Atlas of Genetics and Cytogenetics in Oncology and Haematology


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VKORC1L1 (vitamin K epoxide reductase complex subunit 1 like 1)

Identity

Other alias-
HGNC (Hugo) VKORC1L1
LocusID (NCBI) 154807
Atlas_Id 75609
Location 7q11.21  [Link to chromosome band 7q11]
Location_base_pair Starts at 65873099 and ends at 65959563 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CFH (1q31.3) / VKORC1L1 (7q11.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)VKORC1L1   21492
Cards
Entrez_Gene (NCBI)VKORC1L1  154807  vitamin K epoxide reductase complex subunit 1 like 1
Aliases
GeneCards (Weizmann)VKORC1L1
Ensembl hg19 (Hinxton)ENSG00000196715 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000196715 [Gene_View]  chr7:65873099-65959563 [Contig_View]  VKORC1L1 [Vega]
ICGC DataPortalENSG00000196715
TCGA cBioPortalVKORC1L1
AceView (NCBI)VKORC1L1
Genatlas (Paris)VKORC1L1
WikiGenes154807
SOURCE (Princeton)VKORC1L1
Genetics Home Reference (NIH)VKORC1L1
Genomic and cartography
GoldenPath hg38 (UCSC)VKORC1L1  -     chr7:65873099-65959563 +  7q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)VKORC1L1  -     7q11.21   [Description]    (hg19-Feb_2009)
EnsemblVKORC1L1 - 7q11.21 [CytoView hg19]  VKORC1L1 - 7q11.21 [CytoView hg38]
Mapping of homologs : NCBIVKORC1L1 [Mapview hg19]  VKORC1L1 [Mapview hg38]
OMIM608838   
Gene and transcription
Genbank (Entrez)AK000750 AK001747 AK055860 AK124688 AK289522
RefSeq transcript (Entrez)NM_001284342 NM_173517
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)VKORC1L1
Cluster EST : UnigeneHs.427232 [ NCBI ]
CGAP (NCI)Hs.427232
Alternative Splicing GalleryENSG00000196715
Gene ExpressionVKORC1L1 [ NCBI-GEO ]   VKORC1L1 [ EBI - ARRAY_EXPRESS ]   VKORC1L1 [ SEEK ]   VKORC1L1 [ MEM ]
Gene Expression Viewer (FireBrowse)VKORC1L1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)154807
GTEX Portal (Tissue expression)VKORC1L1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N0U8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N0U8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N0U8
Splice isoforms : SwissVarQ8N0U8
PhosPhoSitePlusQ8N0U8
Domains : Interpro (EBI)VKOR   
Domain families : Pfam (Sanger)VKOR (PF07884)   
Domain families : Pfam (NCBI)pfam07884   
Domain families : Smart (EMBL)VKc (SM00756)  
Conserved Domain (NCBI)VKORC1L1
DMDM Disease mutations154807
Blocks (Seattle)VKORC1L1
SuperfamilyQ8N0U8
Human Protein AtlasENSG00000196715
Peptide AtlasQ8N0U8
HPRD12312
IPIIPI00166079   IPI00910375   IPI00983186   
Protein Interaction databases
DIP (DOE-UCLA)Q8N0U8
IntAct (EBI)Q8N0U8
FunCoupENSG00000196715
BioGRIDVKORC1L1
STRING (EMBL)VKORC1L1
ZODIACVKORC1L1
Ontologies - Pathways
QuickGOQ8N0U8
Ontology : AmiGOendoplasmic reticulum  endoplasmic reticulum membrane  endoplasmic reticulum membrane  integral component of membrane  peptidyl-glutamic acid carboxylation  cellular response to oxidative stress  vitamin K metabolic process  vitamin K metabolic process  vitamin-K-epoxide reductase (warfarin-sensitive) activity  vitamin-K-epoxide reductase (warfarin-sensitive) activity  quinone binding  oxidation-reduction process  
Ontology : EGO-EBIendoplasmic reticulum  endoplasmic reticulum membrane  endoplasmic reticulum membrane  integral component of membrane  peptidyl-glutamic acid carboxylation  cellular response to oxidative stress  vitamin K metabolic process  vitamin K metabolic process  vitamin-K-epoxide reductase (warfarin-sensitive) activity  vitamin-K-epoxide reductase (warfarin-sensitive) activity  quinone binding  oxidation-reduction process  
NDEx NetworkVKORC1L1
Atlas of Cancer Signalling NetworkVKORC1L1
Wikipedia pathwaysVKORC1L1
Orthology - Evolution
OrthoDB154807
GeneTree (enSembl)ENSG00000196715
Phylogenetic Trees/Animal Genes : TreeFamVKORC1L1
HOVERGENQ8N0U8
HOGENOMQ8N0U8
Homologs : HomoloGeneVKORC1L1
Homology/Alignments : Family Browser (UCSC)VKORC1L1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVKORC1L1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VKORC1L1
dbVarVKORC1L1
ClinVarVKORC1L1
1000_GenomesVKORC1L1 
Exome Variant ServerVKORC1L1
ExAC (Exome Aggregation Consortium)VKORC1L1 (select the gene name)
Genetic variants : HAPMAP154807
Genomic Variants (DGV)VKORC1L1 [DGVbeta]
DECIPHERVKORC1L1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisVKORC1L1 
Mutations
ICGC Data PortalVKORC1L1 
TCGA Data PortalVKORC1L1 
Broad Tumor PortalVKORC1L1
OASIS PortalVKORC1L1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVKORC1L1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDVKORC1L1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch VKORC1L1
DgiDB (Drug Gene Interaction Database)VKORC1L1
DoCM (Curated mutations)VKORC1L1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VKORC1L1 (select a term)
intoGenVKORC1L1
Cancer3DVKORC1L1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608838   
Orphanet
MedgenVKORC1L1
Genetic Testing Registry VKORC1L1
NextProtQ8N0U8 [Medical]
TSGene154807
GENETestsVKORC1L1
Target ValidationVKORC1L1
Huge Navigator VKORC1L1 [HugePedia]
snp3D : Map Gene to Disease154807
BioCentury BCIQVKORC1L1
ClinGenVKORC1L1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD154807
Chemical/Pharm GKB GenePA134931578
Clinical trialVKORC1L1
Miscellaneous
canSAR (ICR)VKORC1L1 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVKORC1L1
EVEXVKORC1L1
GoPubMedVKORC1L1
iHOPVKORC1L1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:43:32 CEST 2017

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