Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome

Donate (in Euros)

Donate (in US Dollars)

VPS35 (vacuolar protein sorting 35 homolog (S. cerevisiae))


Other namesMEM3
HGNC (Hugo) VPS35
LocusID (NCBI) 55737
Location 16q11.2
Location_base_pair Starts at 46693589 and ends at 46723144 bp from pter ( according to hg19-Feb_2009)

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

HGNC (Hugo)VPS35   13487
Entrez_Gene (NCBI)VPS35  55737  vacuolar protein sorting 35 homolog (S. cerevisiae)
GeneCards (Weizmann)VPS35
Ensembl hg19 (Hinxton) [Gene_View]  chr16:46693589-46723144 [Contig_View]  VPS35 [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr16:46693589-46723144 [Contig_View]  VPS35 [Vega]
AceView (NCBI)VPS35
Genatlas (Paris)VPS35
SOURCE (Princeton)VPS35
Genomic and cartography
GoldenPath hg19 (UCSC)VPS35  -     chr16:46693589-46723144 -  16q11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)VPS35  -     16q11.2   [Description]    (hg38-Dec_2013)
EnsemblVPS35 - 16q11.2 [CytoView hg19]  VPS35 - 16q11.2 [CytoView hg38]
Mapping of homologs : NCBIVPS35 [Mapview hg19]  VPS35 [Mapview hg38]
OMIM601501   614203   
Gene and transcription
Genbank (Entrez)AF086051 AF175265 AF183418 AF186382 AF191298
RefSeq transcript (Entrez)NM_018206
RefSeq genomic (Entrez)AC_000148 NC_000016 NC_018927 NG_029970 NT_010498 NW_001838287 NW_004929402
Consensus coding sequences : CCDS (NCBI)VPS35
Cluster EST : UnigeneHs.454528 [ NCBI ]
CGAP (NCI)Hs.454528
Alternative Splicing : Fast-db (Paris)GSHG0011821
Gene ExpressionVPS35 [ NCBI-GEO ]     VPS35 [ SEEK ]   VPS35 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96QK1 (Uniprot)
NextProtQ96QK1  [Medical]
With graphics : InterProQ96QK1
Splice isoforms : SwissVarQ96QK1 (Swissvar)
Domains : Interpro (EBI)ARM-type_fold    Vps35   
Related proteins : CluSTrQ96QK1
Domain families : Pfam (Sanger)Vps35 (PF03635)   
Domain families : Pfam (NCBI)pfam03635   
DMDM Disease mutations55737
Blocks (Seattle)Q96QK1
PDB (SRS)2R17   
PDB (PDBSum)2R17   
PDB (IMB)2R17   
PDB (RSDB)2R17   
Peptide AtlasQ96QK1
IPIIPI00018931   IPI01010570   
Protein Interaction databases
IntAct (EBI)Q96QK1
Ontologies - Pathways
Ontology : AmiGOprotein binding  lysosomal membrane  endosome  cytosol  cytosol  cell death  protein transport  retromer complex  retrograde transport, endosome to Golgi  extracellular vesicular exosome  
Ontology : EGO-EBIprotein binding  lysosomal membrane  endosome  cytosol  cytosol  cell death  protein transport  retromer complex  retrograde transport, endosome to Golgi  extracellular vesicular exosome  
Protein Interaction DatabaseVPS35
DoCM (Curated mutations)VPS35
Wikipedia pathwaysVPS35
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerVPS35 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VPS35
Exome Variant ServerVPS35
SNP (GeneSNP Utah)VPS35
Genetic variants : HAPMAPVPS35
Genomic Variants (DGV)VPS35 [DGVbeta]
Somatic Mutations in Cancer : COSMICVPS35 
CONAN: Copy Number AnalysisVPS35 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
DECIPHER (Syndromes)16:46693589-46723144
Mutations and Diseases : HGMDVPS35
OMIM601501    614203   
NextProtQ96QK1 [Medical]
Disease Genetic AssociationVPS35
Huge Navigator VPS35 [HugePedia]  VPS35 [HugeCancerGEM]
snp3D : Map Gene to Disease55737
DGIdb (Drug Gene Interaction db)VPS35
General knowledge
Homologs : HomoloGeneVPS35
Homology/Alignments : Family Browser (UCSC)VPS35
Phylogenetic Trees/Animal Genes : TreeFamVPS35
Chemical/Protein Interactions : CTD55737
Chemical/Pharm GKB GenePA37783
Clinical trialVPS35
Other databases
PubMed89 Pubmed reference(s) in Entrez
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI


Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 14 19:20:48 CET 2015

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us