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VLDLR (very low density lipoprotein receptor)

Identity

Other namesCARMQ1
CHRMQ1
VLDLRCH
HGNC (Hugo) VLDLR
LocusID (NCBI) 7436
Location 9p24.2
Location_base_pair Starts at 2621793 and ends at 2654485 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)VLDLR   12698
Cards
Entrez_Gene (NCBI)VLDLR  7436  very low density lipoprotein receptor
GeneCards (Weizmann)VLDLR
Ensembl (Hinxton)ENSG00000147852 [Gene_View]  chr9:2621793-2654485 [Contig_View]  VLDLR [Vega]
ICGC DataPortalENSG00000147852
cBioPortalVLDLR
AceView (NCBI)VLDLR
Genatlas (Paris)VLDLR
WikiGenes7436
SOURCE (Princeton)NM_001018056 NM_003383
Genomic and cartography
GoldenPath (UCSC)VLDLR  -  9p24.2   chr9:2621793-2654485 +  9p24.2   [Description]    (hg19-Feb_2009)
EnsemblVLDLR - 9p24.2 [CytoView]
Mapping of homologs : NCBIVLDLR [Mapview]
OMIM192977   224050   
Gene and transcription
Genbank (Entrez)AA758887 AB208822 AK092381 AK095744 AK289527
RefSeq transcript (Entrez)NM_001018056 NM_003383
RefSeq genomic (Entrez)AC_000141 NC_000009 NC_018920 NG_012741 NT_008413 NW_001839149 NW_004929342
Consensus coding sequences : CCDS (NCBI)VLDLR
Cluster EST : UnigeneHs.370422 [ NCBI ]
CGAP (NCI)Hs.370422
Alternative Splicing : Fast-db (Paris)GSHG0029987
Alternative Splicing GalleryENSG00000147852
Gene ExpressionVLDLR [ NCBI-GEO ]     VLDLR [ SEEK ]   VLDLR [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP98155 (Uniprot)
NextProtP98155  [Medical]
With graphics : InterProP98155
Splice isoforms : SwissVarP98155 (Swissvar)
Domaine pattern : Prosite (Expaxy)ASX_HYDROXYL (PS00010)    EGF_2 (PS01186)    EGF_3 (PS50026)    EGF_CA (PS01187)    LDLRA_1 (PS01209)    LDLRA_2 (PS50068)    LDLRB (PS51120)   
Domains : Interpro (EBI)6-blade_b-propeller_TolB-like [organisation]   EG-like_dom [organisation]   EGF-like_Ca-bd_dom [organisation]   EGF-like_CS [organisation]   EGF-type_Asp/Asn_hydroxyl_site [organisation]   EGF_Ca-bd_CS [organisation]   LDLR_class-A_CS [organisation]   LDLR_classB_rpt [organisation]   LDrepeatLR_classA_rpt [organisation]  
Related proteins : CluSTrP98155
Domain families : Pfam (Sanger)EGF_CA (PF07645)    Ldl_recept_a (PF00057)    Ldl_recept_b (PF00058)   
Domain families : Pfam (NCBI)pfam07645    pfam00057    pfam00058   
Domain families : Smart (EMBL)EGF (SM00181)  EGF_CA (SM00179)  LDLa (SM00192)  LY (SM00135)  
DMDM Disease mutations7436
Blocks (Seattle)P98155
PDB (SRS)1V9U    3DPR   
PDB (PDBSum)1V9U    3DPR   
PDB (IMB)1V9U    3DPR   
PDB (RSDB)1V9U    3DPR   
Human Protein AtlasENSG00000147852 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP98155
HPRD01895
IPIIPI00024273   IPI00219353   IPI00556192   IPI00385798   IPI00478139   
Protein Interaction databases
DIP (DOE-UCLA)P98155
IntAct (EBI)P98155
FunCoupENSG00000147852
BioGRIDVLDLR
InParanoidP98155
Interologous Interaction database P98155
IntegromeDBVLDLR
STRING (EMBL)VLDLR
Ontologies - Pathways
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  glycoprotein binding  low-density lipoprotein receptor activity  calcium ion binding  protein binding  plasma membrane  coated pit  lipid transport  receptor-mediated endocytosis  signal transduction  nervous system development  memory  cholesterol metabolic process  membrane  integral component of membrane  ventral spinal cord development  very-low-density lipoprotein particle receptor activity  apolipoprotein binding  apolipoprotein binding  very-low-density lipoprotein particle binding  very-low-density lipoprotein particle  glycoprotein transport  glycoprotein transporter activity  very-low-density lipoprotein particle clearance  reelin receptor activity  reelin-mediated signaling pathway  receptor complex  positive regulation of protein kinase activity  calcium-dependent protein binding  positive regulation of dendrite development  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  glycoprotein binding  low-density lipoprotein receptor activity  calcium ion binding  protein binding  plasma membrane  coated pit  lipid transport  receptor-mediated endocytosis  signal transduction  nervous system development  memory  cholesterol metabolic process  membrane  integral component of membrane  ventral spinal cord development  very-low-density lipoprotein particle receptor activity  apolipoprotein binding  apolipoprotein binding  very-low-density lipoprotein particle binding  very-low-density lipoprotein particle  glycoprotein transport  glycoprotein transporter activity  very-low-density lipoprotein particle clearance  reelin receptor activity  reelin-mediated signaling pathway  receptor complex  positive regulation of protein kinase activity  calcium-dependent protein binding  positive regulation of dendrite development  
Pathways : BIOCARTAReelin Signaling Pathway [Genes]   
Protein Interaction DatabaseVLDLR
Wikipedia pathwaysVLDLR
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)VLDLR
snp3D : Map Gene to Disease7436
SNP (GeneSNP Utah)VLDLR
SNP : HGBaseVLDLR
Genetic variants : HAPMAPVLDLR
Exome VariantVLDLR
1000_GenomesVLDLR 
ICGC programENSG00000147852 
Somatic Mutations in Cancer : COSMICVLDLR 
CONAN: Copy Number AnalysisVLDLR 
Mutations and Diseases : HGMDVLDLR
Mutations and Diseases : intOGenVLDLR
Genomic VariantsVLDLR  VLDLR [DGVbeta]
dbVarVLDLR
ClinVarVLDLR
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM192977    224050   
MedgenVLDLR
GENETestsVLDLR
Disease Genetic AssociationVLDLR
Huge Navigator VLDLR [HugePedia]  VLDLR [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneVLDLR
Homology/Alignments : Family Browser (UCSC)VLDLR
Phylogenetic Trees/Animal Genes : TreeFamVLDLR
Chemical/Protein Interactions : CTD7436
Chemical/Pharm GKB GenePA37317
Clinical trialVLDLR
Cancer Resource (Charite)ENSG00000147852
Other databases
Probes
Litterature
PubMed87 Pubmed reference(s) in Entrez
CoreMineVLDLR
iHOPVLDLR
OncoSearchVLDLR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 17:10:06 CEST 2014

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