Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

VPS33A (VPS33A, CORVET/HOPS core subunit)

Identity

Alias_namesvacuolar protein sorting 33A (yeast)
vacuolar protein sorting 33 homolog A (S. cerevisiae)
Other aliasMPSPS
HGNC (Hugo) VPS33A
LocusID (NCBI) 65082
Atlas_Id 52644
Location 12q24.31  [Link to chromosome band 12q24]
Location_base_pair Starts at 122231547 and ends at 122266521 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
VPS33A (12q24.31) / MPHOSPH9 (12q24.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)VPS33A   18179
Cards
Entrez_Gene (NCBI)VPS33A  65082  VPS33A, CORVET/HOPS core subunit
AliasesMPSPS
GeneCards (Weizmann)VPS33A
Ensembl hg19 (Hinxton)ENSG00000139719 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000139719 [Gene_View]  chr12:122231547-122266521 [Contig_View]  VPS33A [Vega]
ICGC DataPortalENSG00000139719
TCGA cBioPortalVPS33A
AceView (NCBI)VPS33A
Genatlas (Paris)VPS33A
WikiGenes65082
SOURCE (Princeton)VPS33A
Genetics Home Reference (NIH)VPS33A
Genomic and cartography
GoldenPath hg38 (UCSC)VPS33A  -     chr12:122231547-122266521 -  12q24.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)VPS33A  -     12q24.31   [Description]    (hg19-Feb_2009)
EnsemblVPS33A - 12q24.31 [CytoView hg19]  VPS33A - 12q24.31 [CytoView hg38]
Mapping of homologs : NCBIVPS33A [Mapview hg19]  VPS33A [Mapview hg38]
OMIM610034   617303   
Gene and transcription
Genbank (Entrez)AF439857 AK026048 AK026840 AK315545 BC016617
RefSeq transcript (Entrez)NM_022916
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)VPS33A
Cluster EST : UnigeneHs.592009 [ NCBI ]
CGAP (NCI)Hs.592009
Alternative Splicing GalleryENSG00000139719
Gene ExpressionVPS33A [ NCBI-GEO ]   VPS33A [ EBI - ARRAY_EXPRESS ]   VPS33A [ SEEK ]   VPS33A [ MEM ]
Gene Expression Viewer (FireBrowse)VPS33A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)65082
GTEX Portal (Tissue expression)VPS33A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96AX1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96AX1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96AX1
Splice isoforms : SwissVarQ96AX1
PhosPhoSitePlusQ96AX1
Domains : Interpro (EBI)Sec-1-like_dom2    Sec1-like    VPS33   
Domain families : Pfam (Sanger)Sec1 (PF00995)   
Domain families : Pfam (NCBI)pfam00995   
Conserved Domain (NCBI)VPS33A
DMDM Disease mutations65082
Blocks (Seattle)VPS33A
PDB (SRS)4BX8    4BX9   
PDB (PDBSum)4BX8    4BX9   
PDB (IMB)4BX8    4BX9   
PDB (RSDB)4BX8    4BX9   
Structural Biology KnowledgeBase4BX8    4BX9   
SCOP (Structural Classification of Proteins)4BX8    4BX9   
CATH (Classification of proteins structures)4BX8    4BX9   
SuperfamilyQ96AX1
Human Protein AtlasENSG00000139719
Peptide AtlasQ96AX1
HPRD15651
IPIIPI00073179   IPI00795814   IPI01014453   IPI01014346   
Protein Interaction databases
DIP (DOE-UCLA)Q96AX1
IntAct (EBI)Q96AX1
FunCoupENSG00000139719
BioGRIDVPS33A
STRING (EMBL)VPS33A
ZODIACVPS33A
Ontologies - Pathways
QuickGOQ96AX1
Ontology : AmiGOprotein binding  lysosome  lysosomal membrane  early endosome  late endosome  autophagosome  vesicle docking involved in exocytosis  endosome to lysosome transport  protein transport  vesicle-mediated transport  AP-3 adaptor complex  clathrin-coated vesicle  platelet formation  HOPS complex  HOPS complex  late endosome membrane  melanosome localization  lysosome localization  regulation of lysosomal lumen pH  regulation of developmental pigmentation  perinuclear region of cytoplasm  clathrin complex  autophagosome maturation  
Ontology : EGO-EBIprotein binding  lysosome  lysosomal membrane  early endosome  late endosome  autophagosome  vesicle docking involved in exocytosis  endosome to lysosome transport  protein transport  vesicle-mediated transport  AP-3 adaptor complex  clathrin-coated vesicle  platelet formation  HOPS complex  HOPS complex  late endosome membrane  melanosome localization  lysosome localization  regulation of lysosomal lumen pH  regulation of developmental pigmentation  perinuclear region of cytoplasm  clathrin complex  autophagosome maturation  
NDEx NetworkVPS33A
Atlas of Cancer Signalling NetworkVPS33A
Wikipedia pathwaysVPS33A
Orthology - Evolution
OrthoDB65082
GeneTree (enSembl)ENSG00000139719
Phylogenetic Trees/Animal Genes : TreeFamVPS33A
HOVERGENQ96AX1
HOGENOMQ96AX1
Homologs : HomoloGeneVPS33A
Homology/Alignments : Family Browser (UCSC)VPS33A
Gene fusions - Rearrangements
Fusion : MitelmanVPS33A/MPHOSPH9 [12q24.31/12q24.31]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVPS33A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VPS33A
dbVarVPS33A
ClinVarVPS33A
1000_GenomesVPS33A 
Exome Variant ServerVPS33A
ExAC (Exome Aggregation Consortium)VPS33A (select the gene name)
Genetic variants : HAPMAP65082
Genomic Variants (DGV)VPS33A [DGVbeta]
DECIPHERVPS33A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisVPS33A 
Mutations
ICGC Data PortalVPS33A 
TCGA Data PortalVPS33A 
Broad Tumor PortalVPS33A
OASIS PortalVPS33A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVPS33A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDVPS33A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch VPS33A
DgiDB (Drug Gene Interaction Database)VPS33A
DoCM (Curated mutations)VPS33A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VPS33A (select a term)
intoGenVPS33A
Cancer3DVPS33A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610034    617303   
Orphanet
MedgenVPS33A
Genetic Testing Registry VPS33A
NextProtQ96AX1 [Medical]
TSGene65082
GENETestsVPS33A
Target ValidationVPS33A
Huge Navigator VPS33A [HugePedia]
snp3D : Map Gene to Disease65082
BioCentury BCIQVPS33A
ClinGenVPS33A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD65082
Chemical/Pharm GKB GenePA38306
Clinical trialVPS33A
Miscellaneous
canSAR (ICR)VPS33A (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVPS33A
EVEXVPS33A
GoPubMedVPS33A
iHOPVPS33A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 14:11:33 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.