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VCPKMT (valosin containing protein lysine (K) methyltransferase)

Identity

Alias_namesC14orf138
METTL21D
chromosome 14 open reading frame 138
methyltransferase like 21D
valosin containing protein lysine (K) methyltransferase
Alias_symbol (synonym)VCP-KMT
Other alias
HGNC (Hugo) VCPKMT
LocusID (NCBI) 79609
Atlas_Id 75590
Location 14q21.3  [Link to chromosome band 14q21]
Location_base_pair Starts at 50575350 and ends at 50583297 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
NEMF (14q21.3) / VCPKMT (14q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)VCPKMT   20352
Cards
Entrez_Gene (NCBI)VCPKMT  79609  valosin containing protein lysine (K) methyltransferase
AliasesC14orf138; METTL21D; VCP-KMT
GeneCards (Weizmann)VCPKMT
Ensembl hg19 (Hinxton)ENSG00000100483 [Gene_View]  chr14:50575350-50583297 [Contig_View]  VCPKMT [Vega]
Ensembl hg38 (Hinxton)ENSG00000100483 [Gene_View]  chr14:50575350-50583297 [Contig_View]  VCPKMT [Vega]
ICGC DataPortalENSG00000100483
TCGA cBioPortalVCPKMT
AceView (NCBI)VCPKMT
Genatlas (Paris)VCPKMT
WikiGenes79609
SOURCE (Princeton)VCPKMT
Genetics Home Reference (NIH)VCPKMT
Genomic and cartography
GoldenPath hg19 (UCSC)VCPKMT  -     chr14:50575350-50583297 -  14q21.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)VCPKMT  -     14q21.3   [Description]    (hg38-Dec_2013)
EnsemblVCPKMT - 14q21.3 [CytoView hg19]  VCPKMT - 14q21.3 [CytoView hg38]
Mapping of homologs : NCBIVCPKMT [Mapview hg19]  VCPKMT [Mapview hg38]
OMIM615260   
Gene and transcription
Genbank (Entrez)AK023982 AK129564 BC027585 BC105118 BC143673
RefSeq transcript (Entrez)NM_001040662 NM_024558
RefSeq genomic (Entrez)NC_000014 NC_018925 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)VCPKMT
Cluster EST : UnigeneHs.558541 [ NCBI ]
CGAP (NCI)Hs.558541
Alternative Splicing GalleryENSG00000100483
Gene ExpressionVCPKMT [ NCBI-GEO ]   VCPKMT [ EBI - ARRAY_EXPRESS ]   VCPKMT [ SEEK ]   VCPKMT [ MEM ]
Gene Expression Viewer (FireBrowse)VCPKMT [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79609
GTEX Portal (Tissue expression)VCPKMT
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H867   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H867  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H867
Splice isoforms : SwissVarQ9H867
Catalytic activity : Enzyme2.1.1.- [ Enzyme-Expasy ]   2.1.1.-2.1.1.- [ IntEnz-EBI ]   2.1.1.- [ BRENDA ]   2.1.1.- [ KEGG ]   
PhosPhoSitePlusQ9H867
Domains : Interpro (EBI)Nicotinamide_N-MeTfrase-like    SAM-dependent_MTases   
Domain families : Pfam (Sanger)Methyltransf_16 (PF10294)   
Domain families : Pfam (NCBI)pfam10294   
Conserved Domain (NCBI)VCPKMT
DMDM Disease mutations79609
Blocks (Seattle)VCPKMT
PDB (SRS)4LG1   
PDB (PDBSum)4LG1   
PDB (IMB)4LG1   
PDB (RSDB)4LG1   
Structural Biology KnowledgeBase4LG1   
SCOP (Structural Classification of Proteins)4LG1   
CATH (Classification of proteins structures)4LG1   
SuperfamilyQ9H867
Human Protein AtlasENSG00000100483
Peptide AtlasQ9H867
HPRD16605
IPIIPI00759651   IPI00386414   IPI00941260   IPI00852898   IPI00873433   
Protein Interaction databases
DIP (DOE-UCLA)Q9H867
IntAct (EBI)Q9H867
FunCoupENSG00000100483
BioGRIDVCPKMT
STRING (EMBL)VCPKMT
ZODIACVCPKMT
Ontologies - Pathways
QuickGOQ9H867
Ontology : AmiGOprotein binding  cellular_component  cytoplasm  protein-lysine N-methyltransferase activity  peptidyl-lysine trimethylation  
Ontology : EGO-EBIprotein binding  cellular_component  cytoplasm  protein-lysine N-methyltransferase activity  peptidyl-lysine trimethylation  
NDEx NetworkVCPKMT
Atlas of Cancer Signalling NetworkVCPKMT
Wikipedia pathwaysVCPKMT
Orthology - Evolution
OrthoDB79609
GeneTree (enSembl)ENSG00000100483
Phylogenetic Trees/Animal Genes : TreeFamVCPKMT
HOVERGENQ9H867
HOGENOMQ9H867
Homologs : HomoloGeneVCPKMT
Homology/Alignments : Family Browser (UCSC)VCPKMT
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVCPKMT [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VCPKMT
dbVarVCPKMT
ClinVarVCPKMT
1000_GenomesVCPKMT 
Exome Variant ServerVCPKMT
ExAC (Exome Aggregation Consortium)VCPKMT (select the gene name)
Genetic variants : HAPMAP79609
Genomic Variants (DGV)VCPKMT [DGVbeta]
DECIPHER (Syndromes)14:50575350-50583297  ENSG00000100483
CONAN: Copy Number AnalysisVCPKMT 
Mutations
ICGC Data PortalVCPKMT 
TCGA Data PortalVCPKMT 
Broad Tumor PortalVCPKMT
OASIS PortalVCPKMT [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDVCPKMT
BioMutasearch VCPKMT
DgiDB (Drug Gene Interaction Database)VCPKMT
DoCM (Curated mutations)VCPKMT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VCPKMT (select a term)
intoGenVCPKMT
Cancer3DVCPKMT(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615260   
Orphanet
MedgenVCPKMT
Genetic Testing Registry VCPKMT
NextProtQ9H867 [Medical]
TSGene79609
GENETestsVCPKMT
Huge Navigator VCPKMT [HugePedia]
snp3D : Map Gene to Disease79609
BioCentury BCIQVCPKMT
ClinGenVCPKMT
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79609
Chemical/Pharm GKB GenePA134866014
Clinical trialVCPKMT
Miscellaneous
canSAR (ICR)VCPKMT (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVCPKMT
EVEXVCPKMT
GoPubMedVCPKMT
iHOPVCPKMT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:51:10 CET 2017

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