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VLDLR (very low density lipoprotein receptor)

Identity

Alias_symbol (synonym)CARMQ1
CHRMQ1
VLDLRCH
Other aliasCAMRQ1
VLDL-R
HGNC (Hugo) VLDLR
LocusID (NCBI) 7436
Atlas_Id 52167
Location 9p24.2  [Link to chromosome band 9p24]
Location_base_pair Starts at 2621774 and ends at 2656103 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)VLDLR   12698
Cards
Entrez_Gene (NCBI)VLDLR  7436  very low density lipoprotein receptor
AliasesCAMRQ1; CARMQ1; CHRMQ1; VLDL-R; 
VLDLRCH
GeneCards (Weizmann)VLDLR
Ensembl hg19 (Hinxton)ENSG00000147852 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147852 [Gene_View]  chr9:2621774-2656103 [Contig_View]  VLDLR [Vega]
ICGC DataPortalENSG00000147852
TCGA cBioPortalVLDLR
AceView (NCBI)VLDLR
Genatlas (Paris)VLDLR
WikiGenes7436
SOURCE (Princeton)VLDLR
Genetics Home Reference (NIH)VLDLR
Genomic and cartography
GoldenPath hg38 (UCSC)VLDLR  -     chr9:2621774-2656103 +  9p24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)VLDLR  -     9p24.2   [Description]    (hg19-Feb_2009)
EnsemblVLDLR - 9p24.2 [CytoView hg19]  VLDLR - 9p24.2 [CytoView hg38]
Mapping of homologs : NCBIVLDLR [Mapview hg19]  VLDLR [Mapview hg38]
OMIM192977   224050   
Gene and transcription
Genbank (Entrez)AA758887 AB208822 AK092381 AK095744 AK289527
RefSeq transcript (Entrez)NM_001018056 NM_001322225 NM_001322226 NM_003383
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)VLDLR
Cluster EST : UnigeneHs.370422 [ NCBI ]
CGAP (NCI)Hs.370422
Alternative Splicing GalleryENSG00000147852
Gene ExpressionVLDLR [ NCBI-GEO ]   VLDLR [ EBI - ARRAY_EXPRESS ]   VLDLR [ SEEK ]   VLDLR [ MEM ]
Gene Expression Viewer (FireBrowse)VLDLR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7436
GTEX Portal (Tissue expression)VLDLR
Protein : pattern, domain, 3D structure
UniProt/SwissProtP98155   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP98155  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP98155
Splice isoforms : SwissVarP98155
PhosPhoSitePlusP98155
Domaine pattern : Prosite (Expaxy)ASX_HYDROXYL (PS00010)    EGF_2 (PS01186)    EGF_3 (PS50026)    EGF_CA (PS01187)    LDLRA_1 (PS01209)    LDLRA_2 (PS50068)    LDLRB (PS51120)   
Domains : Interpro (EBI)6-blade_b-propeller_TolB-like    EGF-like_Ca-bd_dom    EGF-like_CS    EGF-like_dom    EGF-type_Asp/Asn_hydroxyl_site    EGF_Ca-bd_CS    LDLR_class-A_CS    LDLR_classB_rpt    LDrepeatLR_classA_rpt    VLDLR   
Domain families : Pfam (Sanger)EGF_CA (PF07645)    Ldl_recept_a (PF00057)    Ldl_recept_b (PF00058)   
Domain families : Pfam (NCBI)pfam07645    pfam00057    pfam00058   
Domain families : Smart (EMBL)EGF (SM00181)  EGF_CA (SM00179)  LDLa (SM00192)  LY (SM00135)  
Conserved Domain (NCBI)VLDLR
DMDM Disease mutations7436
Blocks (Seattle)VLDLR
PDB (SRS)1V9U    3DPR   
PDB (PDBSum)1V9U    3DPR   
PDB (IMB)1V9U    3DPR   
PDB (RSDB)1V9U    3DPR   
Structural Biology KnowledgeBase1V9U    3DPR   
SCOP (Structural Classification of Proteins)1V9U    3DPR   
CATH (Classification of proteins structures)1V9U    3DPR   
SuperfamilyP98155
Human Protein AtlasENSG00000147852
Peptide AtlasP98155
HPRD01895
IPIIPI00024273   IPI00219353   IPI00556192   IPI00385798   IPI00478139   
Protein Interaction databases
DIP (DOE-UCLA)P98155
IntAct (EBI)P98155
FunCoupENSG00000147852
BioGRIDVLDLR
STRING (EMBL)VLDLR
ZODIACVLDLR
Ontologies - Pathways
QuickGOP98155
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  glycoprotein binding  low-density lipoprotein receptor activity  calcium ion binding  protein binding  lysosomal membrane  plasma membrane  clathrin-coated pit  lipid transport  receptor-mediated endocytosis  signal transduction  nervous system development  memory  cholesterol metabolic process  membrane  integral component of membrane  ventral spinal cord development  very-low-density lipoprotein particle receptor activity  apolipoprotein binding  apolipoprotein binding  very-low-density lipoprotein particle binding  very-low-density lipoprotein particle  glycoprotein transport  glycoprotein transporter activity  very-low-density lipoprotein particle clearance  reelin receptor activity  reelin-mediated signaling pathway  lipoprotein metabolic process  receptor complex  positive regulation of protein kinase activity  calcium-dependent protein binding  dendrite morphogenesis  positive regulation of dendrite development  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  glycoprotein binding  low-density lipoprotein receptor activity  calcium ion binding  protein binding  lysosomal membrane  plasma membrane  clathrin-coated pit  lipid transport  receptor-mediated endocytosis  signal transduction  nervous system development  memory  cholesterol metabolic process  membrane  integral component of membrane  ventral spinal cord development  very-low-density lipoprotein particle receptor activity  apolipoprotein binding  apolipoprotein binding  very-low-density lipoprotein particle binding  very-low-density lipoprotein particle  glycoprotein transport  glycoprotein transporter activity  very-low-density lipoprotein particle clearance  reelin receptor activity  reelin-mediated signaling pathway  lipoprotein metabolic process  receptor complex  positive regulation of protein kinase activity  calcium-dependent protein binding  dendrite morphogenesis  positive regulation of dendrite development  
Pathways : BIOCARTAReelin Signaling Pathway [Genes]   
NDEx NetworkVLDLR
Atlas of Cancer Signalling NetworkVLDLR
Wikipedia pathwaysVLDLR
Orthology - Evolution
OrthoDB7436
GeneTree (enSembl)ENSG00000147852
Phylogenetic Trees/Animal Genes : TreeFamVLDLR
HOVERGENP98155
HOGENOMP98155
Homologs : HomoloGeneVLDLR
Homology/Alignments : Family Browser (UCSC)VLDLR
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVLDLR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VLDLR
dbVarVLDLR
ClinVarVLDLR
1000_GenomesVLDLR 
Exome Variant ServerVLDLR
ExAC (Exome Aggregation Consortium)VLDLR (select the gene name)
Genetic variants : HAPMAP7436
Genomic Variants (DGV)VLDLR [DGVbeta]
DECIPHERVLDLR [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisVLDLR 
Mutations
ICGC Data PortalVLDLR 
TCGA Data PortalVLDLR 
Broad Tumor PortalVLDLR
OASIS PortalVLDLR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVLDLR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDVLDLR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch VLDLR
DgiDB (Drug Gene Interaction Database)VLDLR
DoCM (Curated mutations)VLDLR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VLDLR (select a term)
intoGenVLDLR
Cancer3DVLDLR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM192977    224050   
Orphanet1777   
MedgenVLDLR
Genetic Testing Registry VLDLR
NextProtP98155 [Medical]
TSGene7436
GENETestsVLDLR
Target ValidationVLDLR
Huge Navigator VLDLR [HugePedia]
snp3D : Map Gene to Disease7436
BioCentury BCIQVLDLR
ClinGenVLDLR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7436
Chemical/Pharm GKB GenePA37317
Clinical trialVLDLR
Miscellaneous
canSAR (ICR)VLDLR (select the gene name)
Probes
Litterature
PubMed90 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVLDLR
EVEXVLDLR
GoPubMedVLDLR
iHOPVLDLR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:38:00 CEST 2017

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