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VDAC2 (voltage dependent anion channel 2)

Identity

Alias (NCBI)POR
HGNC (Hugo) VDAC2
LocusID (NCBI) 7417
Atlas_Id 55282
Location 10q22.2  [Link to chromosome band 10q22]
Location_base_pair Starts at 75210154 and ends at 75231448 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)VDAC2   12672
Cards
Entrez_Gene (NCBI)VDAC2    voltage dependent anion channel 2
AliasesPOR
GeneCards (Weizmann)VDAC2
Ensembl hg19 (Hinxton)ENSG00000165637 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165637 [Gene_View]  ENSG00000165637 [Sequence]  chr10:75210154-75231448 [Contig_View]  VDAC2 [Vega]
ICGC DataPortalENSG00000165637
TCGA cBioPortalVDAC2
AceView (NCBI)VDAC2
Genatlas (Paris)VDAC2
SOURCE (Princeton)VDAC2
Genetics Home Reference (NIH)VDAC2
Genomic and cartography
GoldenPath hg38 (UCSC)VDAC2  -     chr10:75210154-75231448 +  10q22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)VDAC2  -     10q22.2   [Description]    (hg19-Feb_2009)
GoldenPathVDAC2 - 10q22.2 [CytoView hg19]  VDAC2 - 10q22.2 [CytoView hg38]
ImmunoBaseENSG00000165637
Genome Data Viewer NCBIVDAC2 [Mapview hg19]  
OMIM193245   
Gene and transcription
Genbank (Entrez)AK296635 AK315919 BC000165 BC012883 BC072407
RefSeq transcript (Entrez)NM_001184783 NM_001184823 NM_001324087 NM_001324088 NM_001324089 NM_001324090 NM_001391963 NM_003375
Consensus coding sequences : CCDS (NCBI)VDAC2
Gene ExpressionVDAC2 [ NCBI-GEO ]   VDAC2 [ EBI - ARRAY_EXPRESS ]   VDAC2 [ SEEK ]   VDAC2 [ MEM ]
Gene Expression Viewer (FireBrowse)VDAC2 [ Firebrowse - Broad ]
GenevisibleExpression of VDAC2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7417
GTEX Portal (Tissue expression)VDAC2
Human Protein AtlasENSG00000165637-VDAC2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP45880   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP45880  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP45880
PhosPhoSitePlusP45880
Domaine pattern : Prosite (Expaxy)EUKARYOTIC_PORIN (PS00558)   
Domains : Interpro (EBI)Porin_dom_sf    Porin_Euk    Porin_Euk/Tom40    VDAC2   
Domain families : Pfam (Sanger)Porin_3 (PF01459)   
Domain families : Pfam (NCBI)pfam01459   
Conserved Domain (NCBI)VDAC2
SuperfamilyP45880
AlphaFold pdb e-kbP45880   
Human Protein Atlas [tissue]ENSG00000165637-VDAC2 [tissue]
HPRD01904
Protein Interaction databases
DIP (DOE-UCLA)P45880
IntAct (EBI)P45880
BioGRIDVDAC2
STRING (EMBL)VDAC2
ZODIACVDAC2
Ontologies - Pathways
QuickGOP45880
Ontology : AmiGOnucleotide binding  acrosomal vesicle  protein binding  nucleus  mitochondrion  mitochondrion  mitochondrial outer membrane  anion transport  binding of sperm to zona pellucida  synaptic vesicle  voltage-gated anion channel activity  voltage-gated anion channel activity  porin activity  cholesterol binding  inorganic anion transport  membrane  phosphatidylcholine binding  mitochondrial membrane  negative regulation of protein polymerization  mitochondrial nucleoid  pore complex  ceramide binding  mitochondrial outer membrane permeabilization  anion transmembrane transport  negative regulation of intrinsic apoptotic signaling pathway  
Ontology : EGO-EBInucleotide binding  acrosomal vesicle  protein binding  nucleus  mitochondrion  mitochondrion  mitochondrial outer membrane  anion transport  binding of sperm to zona pellucida  synaptic vesicle  voltage-gated anion channel activity  voltage-gated anion channel activity  porin activity  cholesterol binding  inorganic anion transport  membrane  phosphatidylcholine binding  mitochondrial membrane  negative regulation of protein polymerization  mitochondrial nucleoid  pore complex  ceramide binding  mitochondrial outer membrane permeabilization  anion transmembrane transport  negative regulation of intrinsic apoptotic signaling pathway  
Pathways : KEGGCalcium signaling pathway    Parkinson's disease    Huntington's disease    HTLV-I infection   
NDEx NetworkVDAC2
Atlas of Cancer Signalling NetworkVDAC2
Wikipedia pathwaysVDAC2
Orthology - Evolution
OrthoDB7417
GeneTree (enSembl)ENSG00000165637
Phylogenetic Trees/Animal Genes : TreeFamVDAC2
Homologs : HomoloGeneVDAC2
Homology/Alignments : Family Browser (UCSC)VDAC2
Gene fusions - Rearrangements
Fusion : QuiverVDAC2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVDAC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VDAC2
dbVarVDAC2
ClinVarVDAC2
MonarchVDAC2
1000_GenomesVDAC2 
Exome Variant ServerVDAC2
GNOMAD BrowserENSG00000165637
Varsome BrowserVDAC2
ACMGVDAC2 variants
VarityP45880
Genomic Variants (DGV)VDAC2 [DGVbeta]
DECIPHERVDAC2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisVDAC2 
Mutations
ICGC Data PortalVDAC2 
TCGA Data PortalVDAC2 
Broad Tumor PortalVDAC2
OASIS PortalVDAC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVDAC2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DVDAC2
Mutations and Diseases : HGMDVDAC2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaVDAC2
DgiDB (Drug Gene Interaction Database)VDAC2
DoCM (Curated mutations)VDAC2
CIViC (Clinical Interpretations of Variants in Cancer)VDAC2
Cancer3DVDAC2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM193245   
Orphanet
DisGeNETVDAC2
MedgenVDAC2
Genetic Testing Registry VDAC2
NextProtP45880 [Medical]
GENETestsVDAC2
Target ValidationVDAC2
Huge Navigator VDAC2 [HugePedia]
ClinGenVDAC2
Clinical trials, drugs, therapy
MyCancerGenomeVDAC2
Protein Interactions : CTDVDAC2
Pharm GKB GenePA37295
PharosP45880
Clinical trialVDAC2
Miscellaneous
canSAR (ICR)VDAC2
HarmonizomeVDAC2
DataMed IndexVDAC2
Probes
Litterature
PubMed164 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXVDAC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:37:57 CEST 2021

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