Atlas of Genetics and Cytogenetics in Oncology and Haematology

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VEZF1 (vascular endothelial zinc finger 1)

Identity

Alias (NCBI)DB1
ZNF161
HGNC (Hugo) VEZF1
HGNC Alias symbDB1
HGNC Previous nameZNF161
HGNC Previous namezinc finger protein 161
LocusID (NCBI) 7716
Atlas_Id 75601
Location 17q22  [Link to chromosome band 17q22]
Location_base_pair Starts at 57971549 and ends at 57988254 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MRPS23 (17q22) / VEZF1 (17q22)VEZF1 (17q22) / DDX42 (17q23.3)VEZF1 (17q22) / VEZF1 (17q22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(17;17)(q22;q23) VEZF1/DDX42

External links

Nomenclature
HGNC (Hugo)VEZF1   12949
Cards
Entrez_Gene (NCBI)VEZF1    vascular endothelial zinc finger 1
AliasesDB1; ZNF161
GeneCards (Weizmann)VEZF1
Ensembl hg19 (Hinxton)ENSG00000136451 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000136451 [Gene_View]  ENSG00000136451 [Sequence]  chr17:57971549-57988254 [Contig_View]  VEZF1 [Vega]
ICGC DataPortalENSG00000136451
TCGA cBioPortalVEZF1
AceView (NCBI)VEZF1
Genatlas (Paris)VEZF1
SOURCE (Princeton)VEZF1
Genetics Home Reference (NIH)VEZF1
Genomic and cartography
GoldenPath hg38 (UCSC)VEZF1  -     chr17:57971549-57988254 -  17q22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)VEZF1  -     17q22   [Description]    (hg19-Feb_2009)
GoldenPathVEZF1 - 17q22 [CytoView hg19]  VEZF1 - 17q22 [CytoView hg38]
ImmunoBaseENSG00000136451
genome Data Viewer NCBIVEZF1 [Mapview hg19]  
OMIM606747   
Gene and transcription
Genbank (Entrez)AA195154 AK058024 BG718897 BU729102 BX648862
RefSeq transcript (Entrez)NM_001330393 NM_007146
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)VEZF1
Alternative Splicing GalleryENSG00000136451
Gene ExpressionVEZF1 [ NCBI-GEO ]   VEZF1 [ EBI - ARRAY_EXPRESS ]   VEZF1 [ SEEK ]   VEZF1 [ MEM ]
Gene Expression Viewer (FireBrowse)VEZF1 [ Firebrowse - Broad ]
GenevisibleExpression of VEZF1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7716
GTEX Portal (Tissue expression)VEZF1
Human Protein AtlasENSG00000136451-VEZF1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14119   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14119  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14119
Splice isoforms : SwissVarQ14119
PhosPhoSitePlusQ14119
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam00096   
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)VEZF1
Blocks (Seattle)VEZF1
SuperfamilyQ14119
Human Protein Atlas [tissue]ENSG00000136451-VEZF1 [tissue]
Peptide AtlasQ14119
HPRD08416
IPIIPI00028912   
Protein Interaction databases
DIP (DOE-UCLA)Q14119
IntAct (EBI)Q14119
BioGRIDVEZF1
STRING (EMBL)VEZF1
ZODIACVEZF1
Ontologies - Pathways
QuickGOQ14119
Ontology : AmiGORNA polymerase II regulatory region sequence-specific DNA binding  DNA-binding transcription activator activity, RNA polymerase II-specific  angiogenesis  endothelial cell development  nucleoplasm  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  cellular defense response  positive regulation of endothelial cell differentiation  positive regulation of transcription by RNA polymerase II  metal ion binding  
Ontology : EGO-EBIRNA polymerase II regulatory region sequence-specific DNA binding  DNA-binding transcription activator activity, RNA polymerase II-specific  angiogenesis  endothelial cell development  nucleoplasm  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  cellular defense response  positive regulation of endothelial cell differentiation  positive regulation of transcription by RNA polymerase II  metal ion binding  
NDEx NetworkVEZF1
Atlas of Cancer Signalling NetworkVEZF1
Wikipedia pathwaysVEZF1
Orthology - Evolution
OrthoDB7716
GeneTree (enSembl)ENSG00000136451
Phylogenetic Trees/Animal Genes : TreeFamVEZF1
HOGENOMQ14119
Homologs : HomoloGeneVEZF1
Homology/Alignments : Family Browser (UCSC)VEZF1
Gene fusions - Rearrangements
Fusion : QuiverVEZF1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVEZF1 [hg38]
dbVarVEZF1
ClinVarVEZF1
MonarchVEZF1
1000_GenomesVEZF1 
Exome Variant ServerVEZF1
GNOMAD BrowserENSG00000136451
Varsome BrowserVEZF1
Genomic Variants (DGV)VEZF1 [DGVbeta]
DECIPHERVEZF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisVEZF1 
Mutations
ICGC Data PortalVEZF1 
TCGA Data PortalVEZF1 
Broad Tumor PortalVEZF1
OASIS PortalVEZF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVEZF1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DVEZF1
Mutations and Diseases : HGMDVEZF1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch VEZF1
DgiDB (Drug Gene Interaction Database)VEZF1
DoCM (Curated mutations)VEZF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VEZF1 (select a term)
intoGenVEZF1
Cancer3DVEZF1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606747   
Orphanet
DisGeNETVEZF1
MedgenVEZF1
Genetic Testing Registry VEZF1
NextProtQ14119 [Medical]
GENETestsVEZF1
Target ValidationVEZF1
Huge Navigator VEZF1 [HugePedia]
ClinGenVEZF1
Clinical trials, drugs, therapy
MyCancerGenomeVEZF1
Protein Interactions : CTD
Pharm GKB GenePA162408823
Clinical trialVEZF1
Miscellaneous
canSAR (ICR)VEZF1 (select the gene name)
HarmonizomeVEZF1
DataMed IndexVEZF1
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVEZF1
EVEXVEZF1
GoPubMedVEZF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Dec 5 17:34:26 CET 2020
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