VPS25 (vacuolar protein sorting 25 homolog)

2014-11-01  

Identity

HGNC
LOCATION
17q21.2
LOCUSID
ALIAS
DERP9,EAP20,FAP20
FUSION GENES

Other Information

Locus ID:

NCBI: 84313
MIM: 610907
HGNC: 28122
Ensembl: ENSG00000131475

Variants:

dbSNP: 84313
ClinVar: 84313
TCGA: ENSG00000131475
COSMIC: VPS25

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000131475ENST00000253794Q9BRG1
ENSG00000131475ENST00000253794A0A024R1X3
ENSG00000131475ENST00000589520K7EKV4
ENSG00000131475ENST00000589577K7EP45
ENSG00000131475ENST00000590339K7ENE3

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144
ESCRT-II complexKEGGhsa_M00410
ESCRT-II complexKEGGM00410
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Endosomal Sorting Complex Required For Transport (ESCRT)REACTOMER-HSA-917729

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
163713482006Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII.69
196866842009Structure and function of the ESCRT-II-III interface in multivesicular body biogenesis.54
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11

Citation

Dessen P

VPS25 (vacuolar protein sorting 25 homolog)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75629/vps25