Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

VGLL4 (vestigial like family member 4)

Identity

Alias (NCBI)VGL-4
HGNC (Hugo) VGLL4
HGNC Alias symbKIAA0121
HGNC Previous namevestigial like 4 (Drosophila)
 vestigial-like family member 4
LocusID (NCBI) 9686
Atlas_Id 52512
Location 3p25.3  [Link to chromosome band 3p25]
Location_base_pair Starts at 11556069 and ends at 11720539 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PDE3A (12p12.2) / VGLL4 (3p25.3)VGLL4 (3p25.3) / ATG7 (3p25.3)VGLL4 (3p25.3) / CHL1 (3p26.3)
VGLL4 (3p25.3) / FOXP1 (3p13)VGLL4 (3p25.3) / HILPDA (7q32.1)VGLL4 (3p25.3) / LIMD1 (3p21.31)
VGLL4 (3p25.3) / PRKG1 (10q11.23)VGLL4 (3p25.3) / SH3BP5 (3p25.1)VGLL4 (3p25.3) / SYNPR (3p14.2)
VGLL4 (3p25.3) / TAMM41 (3p25.2)VGLL4 (3p25.3) / UBE2E3 (2q31.3)VGLL4 (3p25.3) / VGLL4 (3p25.3)
VGLL4 3p25.3 / CHL1 3p26.3VGLL4 3p25.3 / FOXP1 3p13VGLL4 3p25.3 / LIMD1 3p21.31
VGLL4 3p25.3 / SH3BP5 3p25.1VGLL4 3p25.3 / SYNPR 3p14.2VGLL4 3p25.3 / TAMM41 3p25.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)VGLL4   28966
Cards
Entrez_Gene (NCBI)VGLL4    vestigial like family member 4
AliasesVGL-4
GeneCards (Weizmann)VGLL4
Ensembl hg19 (Hinxton)ENSG00000144560 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000144560 [Gene_View]  ENSG00000144560 [Sequence]  chr3:11556069-11720539 [Contig_View]  VGLL4 [Vega]
ICGC DataPortalENSG00000144560
TCGA cBioPortalVGLL4
AceView (NCBI)VGLL4
Genatlas (Paris)VGLL4
SOURCE (Princeton)VGLL4
Genetics Home Reference (NIH)VGLL4
Genomic and cartography
GoldenPath hg38 (UCSC)VGLL4  -     chr3:11556069-11720539 -  3p25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)VGLL4  -     3p25.3   [Description]    (hg19-Feb_2009)
GoldenPathVGLL4 - 3p25.3 [CytoView hg19]  VGLL4 - 3p25.3 [CytoView hg38]
ImmunoBaseENSG00000144560
Genome Data Viewer NCBIVGLL4 [Mapview hg19]  
OMIM618692   
Gene and transcription
Genbank (Entrez)AI809612 AK126479 AK130542 AK300344 AK307708
RefSeq transcript (Entrez)NM_001128219 NM_001128220 NM_001128221 NM_001284390 NM_001284391 NM_014667
Consensus coding sequences : CCDS (NCBI)VGLL4
Gene ExpressionVGLL4 [ NCBI-GEO ]   VGLL4 [ EBI - ARRAY_EXPRESS ]   VGLL4 [ SEEK ]   VGLL4 [ MEM ]
Gene Expression Viewer (FireBrowse)VGLL4 [ Firebrowse - Broad ]
GenevisibleExpression of VGLL4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9686
GTEX Portal (Tissue expression)VGLL4
Human Protein AtlasENSG00000144560-VGLL4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14135   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14135  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14135
PhosPhoSitePlusQ14135
Domains : Interpro (EBI)TDU_repeat    VGLL4   
Domain families : Pfam (Sanger)VGLL4 (PF15245)   
Domain families : Pfam (NCBI)pfam15245   
Domain families : Smart (EMBL)TDU (SM00711)  
Conserved Domain (NCBI)VGLL4
SuperfamilyQ14135
AlphaFold pdb e-kbQ14135   
Human Protein Atlas [tissue]ENSG00000144560-VGLL4 [tissue]
HPRD11672
Protein Interaction databases
DIP (DOE-UCLA)Q14135
IntAct (EBI)Q14135
BioGRIDVGLL4
STRING (EMBL)VGLL4
ZODIACVGLL4
Ontologies - Pathways
QuickGOQ14135
Ontology : AmiGOtranscription coactivator binding  protein binding  nucleus  negative regulation of Wnt signaling pathway  negative regulation of cell growth  negative regulation of hippo signaling  negative regulation of hippo signaling  negative regulation of transcription, DNA-templated  negative regulation of transcription, DNA-templated  negative regulation of cardiac muscle cell proliferation  positive regulation of cellular protein catabolic process  
Ontology : EGO-EBItranscription coactivator binding  protein binding  nucleus  negative regulation of Wnt signaling pathway  negative regulation of cell growth  negative regulation of hippo signaling  negative regulation of hippo signaling  negative regulation of transcription, DNA-templated  negative regulation of transcription, DNA-templated  negative regulation of cardiac muscle cell proliferation  positive regulation of cellular protein catabolic process  
NDEx NetworkVGLL4
Atlas of Cancer Signalling NetworkVGLL4
Wikipedia pathwaysVGLL4
Orthology - Evolution
OrthoDB9686
GeneTree (enSembl)ENSG00000144560
Phylogenetic Trees/Animal Genes : TreeFamVGLL4
Homologs : HomoloGeneVGLL4
Homology/Alignments : Family Browser (UCSC)VGLL4
Gene fusions - Rearrangements
Fusion : MitelmanVGLL4/CHL1 [3p25.3/3p26.3]  
Fusion : MitelmanVGLL4/FOXP1 [3p25.3/3p13]  
Fusion : MitelmanVGLL4/LIMD1 [3p25.3/3p21.31]  
Fusion : MitelmanVGLL4/SH3BP5 [3p25.3/3p25.1]  
Fusion : MitelmanVGLL4/SYNPR [3p25.3/3p14.2]  
Fusion : MitelmanVGLL4/TAMM41 [3p25.3/3p25.2]  
Fusion : QuiverVGLL4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVGLL4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VGLL4
dbVarVGLL4
ClinVarVGLL4
MonarchVGLL4
1000_GenomesVGLL4 
Exome Variant ServerVGLL4
GNOMAD BrowserENSG00000144560
Varsome BrowserVGLL4
ACMGVGLL4 variants
VarityQ14135
Genomic Variants (DGV)VGLL4 [DGVbeta]
DECIPHERVGLL4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisVGLL4 
Mutations
ICGC Data PortalVGLL4 
TCGA Data PortalVGLL4 
Broad Tumor PortalVGLL4
OASIS PortalVGLL4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVGLL4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DVGLL4
Mutations and Diseases : HGMDVGLL4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaVGLL4
DgiDB (Drug Gene Interaction Database)VGLL4
DoCM (Curated mutations)VGLL4
CIViC (Clinical Interpretations of Variants in Cancer)VGLL4
Cancer3DVGLL4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM618692   
Orphanet
DisGeNETVGLL4
MedgenVGLL4
Genetic Testing Registry VGLL4
NextProtQ14135 [Medical]
GENETestsVGLL4
Target ValidationVGLL4
Huge Navigator VGLL4 [HugePedia]
ClinGenVGLL4
Clinical trials, drugs, therapy
MyCancerGenomeVGLL4
Protein Interactions : CTDVGLL4
Pharm GKB GenePA128394553
PharosQ14135
Clinical trialVGLL4
Miscellaneous
canSAR (ICR)VGLL4
HarmonizomeVGLL4
DataMed IndexVGLL4
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXVGLL4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:38:00 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.