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VIPR2 (vasoactive intestinal peptide receptor 2)

Identity

Alias_symbol (synonym)VPAC2
VPAC2R
Other aliasC16DUPq36.3
DUP7q36.3
PACAP-R-3
PACAP-R3
VIP-R-2
VPCAP2R
HGNC (Hugo) VIPR2
LocusID (NCBI) 7434
Atlas_Id 52563
Location 7q36.3  [Link to chromosome band 7q36]
Location_base_pair Starts at 159028175 and ends at 159144957 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
WDR60 (7q36.3) / VIPR2 (7q36.3)WDR60 7q36.3 / VIPR2 7q36.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  WDR60/VIPR2 (7q36)


External links

Nomenclature
HGNC (Hugo)VIPR2   12695
Cards
Entrez_Gene (NCBI)VIPR2  7434  vasoactive intestinal peptide receptor 2
AliasesC16DUPq36.3; DUP7q36.3; PACAP-R-3; PACAP-R3; 
VIP-R-2; VPAC2; VPAC2R; VPCAP2R
GeneCards (Weizmann)VIPR2
Ensembl hg19 (Hinxton)ENSG00000106018 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106018 [Gene_View]  ENSG00000106018 [Sequence]  chr7:159028175-159144957 [Contig_View]  VIPR2 [Vega]
ICGC DataPortalENSG00000106018
TCGA cBioPortalVIPR2
AceView (NCBI)VIPR2
Genatlas (Paris)VIPR2
WikiGenes7434
SOURCE (Princeton)VIPR2
Genetics Home Reference (NIH)VIPR2
Genomic and cartography
GoldenPath hg38 (UCSC)VIPR2  -     chr7:159028175-159144957 -  7q36.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)VIPR2  -     7q36.3   [Description]    (hg19-Feb_2009)
EnsemblVIPR2 - 7q36.3 [CytoView hg19]  VIPR2 - 7q36.3 [CytoView hg38]
Mapping of homologs : NCBIVIPR2 [Mapview hg19]  VIPR2 [Mapview hg38]
OMIM601970   
Gene and transcription
Genbank (Entrez)AK131406 AK308955 AK310386 BC010569 BT007118
RefSeq transcript (Entrez)NM_001304522 NM_001308259 NM_003382
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)VIPR2
Cluster EST : UnigeneHs.585052 [ NCBI ]
CGAP (NCI)Hs.585052
Alternative Splicing GalleryENSG00000106018
Gene ExpressionVIPR2 [ NCBI-GEO ]   VIPR2 [ EBI - ARRAY_EXPRESS ]   VIPR2 [ SEEK ]   VIPR2 [ MEM ]
Gene Expression Viewer (FireBrowse)VIPR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7434
GTEX Portal (Tissue expression)VIPR2
Human Protein AtlasENSG00000106018-VIPR2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP41587   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP41587  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP41587
Splice isoforms : SwissVarP41587
PhosPhoSitePlusP41587
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F2_1 (PS00649)    G_PROTEIN_RECEP_F2_2 (PS00650)    G_PROTEIN_RECEP_F2_3 (PS50227)    G_PROTEIN_RECEP_F2_4 (PS50261)   
Domains : Interpro (EBI)GPCR_2-like    GPCR_2_extracell_dom_sf    GPCR_2_extracellular_dom    GPCR_2_secretin-like    GPCR_2_secretin-like_CS    GPCR_2_VIP_rcpt    GPCR_2_VIP_rcpt_2   
Domain families : Pfam (Sanger)7tm_2 (PF00002)    HRM (PF02793)   
Domain families : Pfam (NCBI)pfam00002    pfam02793   
Domain families : Smart (EMBL)HormR (SM00008)  
Conserved Domain (NCBI)VIPR2
DMDM Disease mutations7434
Blocks (Seattle)VIPR2
PDB (SRS)2X57   
PDB (PDBSum)2X57   
PDB (IMB)2X57   
PDB (RSDB)2X57   
Structural Biology KnowledgeBase2X57   
SCOP (Structural Classification of Proteins)2X57   
CATH (Classification of proteins structures)2X57   
SuperfamilyP41587
Human Protein Atlas [tissue]ENSG00000106018-VIPR2 [tissue]
Peptide AtlasP41587
HPRD03576
IPIIPI00420122   IPI00739927   IPI00893908   IPI00015122   IPI00893593   IPI00893760   
Protein Interaction databases
DIP (DOE-UCLA)P41587
IntAct (EBI)P41587
FunCoupENSG00000106018
BioGRIDVIPR2
STRING (EMBL)VIPR2
ZODIACVIPR2
Ontologies - Pathways
QuickGOP41587
Ontology : AmiGOG-protein coupled receptor activity  vasoactive intestinal polypeptide receptor activity  vasoactive intestinal polypeptide receptor activity  plasma membrane  integral component of plasma membrane  signal transduction  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  activation of adenylate cyclase activity  cell-cell signaling  G-protein coupled peptide receptor activity  peptide hormone binding  negative regulation of smooth muscle cell proliferation  
Ontology : EGO-EBIG-protein coupled receptor activity  vasoactive intestinal polypeptide receptor activity  vasoactive intestinal polypeptide receptor activity  plasma membrane  integral component of plasma membrane  signal transduction  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  activation of adenylate cyclase activity  cell-cell signaling  G-protein coupled peptide receptor activity  peptide hormone binding  negative regulation of smooth muscle cell proliferation  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkVIPR2
Atlas of Cancer Signalling NetworkVIPR2
Wikipedia pathwaysVIPR2
Orthology - Evolution
OrthoDB7434
GeneTree (enSembl)ENSG00000106018
Phylogenetic Trees/Animal Genes : TreeFamVIPR2
HOVERGENP41587
HOGENOMP41587
Homologs : HomoloGeneVIPR2
Homology/Alignments : Family Browser (UCSC)VIPR2
Gene fusions - Rearrangements
Fusion : MitelmanWDR60/VIPR2 [7q36.3/7q36.3]  [t(7;7)(q36;q36)]  
Fusion PortalWDR60 7q36.3 VIPR2 7q36.3 KIRC
Fusion : QuiverVIPR2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVIPR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VIPR2
dbVarVIPR2
ClinVarVIPR2
1000_GenomesVIPR2 
Exome Variant ServerVIPR2
ExAC (Exome Aggregation Consortium)ENSG00000106018
GNOMAD BrowserENSG00000106018
Varsome BrowserVIPR2
Genetic variants : HAPMAP7434
Genomic Variants (DGV)VIPR2 [DGVbeta]
DECIPHERVIPR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisVIPR2 
Mutations
ICGC Data PortalVIPR2 
TCGA Data PortalVIPR2 
Broad Tumor PortalVIPR2
OASIS PortalVIPR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVIPR2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDVIPR2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch VIPR2
DgiDB (Drug Gene Interaction Database)VIPR2
DoCM (Curated mutations)VIPR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VIPR2 (select a term)
intoGenVIPR2
Cancer3DVIPR2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601970   
Orphanet
DisGeNETVIPR2
MedgenVIPR2
Genetic Testing Registry VIPR2
NextProtP41587 [Medical]
TSGene7434
GENETestsVIPR2
Target ValidationVIPR2
Huge Navigator VIPR2 [HugePedia]
snp3D : Map Gene to Disease7434
BioCentury BCIQVIPR2
ClinGenVIPR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7434
Chemical/Pharm GKB GenePA37314
Clinical trialVIPR2
Miscellaneous
canSAR (ICR)VIPR2 (select the gene name)
Probes
Litterature
PubMed70 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVIPR2
EVEXVIPR2
GoPubMedVIPR2
iHOPVIPR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 27 12:01:24 CEST 2018

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