VPS37C (VPS37C subunit of ESCRT-I)

2014-11-01  

Identity

HGNC
LOCATION
11q12.2
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 55048
MIM: 610038
HGNC: 26097
Ensembl: ENSG00000167987

Variants:

dbSNP: 55048
ClinVar: 55048
TCGA: ENSG00000167987
COSMIC: VPS37C

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167987ENST00000301765A5D8V6
ENSG00000167987ENST00000538036F5H4Q5

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144
ESCRT-I complexKEGGhsa_M00409
ESCRT-I complexKEGGM00409
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
HIV InfectionREACTOMER-HSA-162906
HIV Life CycleREACTOMER-HSA-162587
Late Phase of HIV Life CycleREACTOMER-HSA-162599
Assembly Of The HIV VirionREACTOMER-HSA-175474
Synthesis And Processing Of GAG, GAGPOL PolyproteinsREACTOMER-HSA-174495
Membrane binding and targetting of GAG proteinsREACTOMER-HSA-174490
Budding and maturation of HIV virionREACTOMER-HSA-162588
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Endosomal Sorting Complex Required For Transport (ESCRT)REACTOMER-HSA-917729

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
155095642005Identification of human VPS37C, a component of endosomal sorting complex required for transport-I important for viral budding.32
239247352013VPS37 isoforms differentially modulate the ternary complex formation of ALIX, ALG-2, and ESCRT-I.7
197732792009Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.6

Citation

Dessen P

VPS37C (VPS37C subunit of ESCRT-I)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75635/vps37c