Identity
HGNC
LOCATION
4q34.3
LOCUSID
ALIAS
Flt4-L,LMPH1D,LMPHM4,VRP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7424
MIM: 601528
HGNC: 12682
Ensembl: ENSG00000150630
Variants:
dbSNP: 7424
ClinVar: 7424
TCGA: ENSG00000150630
COSMIC: VEGFC
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000150630 | ENST00000618562 | P49767 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA130232992 | bevacizumab | Chemical | Pathway | associated | 20124951 | ||
| PA166118342 | aflibercept | Chemical | Pathway | associated | 20124951 | ||
| PA28180 | FLT1 | Gene | Pathway | associated | 20124951 | ||
| PA30086 | KDR | Gene | Pathway | associated | 20124951 | ||
| PA31783 | NRP1 | Gene | Pathway | associated | 20124951 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37942701 | 2024 | Association of plasma NRP2 and VEGF-C levels with prostate cancer disease severity. | 0 |
| 38092144 | 2024 | Neovascularization directed by CAVIN1/CCBE1/VEGFC confers TMZ-resistance in glioblastoma. | 0 |
| 38092160 | 2024 | Correlation of serum VEGF-C, ANGPTL4, and activin A levels with frailty. | 0 |
| 38211648 | 2024 | DHCR7 promotes lymph node metastasis in cervical cancer through cholesterol reprogramming-mediated activation of the KANK4/PI3K/AKT axis and VEGF-C secretion. | 0 |
| 38372116 | 2024 | Comparative study on the expression of Pax3, Rad51 and VEGF-C in esophageal gastric junction adenocarcinoma and distal gastric adenocarcinoma. | 0 |
| 38728943 | 2024 | miR-455-3p regulates lymphangiogenesis in silicosis by regulating VEGF-C/VEGFR3. | 0 |
| 37942701 | 2024 | Association of plasma NRP2 and VEGF-C levels with prostate cancer disease severity. | 0 |
| 38092144 | 2024 | Neovascularization directed by CAVIN1/CCBE1/VEGFC confers TMZ-resistance in glioblastoma. | 0 |
| 38092160 | 2024 | Correlation of serum VEGF-C, ANGPTL4, and activin A levels with frailty. | 0 |
| 38211648 | 2024 | DHCR7 promotes lymph node metastasis in cervical cancer through cholesterol reprogramming-mediated activation of the KANK4/PI3K/AKT axis and VEGF-C secretion. | 0 |
| 38372116 | 2024 | Comparative study on the expression of Pax3, Rad51 and VEGF-C in esophageal gastric junction adenocarcinoma and distal gastric adenocarcinoma. | 0 |
| 38728943 | 2024 | miR-455-3p regulates lymphangiogenesis in silicosis by regulating VEGF-C/VEGFR3. | 0 |
| 36617735 | 2023 | CircHGS enhances the progression of bladder cancer by regulating the miR-513a-5p/VEGFC axis and activating the AKT/mTOR signaling pathway. | 1 |
| 36682577 | 2023 | Diagnostic and prognostic value of plasma cell-free DNA combined with VEGF-C in laryngeal squamous cell carcinoma. | 4 |
| 36766725 | 2023 | Macrophages Promote Ovarian Cancer-Mesothelial Cell Adhesion by Upregulation of ITGA2 and VEGFC in Mesothelial Cells. | 0 |
Citation
Dessen P
VEGFC (vascular endothelial growth factor C)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42789/vegfc
