VIL1 (villin 1)

2010-02-01  

Identity

HGNC
VIL1
LOCATION
2q35
LOCUSID
7429
ALIAS
D2S1471,VIL
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7429
MIM: 193040
HGNC: 12690
Ensembl: ENSG00000127831

Variants:

dbSNP: 7429
ClinVar: 7429
TCGA: ENSG00000127831
COSMIC: VIL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000127831ENST00000248444P09327
ENSG00000127831ENST00000392114B4DV78
ENSG00000127831ENST00000419986H7C0B6
ENSG00000127831ENST00000440053P09327
ENSG00000127831ENST00000454069C9J2B5

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
183079962008Regulation of cell structure and function by actin-binding proteins: villin's perspective.51
115004852001Tyrosine phosphorylation of villin regulates the organization of the actin cytoskeleton.25
180547842008Autotaxin and lysophosphatidic acid stimulate intestinal cell motility by redistribution of the actin modifying protein villin to the developing lamellipodia.21
153427832004Regulation of cell motility by tyrosine phosphorylated villin.20
193716342009Cdx2 and the Brm-type SWI/SNF complex cooperatively regulate villin expression in gastrointestinal cells.20
256001872015Apical invasion of intestinal epithelial cells by Salmonella typhimurium requires villin to remodel the brush border actin cytoskeleton.18
171828582007Villin severing activity enhances actin-based motility in vivo.17
265377992016N-glycosylation Profiling of Colorectal Cancer Cell Lines Reveals Association of Fucosylation with Differentiation and Caudal Type Homebox 1 (CDX1)/Villin mRNA Expression.17
152720272004Functional dissection and molecular characterization of calcium-sensitive actin-capping and actin-depolymerizing sites in villin.12
242668972014BAI3, CDX2 and VIL1: a panel of three antibodies to distinguish small cell from large cell neuroendocrine lung carcinomas.12

Citation

Dessen P

VIL1 (villin 1)

Atlas Genet Cytogenet Oncol Haematol. 2010-02-01

Online version: http://atlasgeneticsoncology.org/gene/51351/vil1