Atlas of Genetics and Cytogenetics in Oncology and Haematology


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VPS26A (VPS26, retromer complex component A)

Identity

Alias (NCBI)HB58
Hbeta58
PEP8A
VPS26
HGNC (Hugo) VPS26A
HGNC Alias symbHbeta58
PEP8A
HGNC Previous nameVPS26
HGNC Previous namevacuolar protein sorting 26 (yeast homolog)
 vacuolar protein sorting 26 homolog A (S. pombe)
LocusID (NCBI) 9559
Atlas_Id 75630
Location 10q22.1  [Link to chromosome band 10q22]
Location_base_pair Starts at 69124178 and ends at 69174412 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GLUD1 (10q23.2) / VPS26A (10q22.1)SPATA1 (1p22.3) / VPS26A (10q22.1)SUPV3L1 (10q22.1) / VPS26A (10q22.1)
TSPAN15 (10q22.1) / VPS26A (10q22.1)VPS26A (10q22.1) / ATAD1 (10q23.31)VPS26A (10q22.1) / GDAP1L1 (20q13.12)
VPS26A (10q22.1) / GYS1 (19q13.33)VPS26A (10q22.1) / KIF1BP (10q22.1)VPS26A (10q22.1) / NIPBL (5p13.2)
VPS26A (10q22.1) / VPS26A (10q22.1)TSPAN15 VPS26ASUPV3L1 VPS26A

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)VPS26A   12711
Cards
Entrez_Gene (NCBI)VPS26A    VPS26, retromer complex component A
AliasesHB58; Hbeta58; PEP8A; VPS26
GeneCards (Weizmann)VPS26A
Ensembl hg19 (Hinxton)ENSG00000122958 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000122958 [Gene_View]  ENSG00000122958 [Sequence]  chr10:69124178-69174412 [Contig_View]  VPS26A [Vega]
ICGC DataPortalENSG00000122958
TCGA cBioPortalVPS26A
AceView (NCBI)VPS26A
Genatlas (Paris)VPS26A
SOURCE (Princeton)VPS26A
Genetics Home Reference (NIH)VPS26A
Genomic and cartography
GoldenPath hg38 (UCSC)VPS26A  -     chr10:69124178-69174412 +  10q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)VPS26A  -     10q22.1   [Description]    (hg19-Feb_2009)
GoldenPathVPS26A - 10q22.1 [CytoView hg19]  VPS26A - 10q22.1 [CytoView hg38]
ImmunoBaseENSG00000122958
Genome Data Viewer NCBIVPS26A [Mapview hg19]  
OMIM605506   
Gene and transcription
Genbank (Entrez)AF054179 AF175266 AK022992 AK290536 AK297142
RefSeq transcript (Entrez)NM_001035260 NM_001318944 NM_001318945 NM_001318946 NM_004896
Consensus coding sequences : CCDS (NCBI)VPS26A
Gene ExpressionVPS26A [ NCBI-GEO ]   VPS26A [ EBI - ARRAY_EXPRESS ]   VPS26A [ SEEK ]   VPS26A [ MEM ]
Gene Expression Viewer (FireBrowse)VPS26A [ Firebrowse - Broad ]
GenevisibleExpression of VPS26A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9559
GTEX Portal (Tissue expression)VPS26A
Human Protein AtlasENSG00000122958-VPS26A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75436   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75436  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75436
PhosPhoSitePlusO75436
Domains : Interpro (EBI)Arrestin_C    Vps26-related   
Domain families : Pfam (Sanger)Vps26 (PF03643)   
Domain families : Pfam (NCBI)pfam03643   
Conserved Domain (NCBI)VPS26A
PDB (RSDB)2FAU    5F0J    5F0L    5F0M    5F0P   
PDB Europe2FAU    5F0J    5F0L    5F0M    5F0P   
PDB (PDBSum)2FAU    5F0J    5F0L    5F0M    5F0P   
PDB (IMB)2FAU    5F0J    5F0L    5F0M    5F0P   
Structural Biology KnowledgeBase2FAU    5F0J    5F0L    5F0M    5F0P   
SCOP (Structural Classification of Proteins)2FAU    5F0J    5F0L    5F0M    5F0P   
CATH (Classification of proteins structures)2FAU    5F0J    5F0L    5F0M    5F0P   
SuperfamilyO75436
AlphaFold pdb e-kbO75436   
Human Protein Atlas [tissue]ENSG00000122958-VPS26A [tissue]
HPRD08385
Protein Interaction databases
DIP (DOE-UCLA)O75436
IntAct (EBI)O75436
BioGRIDVPS26A
STRING (EMBL)VPS26A
ZODIACVPS26A
Ontologies - Pathways
QuickGOO75436
Ontology : AmiGOprotein binding  lysosome  endosome  endosome  early endosome  cytosol  intracellular protein transport  endosome membrane  Wnt signaling pathway  regulation of macroautophagy  retromer complex  retromer complex  retromer complex  retromer, cargo-selective complex  retromer, cargo-selective complex  vesicle  endocytic recycling  retrograde transport, endosome to Golgi  retrograde transport, endosome to Golgi  retrograde transport, endosome to Golgi  tubular endosome  
Ontology : EGO-EBIprotein binding  lysosome  endosome  endosome  early endosome  cytosol  intracellular protein transport  endosome membrane  Wnt signaling pathway  regulation of macroautophagy  retromer complex  retromer complex  retromer complex  retromer, cargo-selective complex  retromer, cargo-selective complex  vesicle  endocytic recycling  retrograde transport, endosome to Golgi  retrograde transport, endosome to Golgi  retrograde transport, endosome to Golgi  tubular endosome  
NDEx NetworkVPS26A
Atlas of Cancer Signalling NetworkVPS26A
Wikipedia pathwaysVPS26A
Orthology - Evolution
OrthoDB9559
GeneTree (enSembl)ENSG00000122958
Phylogenetic Trees/Animal Genes : TreeFamVPS26A
Homologs : HomoloGeneVPS26A
Homology/Alignments : Family Browser (UCSC)VPS26A
Gene fusions - Rearrangements
Fusion : QuiverVPS26A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVPS26A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VPS26A
dbVarVPS26A
ClinVarVPS26A
MonarchVPS26A
1000_GenomesVPS26A 
Exome Variant ServerVPS26A
GNOMAD BrowserENSG00000122958
Varsome BrowserVPS26A
ACMGVPS26A variants
VarityO75436
Genomic Variants (DGV)VPS26A [DGVbeta]
DECIPHERVPS26A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisVPS26A 
Mutations
ICGC Data PortalVPS26A 
TCGA Data PortalVPS26A 
Broad Tumor PortalVPS26A
OASIS PortalVPS26A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVPS26A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DVPS26A
Mutations and Diseases : HGMDVPS26A
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaVPS26A
DgiDB (Drug Gene Interaction Database)VPS26A
DoCM (Curated mutations)VPS26A
CIViC (Clinical Interpretations of Variants in Cancer)VPS26A
Cancer3DVPS26A
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605506   
Orphanet
DisGeNETVPS26A
MedgenVPS26A
Genetic Testing Registry VPS26A
NextProtO75436 [Medical]
GENETestsVPS26A
Target ValidationVPS26A
Huge Navigator VPS26A [HugePedia]
ClinGenVPS26A
Clinical trials, drugs, therapy
MyCancerGenomeVPS26A
Protein Interactions : CTDVPS26A
Pharm GKB GenePA37326
PharosO75436
Clinical trialVPS26A
Miscellaneous
canSAR (ICR)VPS26A
HarmonizomeVPS26A
DataMed IndexVPS26A
Probes
Litterature
PubMed105 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXVPS26A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:28:12 CEST 2021

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