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VCAM1 (vascular cell adhesion molecule 1)

Identity

Alias_symbol (synonym)CD106
Other aliasINCAM-100
HGNC (Hugo) VCAM1
LocusID (NCBI) 7412
Atlas_Id 42784
Location 1p21.2  [Link to chromosome band 1p21]
Location_base_pair Starts at 100719640 and ends at 100739046 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
VPS37A (8p22) / VCAM1 (1p21.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)VCAM1   12663
Cards
Entrez_Gene (NCBI)VCAM1  7412  vascular cell adhesion molecule 1
AliasesCD106; INCAM-100
GeneCards (Weizmann)VCAM1
Ensembl hg19 (Hinxton)ENSG00000162692 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162692 [Gene_View]  chr1:100719640-100739046 [Contig_View]  VCAM1 [Vega]
ICGC DataPortalENSG00000162692
TCGA cBioPortalVCAM1
AceView (NCBI)VCAM1
Genatlas (Paris)VCAM1
WikiGenes7412
SOURCE (Princeton)VCAM1
Genetics Home Reference (NIH)VCAM1
Genomic and cartography
GoldenPath hg38 (UCSC)VCAM1  -     chr1:100719640-100739046 +  1p21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)VCAM1  -     1p21.2   [Description]    (hg19-Feb_2009)
EnsemblVCAM1 - 1p21.2 [CytoView hg19]  VCAM1 - 1p21.2 [CytoView hg38]
Mapping of homologs : NCBIVCAM1 [Mapview hg19]  VCAM1 [Mapview hg38]
OMIM192225   
Gene and transcription
Genbank (Entrez)AK223266 AK291732 AK296692 AU121762 BC017276
RefSeq transcript (Entrez)NM_001078 NM_001199834 NM_080682
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)VCAM1
Cluster EST : UnigeneHs.109225 [ NCBI ]
CGAP (NCI)Hs.109225
Alternative Splicing GalleryENSG00000162692
Gene ExpressionVCAM1 [ NCBI-GEO ]   VCAM1 [ EBI - ARRAY_EXPRESS ]   VCAM1 [ SEEK ]   VCAM1 [ MEM ]
Gene Expression Viewer (FireBrowse)VCAM1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7412
GTEX Portal (Tissue expression)VCAM1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP19320   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP19320  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP19320
Splice isoforms : SwissVarP19320
PhosPhoSitePlusP19320
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)ICAM_VCAM_N    Ig-like_dom    Ig-like_fold    Ig_C2-set    Ig_I-set    Ig_sub    Ig_sub2    Ig_V-set    Immunoglobulin    VCAM-1   
Domain families : Pfam (Sanger)C2-set (PF05790)    I-set (PF07679)    ig (PF00047)   
Domain families : Pfam (NCBI)pfam05790    pfam07679    pfam00047   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  IGv (SM00406)  
Conserved Domain (NCBI)VCAM1
DMDM Disease mutations7412
Blocks (Seattle)VCAM1
PDB (SRS)1IJ9    1VCA    1VSC   
PDB (PDBSum)1IJ9    1VCA    1VSC   
PDB (IMB)1IJ9    1VCA    1VSC   
PDB (RSDB)1IJ9    1VCA    1VSC   
Structural Biology KnowledgeBase1IJ9    1VCA    1VSC   
SCOP (Structural Classification of Proteins)1IJ9    1VCA    1VSC   
CATH (Classification of proteins structures)1IJ9    1VCA    1VSC   
SuperfamilyP19320
Human Protein AtlasENSG00000162692
Peptide AtlasP19320
HPRD01888
IPIIPI00018136   IPI00082827   IPI00643490   IPI00643090   
Protein Interaction databases
DIP (DOE-UCLA)P19320
IntAct (EBI)P19320
FunCoupENSG00000162692
BioGRIDVCAM1
STRING (EMBL)VCAM1
ZODIACVCAM1
Ontologies - Pathways
QuickGOP19320
Ontology : AmiGOresponse to hypoxia  podosome  acute inflammatory response  chronic inflammatory response  integrin binding  integrin binding  extracellular space  early endosome  endoplasmic reticulum  Golgi apparatus  plasma membrane  microvillus  cell adhesion  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  leukocyte cell-cell adhesion  cell-matrix adhesion  aging  response to nutrient  primary amine oxidase activity  amine metabolic process  external side of plasma membrane  cell surface  response to zinc ion  response to ionizing radiation  integral component of membrane  viral process  membrane to membrane docking  filopodium  B cell differentiation  extracellular matrix organization  response to lipopolysaccharide  response to nicotine  calcium-mediated signaling using intracellular calcium source  cellular response to vascular endothelial growth factor stimulus  positive regulation of T cell proliferation  sarcolemma  apical part of cell  response to ethanol  regulation of immune response  cell adhesion molecule binding  cell adhesion molecule binding  leukocyte tethering or rolling  leukocyte tethering or rolling  oxidation-reduction process  cell chemotaxis  interferon-gamma-mediated signaling pathway  extracellular exosome  alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex  cellular response to tumor necrosis factor  
Ontology : EGO-EBIresponse to hypoxia  podosome  acute inflammatory response  chronic inflammatory response  integrin binding  integrin binding  extracellular space  early endosome  endoplasmic reticulum  Golgi apparatus  plasma membrane  microvillus  cell adhesion  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  leukocyte cell-cell adhesion  cell-matrix adhesion  aging  response to nutrient  primary amine oxidase activity  amine metabolic process  external side of plasma membrane  cell surface  response to zinc ion  response to ionizing radiation  integral component of membrane  viral process  membrane to membrane docking  filopodium  B cell differentiation  extracellular matrix organization  response to lipopolysaccharide  response to nicotine  calcium-mediated signaling using intracellular calcium source  cellular response to vascular endothelial growth factor stimulus  positive regulation of T cell proliferation  sarcolemma  apical part of cell  response to ethanol  regulation of immune response  cell adhesion molecule binding  cell adhesion molecule binding  leukocyte tethering or rolling  leukocyte tethering or rolling  oxidation-reduction process  cell chemotaxis  interferon-gamma-mediated signaling pathway  extracellular exosome  alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex  cellular response to tumor necrosis factor  
Pathways : BIOCARTACells and Molecules involved in local acute inflammatory response [Genes]    Adhesion and Diapedesis of Lymphocytes [Genes]   
Pathways : KEGGNF-kappa B signaling pathway    Cell adhesion molecules (CAMs)    TNF signaling pathway    Leukocyte transendothelial migration    African trypanosomiasis    Malaria    HTLV-I infection   
NDEx NetworkVCAM1
Atlas of Cancer Signalling NetworkVCAM1
Wikipedia pathwaysVCAM1
Orthology - Evolution
OrthoDB7412
GeneTree (enSembl)ENSG00000162692
Phylogenetic Trees/Animal Genes : TreeFamVCAM1
HOVERGENP19320
HOGENOMP19320
Homologs : HomoloGeneVCAM1
Homology/Alignments : Family Browser (UCSC)VCAM1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVCAM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VCAM1
dbVarVCAM1
ClinVarVCAM1
1000_GenomesVCAM1 
Exome Variant ServerVCAM1
ExAC (Exome Aggregation Consortium)VCAM1 (select the gene name)
Genetic variants : HAPMAP7412
Genomic Variants (DGV)VCAM1 [DGVbeta]
DECIPHERVCAM1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisVCAM1 
Mutations
ICGC Data PortalVCAM1 
TCGA Data PortalVCAM1 
Broad Tumor PortalVCAM1
OASIS PortalVCAM1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVCAM1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDVCAM1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch VCAM1
DgiDB (Drug Gene Interaction Database)VCAM1
DoCM (Curated mutations)VCAM1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VCAM1 (select a term)
intoGenVCAM1
Cancer3DVCAM1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM192225   
Orphanet
MedgenVCAM1
Genetic Testing Registry VCAM1
NextProtP19320 [Medical]
TSGene7412
GENETestsVCAM1
Target ValidationVCAM1
Huge Navigator VCAM1 [HugePedia]
snp3D : Map Gene to Disease7412
BioCentury BCIQVCAM1
ClinGenVCAM1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7412
Chemical/Pharm GKB GenePA37286
Clinical trialVCAM1
Miscellaneous
canSAR (ICR)VCAM1 (select the gene name)
Probes
Litterature
PubMed495 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVCAM1
EVEXVCAM1
GoPubMedVCAM1
iHOPVCAM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 14:11:28 CEST 2017

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