VENTX (VENT homeobox)

2003-12-01  

Identity

HGNC
LOCATION
10q26.3
LOCUSID
ALIAS
HPX42B,NA88A,VENTX2

Other Information

Locus ID:

NCBI: 27287
MIM: 607158
HGNC: 13639
Ensembl: ENSG00000151650

Variants:

dbSNP: 27287
ClinVar: 27287
TCGA: ENSG00000151650
COSMIC: VENTX

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000151650ENST00000325980O95231

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
200288612010VentX, a novel lymphoid-enhancing factor/T-cell factor-associated transcription repressor, is a putative tumor suppressor.14
208338192010The vent-like homeobox gene VENTX promotes human myeloid differentiation and is highly expressed in acute myeloid leukemia.12
216704962011The homeobox transcription factor VentX controls human macrophage terminal differentiation and proinflammatory activation.10
213252732011VentX trans-activates p53 and p16ink4a to regulate cellular senescence.9
227917092012Suppression of homeobox transcription factor VentX promotes expansion of human hematopoietic stem/multipotent progenitor cells.6
247067562014Homeobox transcription factor VentX regulates differentiation and maturation of human dendritic cells.4
298720442018The homeobox protein VentX reverts immune suppression in the tumor microenvironment.3
271755922016Homeobox protein VentX induces p53-independent apoptosis in cancer cells.2
278886322016VENTX induces expansion of primitive erythroid cells and contributes to the development of acute myeloid leukemia in mice.1

Citation

Dessen P

VENTX (VENT homeobox)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/42790/ventx