758 |
| ENSG00000155959 | ENST00000535916 | P61758 |
| ENSG00000155959 | ENST00000625964 | P61758 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38700744 | 2024 | VBP1 promotes tumor proliferation as a part of the hypoxia-related signature in esophageal squamous cell carcinoma. | 0 |
| 38700744 | 2024 | VBP1 promotes tumor proliferation as a part of the hypoxia-related signature in esophageal squamous cell carcinoma. | 0 |
| 32989053 | 2020 | VBP1 modulates Wnt/β-catenin signaling by mediating the stability of the transcription factors TCF/LEFs. | 8 |
| 33137104 | 2020 | The prefoldin complex stabilizes the von Hippel-Lindau protein against aggregation and degradation. | 5 |
| 32989053 | 2020 | VBP1 modulates Wnt/β-catenin signaling by mediating the stability of the transcription factors TCF/LEFs. | 8 |
| 33137104 | 2020 | The prefoldin complex stabilizes the von Hippel-Lindau protein against aggregation and degradation. | 5 |
| 29121446 | 2018 | VBP1 represses cancer metastasis by enhancing HIF-1α degradation induced by pVHL. | 24 |
| 29121446 | 2018 | VBP1 represses cancer metastasis by enhancing HIF-1α degradation induced by pVHL. | 24 |
| 23964080 | 2013 | VBP1 facilitates proteasome and autophagy-mediated degradation of MutS homologue hMSH4. | 18 |
| 23964080 | 2013 | VBP1 facilitates proteasome and autophagy-mediated degradation of MutS homologue hMSH4. | 18 |
| 17698809 | 2007 | von Hippel Lindau binding protein 1-mediated degradation of integrase affects HIV-1 gene expression at a postintegration step. | 48 |
| 17698809 | 2007 | von Hippel Lindau binding protein 1-mediated degradation of integrase affects HIV-1 gene expression at a postintegration step. | 48 |
| 12613020 | 2003 | [Identification of a factor, which binds to HIF-1 alpha and regulates the function of HIF-1 alpha]. | 0 |
| 12613020 | 2003 | [Identification of a factor, which binds to HIF-1 alpha and regulates the function of HIF-1 alpha]. | 0 |
Citation
Dessen P
VBP1 (VHL binding protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42783/vbp1
