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VOPP1 (VOPP1, WBP1/VOPP1 family member)

Identity

Alias_symbol (synonym)ECop
GASP
FLJ20532
DKFZp564K0822
Other aliasECOP
WBP1L2
HGNC (Hugo) VOPP1
LocusID (NCBI) 81552
Atlas_Id 51092
Location 7p11.2  [Link to chromosome band 7p11]
Location_base_pair Starts at 55470608 and ends at 55572520 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EGFR (7p11.2) / VOPP1 (7p11.2)VOPP1 (7p11.2) / GRB10 (7p12.1)VOPP1 (7p11.2) / IL22 (12q15)
VOPP1 (7p11.2) / VOPP1 (7p11.2)VOPP1 (7p11.2) / ZNF713 (7p11.2)ZNF679 (7q11.21) / VOPP1 (7p11.2)
ZNF679 7q11.21 / VOPP1 7p11.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 5 ]
  Lung: Translocations in Squamous Cell Carcinoma
EGFR/VOPP1 (7p11)
t(7;7)(p11;p12) VOPP1/GRB10
t(7;7)(p11;q11) ZNF679/VOPP1
t(7;12)(p11;q15) VOPP1/IL22


External links

Nomenclature
HGNC (Hugo)VOPP1   34518
Cards
Entrez_Gene (NCBI)VOPP1  81552  VOPP1, WBP1/VOPP1 family member
AliasesECOP; GASP; WBP1L2
GeneCards (Weizmann)VOPP1
Ensembl hg19 (Hinxton)ENSG00000154978 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000154978 [Gene_View]  ENSG00000154978 [Sequence]  chr7:55470608-55572520 [Contig_View]  VOPP1 [Vega]
ICGC DataPortalENSG00000154978
TCGA cBioPortalVOPP1
AceView (NCBI)VOPP1
Genatlas (Paris)VOPP1
WikiGenes81552
SOURCE (Princeton)VOPP1
Genetics Home Reference (NIH)VOPP1
Genomic and cartography
GoldenPath hg38 (UCSC)VOPP1  -     chr7:55470608-55572520 -  7p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)VOPP1  -     7p11.2   [Description]    (hg19-Feb_2009)
EnsemblVOPP1 - 7p11.2 [CytoView hg19]  VOPP1 - 7p11.2 [CytoView hg38]
Mapping of homologs : NCBIVOPP1 [Mapview hg19]  VOPP1 [Mapview hg38]
OMIM611915   
Gene and transcription
Genbank (Entrez)AB097004 AF395824 AK000539 AK075391 AK090825
RefSeq transcript (Entrez)NM_001284282 NM_001284283 NM_001284284 NM_001321242 NM_001321243 NM_001321244 NM_001321246 NM_001321247 NM_001321248 NM_001321249 NM_001321250 NM_001321251 NM_030796
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)VOPP1
Cluster EST : UnigeneHs.680358 [ NCBI ]
CGAP (NCI)Hs.680358
Alternative Splicing GalleryENSG00000154978
Gene ExpressionVOPP1 [ NCBI-GEO ]   VOPP1 [ EBI - ARRAY_EXPRESS ]   VOPP1 [ SEEK ]   VOPP1 [ MEM ]
Gene Expression Viewer (FireBrowse)VOPP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81552
GTEX Portal (Tissue expression)VOPP1
Human Protein AtlasENSG00000154978-VOPP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96AW1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96AW1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96AW1
Splice isoforms : SwissVarQ96AW1
PhosPhoSitePlusQ96AW1
Domains : Interpro (EBI)VOPP1   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)VOPP1
DMDM Disease mutations81552
Blocks (Seattle)VOPP1
SuperfamilyQ96AW1
Human Protein Atlas [tissue]ENSG00000154978-VOPP1 [tissue]
Peptide AtlasQ96AW1
HPRD08526
IPIIPI00414382   IPI00924558   IPI00981808   IPI00927369   IPI00927148   IPI00926899   IPI00926660   IPI00926438   IPI00926213   IPI01010969   IPI00925761   IPI00925502   IPI00925043   
Protein Interaction databases
DIP (DOE-UCLA)Q96AW1
IntAct (EBI)Q96AW1
FunCoupENSG00000154978
BioGRIDVOPP1
STRING (EMBL)VOPP1
ZODIACVOPP1
Ontologies - Pathways
QuickGOQ96AW1
Ontology : AmiGOendosome  transcription, DNA-templated  regulation of transcription, DNA-templated  cytoplasmic vesicle membrane  integral component of organelle membrane  integral component of organelle membrane  
Ontology : EGO-EBIendosome  transcription, DNA-templated  regulation of transcription, DNA-templated  cytoplasmic vesicle membrane  integral component of organelle membrane  integral component of organelle membrane  
NDEx NetworkVOPP1
Atlas of Cancer Signalling NetworkVOPP1
Wikipedia pathwaysVOPP1
Orthology - Evolution
OrthoDB81552
GeneTree (enSembl)ENSG00000154978
Phylogenetic Trees/Animal Genes : TreeFamVOPP1
HOVERGENQ96AW1
HOGENOMQ96AW1
Homologs : HomoloGeneVOPP1
Homology/Alignments : Family Browser (UCSC)VOPP1
Gene fusions - Rearrangements
Fusion : MitelmanEGFR/VOPP1 [7p11.2/7p11.2]  [t(7;7)(p11;p11)]  
Fusion : MitelmanVOPP1/GRB10 [7p11.2/7p12.1]  [t(7;7)(p11;p12)]  
Fusion : MitelmanVOPP1/IL22 [7p11.2/12q15]  [t(7;12)(p11;q15)]  
Fusion : MitelmanZNF679/VOPP1 [7q11.21/7p11.2]  [t(7;7)(p11;q11)]  
Fusion PortalZNF679 7q11.21 VOPP1 7p11.2 LUAD
Fusion : QuiverVOPP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVOPP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VOPP1
dbVarVOPP1
ClinVarVOPP1
1000_GenomesVOPP1 
Exome Variant ServerVOPP1
ExAC (Exome Aggregation Consortium)ENSG00000154978
GNOMAD BrowserENSG00000154978
Varsome BrowserVOPP1
Genetic variants : HAPMAP81552
Genomic Variants (DGV)VOPP1 [DGVbeta]
DECIPHERVOPP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisVOPP1 
Mutations
ICGC Data PortalVOPP1 
TCGA Data PortalVOPP1 
Broad Tumor PortalVOPP1
OASIS PortalVOPP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVOPP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDVOPP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch VOPP1
DgiDB (Drug Gene Interaction Database)VOPP1
DoCM (Curated mutations)VOPP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VOPP1 (select a term)
intoGenVOPP1
Cancer3DVOPP1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611915   
Orphanet
DisGeNETVOPP1
MedgenVOPP1
Genetic Testing Registry VOPP1
NextProtQ96AW1 [Medical]
TSGene81552
GENETestsVOPP1
Target ValidationVOPP1
Huge Navigator VOPP1 [HugePedia]
snp3D : Map Gene to Disease81552
BioCentury BCIQVOPP1
ClinGenVOPP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD81552
Chemical/Pharm GKB GenePA165618503
Clinical trialVOPP1
Miscellaneous
canSAR (ICR)VOPP1 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVOPP1
EVEXVOPP1
GoPubMedVOPP1
iHOPVOPP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 27 12:01:26 CEST 2018

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