Atlas of Genetics and Cytogenetics in Oncology and Haematology


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VPS25 (vacuolar protein sorting 25 homolog (S. cerevisiae))

Identity

Alias_namesvacuolar protein sorting 25 (yeast)
vacuolar protein sorting 25 homolog (S. cerevisiae)
Alias_symbol (synonym)MGC10540
EAP20
DERP9
Other aliasFAP20
HGNC (Hugo) VPS25
LocusID (NCBI) 84313
Atlas_Id 75629
Location 17q21.31  [Link to chromosome band 17q21]
Location_base_pair Starts at 40925454 and ends at 40931618 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ZNF335 (20q13.12) / VPS25 (17q21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)VPS25   28122
Cards
Entrez_Gene (NCBI)VPS25  84313  vacuolar protein sorting 25 homolog (S. cerevisiae)
AliasesDERP9; EAP20; FAP20
GeneCards (Weizmann)VPS25
Ensembl hg19 (Hinxton)ENSG00000131475 [Gene_View]  chr17:40925454-40931618 [Contig_View]  VPS25 [Vega]
Ensembl hg38 (Hinxton)ENSG00000131475 [Gene_View]  chr17:40925454-40931618 [Contig_View]  VPS25 [Vega]
ICGC DataPortalENSG00000131475
TCGA cBioPortalVPS25
AceView (NCBI)VPS25
Genatlas (Paris)VPS25
WikiGenes84313
SOURCE (Princeton)VPS25
Genetics Home Reference (NIH)VPS25
Genomic and cartography
GoldenPath hg19 (UCSC)VPS25  -     chr17:40925454-40931618 +  17q21.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)VPS25  -     17q21.31   [Description]    (hg38-Dec_2013)
EnsemblVPS25 - 17q21.31 [CytoView hg19]  VPS25 - 17q21.31 [CytoView hg38]
Mapping of homologs : NCBIVPS25 [Mapview hg19]  VPS25 [Mapview hg38]
OMIM610907   
Gene and transcription
Genbank (Entrez)AB014763 AK312092 BC006282 BU630023 HQ448303
RefSeq transcript (Entrez)NM_032353
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)VPS25
Cluster EST : UnigeneHs.500165 [ NCBI ]
CGAP (NCI)Hs.500165
Alternative Splicing GalleryENSG00000131475
Gene ExpressionVPS25 [ NCBI-GEO ]   VPS25 [ EBI - ARRAY_EXPRESS ]   VPS25 [ SEEK ]   VPS25 [ MEM ]
Gene Expression Viewer (FireBrowse)VPS25 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84313
GTEX Portal (Tissue expression)VPS25
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BRG1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BRG1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BRG1
Splice isoforms : SwissVarQ9BRG1
PhosPhoSitePlusQ9BRG1
Domains : Interpro (EBI)ESCRT-II_cplx_vps25-sub    ESCRT-II_cplx_Vps25-sub_N    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)ESCRT-II (PF05871)   
Domain families : Pfam (NCBI)pfam05871   
Conserved Domain (NCBI)VPS25
DMDM Disease mutations84313
Blocks (Seattle)VPS25
PDB (SRS)2ZME    3CUQ    3HTU   
PDB (PDBSum)2ZME    3CUQ    3HTU   
PDB (IMB)2ZME    3CUQ    3HTU   
PDB (RSDB)2ZME    3CUQ    3HTU   
Structural Biology KnowledgeBase2ZME    3CUQ    3HTU   
SCOP (Structural Classification of Proteins)2ZME    3CUQ    3HTU   
CATH (Classification of proteins structures)2ZME    3CUQ    3HTU   
SuperfamilyQ9BRG1
Human Protein AtlasENSG00000131475
Peptide AtlasQ9BRG1
HPRD14396
IPIIPI00031655   
Protein Interaction databases
DIP (DOE-UCLA)Q9BRG1
IntAct (EBI)Q9BRG1
FunCoupENSG00000131475
BioGRIDVPS25
STRING (EMBL)VPS25
ZODIACVPS25
Ontologies - Pathways
QuickGOQ9BRG1
Ontology : AmiGOESCRT II complex  structural molecule activity  protein binding  nucleus  nucleoplasm  nucleolus  cytoplasm  mitochondrion  cytosol  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  endosome membrane  endosomal transport  protein homodimerization activity  protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway  protein N-terminus binding  membrane organization  extracellular exosome  regulation of viral life cycle  
Ontology : EGO-EBIESCRT II complex  structural molecule activity  protein binding  nucleus  nucleoplasm  nucleolus  cytoplasm  mitochondrion  cytosol  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  endosome membrane  endosomal transport  protein homodimerization activity  protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway  protein N-terminus binding  membrane organization  extracellular exosome  regulation of viral life cycle  
Pathways : KEGGEndocytosis   
NDEx NetworkVPS25
Atlas of Cancer Signalling NetworkVPS25
Wikipedia pathwaysVPS25
Orthology - Evolution
OrthoDB84313
GeneTree (enSembl)ENSG00000131475
Phylogenetic Trees/Animal Genes : TreeFamVPS25
HOVERGENQ9BRG1
HOGENOMQ9BRG1
Homologs : HomoloGeneVPS25
Homology/Alignments : Family Browser (UCSC)VPS25
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVPS25 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VPS25
dbVarVPS25
ClinVarVPS25
1000_GenomesVPS25 
Exome Variant ServerVPS25
ExAC (Exome Aggregation Consortium)VPS25 (select the gene name)
Genetic variants : HAPMAP84313
Genomic Variants (DGV)VPS25 [DGVbeta]
DECIPHER (Syndromes)17:40925454-40931618  ENSG00000131475
CONAN: Copy Number AnalysisVPS25 
Mutations
ICGC Data PortalVPS25 
TCGA Data PortalVPS25 
Broad Tumor PortalVPS25
OASIS PortalVPS25 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVPS25  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDVPS25
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch VPS25
DgiDB (Drug Gene Interaction Database)VPS25
DoCM (Curated mutations)VPS25 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VPS25 (select a term)
intoGenVPS25
Cancer3DVPS25(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610907   
Orphanet
MedgenVPS25
Genetic Testing Registry VPS25
NextProtQ9BRG1 [Medical]
TSGene84313
GENETestsVPS25
Huge Navigator VPS25 [HugePedia]
snp3D : Map Gene to Disease84313
BioCentury BCIQVPS25
ClinGenVPS25
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84313
Chemical/Pharm GKB GenePA142670614
Clinical trialVPS25
Miscellaneous
canSAR (ICR)VPS25 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVPS25
EVEXVPS25
GoPubMedVPS25
iHOPVPS25
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:51:18 CET 2017

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