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VGLL3 (vestigial like family member 3)

Identity

Alias_namesvestigial like 3 (Drosophila)
vestigial-like family member 3
Alias_symbol (synonym)VGL-3
Other aliasVGL3
HGNC (Hugo) VGLL3
LocusID (NCBI) 389136
Atlas_Id 40607
Location 3p12.1  [Link to chromosome band 3p12]
Location_base_pair Starts at 86961906 and ends at 86991123 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FADS1 (11q12.2) / VGLL3 (3p12.1)PAK2 (3q29) / VGLL3 (3p12.1)SIGMAR1 (9p13.3) / VGLL3 (3p12.1)
VGLL3 (3p12.1) / PBXIP1 (1q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  Soft tissue tumors: an overview
Soft Tissues: Myxoinflammatory fibroblastic sarcoma with t(1;10)(p22;q24) FGF8/
Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)VGLL3   24327
Cards
Entrez_Gene (NCBI)VGLL3  389136  vestigial like family member 3
AliasesVGL-3; VGL3
GeneCards (Weizmann)VGLL3
Ensembl hg19 (Hinxton)ENSG00000206538 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000206538 [Gene_View]  chr3:86961906-86991123 [Contig_View]  VGLL3 [Vega]
ICGC DataPortalENSG00000206538
TCGA cBioPortalVGLL3
AceView (NCBI)VGLL3
Genatlas (Paris)VGLL3
WikiGenes389136
SOURCE (Princeton)VGLL3
Genetics Home Reference (NIH)VGLL3
Genomic and cartography
GoldenPath hg38 (UCSC)VGLL3  -     chr3:86961906-86991123 -  3p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)VGLL3  -     3p12.1   [Description]    (hg19-Feb_2009)
EnsemblVGLL3 - 3p12.1 [CytoView hg19]  VGLL3 - 3p12.1 [CytoView hg38]
Mapping of homologs : NCBIVGLL3 [Mapview hg19]  VGLL3 [Mapview hg38]
OMIM609980   
Gene and transcription
Genbank (Entrez)AA455617 AF099505 AI379920 AK095826 BC017383
RefSeq transcript (Entrez)NM_001320493 NM_001320494 NM_016206
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)VGLL3
Cluster EST : UnigeneHs.744116 [ NCBI ]
CGAP (NCI)Hs.744116
Alternative Splicing GalleryENSG00000206538
Gene ExpressionVGLL3 [ NCBI-GEO ]   VGLL3 [ EBI - ARRAY_EXPRESS ]   VGLL3 [ SEEK ]   VGLL3 [ MEM ]
Gene Expression Viewer (FireBrowse)VGLL3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)389136
GTEX Portal (Tissue expression)VGLL3
Human Protein AtlasENSG00000206538-VGLL3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA8MV65   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA8MV65  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA8MV65
Splice isoforms : SwissVarA8MV65
PhosPhoSitePlusA8MV65
Domains : Interpro (EBI)TDU_repeat    Vg_fam   
Domain families : Pfam (Sanger)Vg_Tdu (PF07545)   
Domain families : Pfam (NCBI)pfam07545   
Domain families : Smart (EMBL)TDU (SM00711)  
Conserved Domain (NCBI)VGLL3
DMDM Disease mutations389136
Blocks (Seattle)VGLL3
SuperfamilyA8MV65
Human Protein Atlas [tissue]ENSG00000206538-VGLL3 [tissue]
Peptide AtlasA8MV65
HPRD13431
IPIIPI00514518   IPI00874001   IPI00007817   IPI00945509   
Protein Interaction databases
DIP (DOE-UCLA)A8MV65
IntAct (EBI)A8MV65
FunCoupENSG00000206538
BioGRIDVGLL3
STRING (EMBL)VGLL3
ZODIACVGLL3
Ontologies - Pathways
QuickGOA8MV65
Ontology : AmiGOtranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding  nucleus  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  
Ontology : EGO-EBItranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding  nucleus  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  
NDEx NetworkVGLL3
Atlas of Cancer Signalling NetworkVGLL3
Wikipedia pathwaysVGLL3
Orthology - Evolution
OrthoDB389136
GeneTree (enSembl)ENSG00000206538
Phylogenetic Trees/Animal Genes : TreeFamVGLL3
HOVERGENA8MV65
HOGENOMA8MV65
Homologs : HomoloGeneVGLL3
Homology/Alignments : Family Browser (UCSC)VGLL3
Gene fusions - Rearrangements
Fusion : MitelmanPAK2/VGLL3 [3q29/3p12.1]  [t(3;3)(p12;q29)]  
Tumor Fusion PortalVGLL3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVGLL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VGLL3
dbVarVGLL3
ClinVarVGLL3
1000_GenomesVGLL3 
Exome Variant ServerVGLL3
ExAC (Exome Aggregation Consortium)ENSG00000206538
GNOMAD BrowserENSG00000206538
Genetic variants : HAPMAP389136
Genomic Variants (DGV)VGLL3 [DGVbeta]
DECIPHERVGLL3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisVGLL3 
Mutations
ICGC Data PortalVGLL3 
TCGA Data PortalVGLL3 
Broad Tumor PortalVGLL3
OASIS PortalVGLL3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVGLL3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDVGLL3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch VGLL3
DgiDB (Drug Gene Interaction Database)VGLL3
DoCM (Curated mutations)VGLL3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VGLL3 (select a term)
intoGenVGLL3
Cancer3DVGLL3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609980   
Orphanet
DisGeNETVGLL3
MedgenVGLL3
Genetic Testing Registry VGLL3
NextProtA8MV65 [Medical]
TSGene389136
GENETestsVGLL3
Target ValidationVGLL3
Huge Navigator VGLL3 [HugePedia]
snp3D : Map Gene to Disease389136
BioCentury BCIQVGLL3
ClinGenVGLL3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD389136
Chemical/Pharm GKB GenePA142670628
Clinical trialVGLL3
Miscellaneous
canSAR (ICR)VGLL3 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVGLL3
EVEXVGLL3
GoPubMedVGLL3
iHOPVGLL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:41:19 CET 2017

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