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VNN2 (vanin 2)

Identity

Alias (NCBI)FOAP-4
GPI-80
HGNC (Hugo) VNN2
HGNC Alias symbFOAP-4
GPI-80
HGNC Alias namepantetheinase
LocusID (NCBI) 8875
Atlas_Id 57785
Location 6q23.2  [Link to chromosome band 6q23]
Location_base_pair Starts at 132743870 and ends at 132763459 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)VNN2   12706
Cards
Entrez_Gene (NCBI)VNN2  8875  vanin 2
AliasesFOAP-4; GPI-80
GeneCards (Weizmann)VNN2
Ensembl hg19 (Hinxton)ENSG00000112303 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112303 [Gene_View]  ENSG00000112303 [Sequence]  chr6:132743870-132763459 [Contig_View]  VNN2 [Vega]
ICGC DataPortalENSG00000112303
TCGA cBioPortalVNN2
AceView (NCBI)VNN2
Genatlas (Paris)VNN2
WikiGenes8875
SOURCE (Princeton)VNN2
Genetics Home Reference (NIH)VNN2
Genomic and cartography
GoldenPath hg38 (UCSC)VNN2  -     chr6:132743870-132763459 -  6q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)VNN2  -     6q23.2   [Description]    (hg19-Feb_2009)
GoldenPathVNN2 - 6q23.2 [CytoView hg19]  VNN2 - 6q23.2 [CytoView hg38]
ImmunoBaseENSG00000112303
genome Data Viewer NCBIVNN2 [Mapview hg19]  
OMIM603571   
Gene and transcription
Genbank (Entrez)AB026705 AB435062 AB435063 AB435064 AB435065
RefSeq transcript (Entrez)NM_001242350 NM_004665 NM_078488
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)VNN2
Alternative Splicing GalleryENSG00000112303
Gene ExpressionVNN2 [ NCBI-GEO ]   VNN2 [ EBI - ARRAY_EXPRESS ]   VNN2 [ SEEK ]   VNN2 [ MEM ]
Gene Expression Viewer (FireBrowse)VNN2 [ Firebrowse - Broad ]
GenevisibleExpression of VNN2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8875
GTEX Portal (Tissue expression)VNN2
Human Protein AtlasENSG00000112303-VNN2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95498   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95498  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95498
Splice isoforms : SwissVarO95498
Catalytic activity : Enzyme3.5.1.92 [ Enzyme-Expasy ]   3.5.1.923.5.1.92 [ IntEnz-EBI ]   3.5.1.92 [ BRENDA ]   3.5.1.92 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusO95498
Domaine pattern : Prosite (Expaxy)CN_HYDROLASE (PS50263)   
Domains : Interpro (EBI)Biotinidase-like_euk    Biotinidase/VNN    C-N_Hydrolase    C-N_Hydrolase_sf   
Domain families : Pfam (Sanger)CN_hydrolase (PF00795)   
Domain families : Pfam (NCBI)pfam00795   
Conserved Domain (NCBI)VNN2
DMDM Disease mutations8875
Blocks (Seattle)VNN2
SuperfamilyO95498
Human Protein Atlas [tissue]ENSG00000112303-VNN2 [tissue]
Peptide AtlasO95498
IPIIPI00030872   IPI00954928   IPI00895868   IPI00895848   IPI00954960   IPI00973754   IPI00072246   IPI00984343   IPI00983310   IPI00973813   IPI00977466   IPI00982296   IPI00981527   IPI00981260   
Protein Interaction databases
DIP (DOE-UCLA)O95498
IntAct (EBI)O95498
FunCoupENSG00000112303
BioGRIDVNN2
STRING (EMBL)VNN2
ZODIACVNN2
Ontologies - Pathways
QuickGOO95498
Ontology : AmiGOextracellular region  plasma membrane  pantothenate metabolic process  pantothenate metabolic process  pantothenate metabolic process  pantetheine hydrolase activity  pantetheine hydrolase activity  anchored component of membrane  
Ontology : EGO-EBIextracellular region  plasma membrane  pantothenate metabolic process  pantothenate metabolic process  pantothenate metabolic process  pantetheine hydrolase activity  pantetheine hydrolase activity  anchored component of membrane  
Pathways : KEGGPantothenate and CoA biosynthesis   
NDEx NetworkVNN2
Atlas of Cancer Signalling NetworkVNN2
Wikipedia pathwaysVNN2
Orthology - Evolution
OrthoDB8875
GeneTree (enSembl)ENSG00000112303
Phylogenetic Trees/Animal Genes : TreeFamVNN2
HOGENOMO95498
Homologs : HomoloGeneVNN2
Homology/Alignments : Family Browser (UCSC)VNN2
Gene fusions - Rearrangements
Fusion : QuiverVNN2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVNN2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VNN2
dbVarVNN2
ClinVarVNN2
MonarchVNN2
1000_GenomesVNN2 
Exome Variant ServerVNN2
GNOMAD BrowserENSG00000112303
Varsome BrowserVNN2
Genetic variants : HAPMAP8875
Genomic Variants (DGV)VNN2 [DGVbeta]
DECIPHERVNN2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisVNN2 
Mutations
ICGC Data PortalVNN2 
TCGA Data PortalVNN2 
Broad Tumor PortalVNN2
OASIS PortalVNN2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVNN2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DVNN2
Mutations and Diseases : HGMDVNN2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch VNN2
DgiDB (Drug Gene Interaction Database)VNN2
DoCM (Curated mutations)VNN2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VNN2 (select a term)
intoGenVNN2
Cancer3DVNN2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603571   
Orphanet
DisGeNETVNN2
MedgenVNN2
Genetic Testing Registry VNN2
NextProtO95498 [Medical]
TSGene8875
GENETestsVNN2
Target ValidationVNN2
Huge Navigator VNN2 [HugePedia]
snp3D : Map Gene to Disease8875
BioCentury BCIQVNN2
ClinGenVNN2
Clinical trials, drugs, therapy
Protein Interactions : CTD8875
Pharm GKB GenePA37322
Clinical trialVNN2
Miscellaneous
canSAR (ICR)VNN2 (select the gene name)
HarmonizomeVNN2
DataMed IndexVNN2
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVNN2
EVEXVNN2
GoPubMedVNN2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 14 14:38:47 CEST 2020
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