Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

VSIR (V-set immunoregulatory receptor)

Identity

Alias_namesC10orf54
chromosome 10 open reading frame 54
Alias_symbol (synonym)SISP1
GI24
B7-H5
B7H5
VISTA
PD-1H
Dies1
Other aliasDD1alpha
PP2135
HGNC (Hugo) VSIR
LocusID (NCBI) 64115
Atlas_Id 56664
Location 10q22.1  [Link to chromosome band 10q22]
Location_base_pair Starts at 71747556 and ends at 71773580 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)VSIR   30085
Cards
Entrez_Gene (NCBI)VSIR  64115  V-set immunoregulatory receptor
AliasesB7-H5; B7H5; C10orf54; DD1alpha; 
Dies1; GI24; PD-1H; PP2135; SISP1; VISTA
GeneCards (Weizmann)VSIR
Ensembl hg19 (Hinxton)ENSG00000107738 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000107738 [Gene_View]  ENSG00000107738 [Sequence]  chr10:71747556-71773580 [Contig_View]  VSIR [Vega]
ICGC DataPortalENSG00000107738
TCGA cBioPortalVSIR
AceView (NCBI)VSIR
Genatlas (Paris)VSIR
WikiGenes64115
SOURCE (Princeton)VSIR
Genetics Home Reference (NIH)VSIR
Genomic and cartography
GoldenPath hg38 (UCSC)VSIR  -     chr10:71747556-71773580 -  10q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)VSIR  -     10q22.1   [Description]    (hg19-Feb_2009)
GoldenPathVSIR - 10q22.1 [CytoView hg19]  VSIR - 10q22.1 [CytoView hg38]
ImmunoBaseENSG00000107738
Mapping of homologs : NCBIVSIR [Mapview hg19]  VSIR [Mapview hg38]
OMIM615608   
Gene and transcription
Genbank (Entrez)AB073653 AF193048 AF289594 AK024449 AY265805
RefSeq transcript (Entrez)NM_022153
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)VSIR
Cluster EST : UnigeneHs.47382 [ NCBI ]
CGAP (NCI)Hs.47382
Alternative Splicing GalleryENSG00000107738
Gene ExpressionVSIR [ NCBI-GEO ]   VSIR [ EBI - ARRAY_EXPRESS ]   VSIR [ SEEK ]   VSIR [ MEM ]
Gene Expression Viewer (FireBrowse)VSIR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64115
GTEX Portal (Tissue expression)VSIR
Human Protein AtlasENSG00000107738-VSIR [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H7M9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H7M9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H7M9
Splice isoforms : SwissVarQ9H7M9
PhosPhoSitePlusQ9H7M9
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig_sub    Ig_V-set   
Domain families : Pfam (Sanger)V-set (PF07686)   
Domain families : Pfam (NCBI)pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  
Conserved Domain (NCBI)VSIR
DMDM Disease mutations64115
Blocks (Seattle)VSIR
SuperfamilyQ9H7M9
Human Protein Atlas [tissue]ENSG00000107738-VSIR [tissue]
Peptide AtlasQ9H7M9
IPIIPI00303333   IPI00872022   IPI00103702   
Protein Interaction databases
DIP (DOE-UCLA)Q9H7M9
IntAct (EBI)Q9H7M9
FunCoupENSG00000107738
BioGRIDVSIR
STRING (EMBL)VSIR
ZODIACVSIR
Ontologies - Pathways
QuickGOQ9H7M9
Ontology : AmiGOplasma membrane  positive regulation of gene expression  positive regulation of endopeptidase activity  integral component of membrane  enzyme binding  positive regulation of cell migration  zymogen activation  negative regulation of interferon-gamma production  negative regulation of interleukin-10 production  negative regulation of interleukin-17 production  negative regulation of tumor necrosis factor production  identical protein binding  positive regulation of regulatory T cell differentiation  endopeptidase activator activity  positive regulation of collagen catabolic process  negative regulation of CD4-positive, alpha-beta T cell proliferation  negative regulation of CD8-positive, alpha-beta T cell proliferation  
Ontology : EGO-EBIplasma membrane  positive regulation of gene expression  positive regulation of endopeptidase activity  integral component of membrane  enzyme binding  positive regulation of cell migration  zymogen activation  negative regulation of interferon-gamma production  negative regulation of interleukin-10 production  negative regulation of interleukin-17 production  negative regulation of tumor necrosis factor production  identical protein binding  positive regulation of regulatory T cell differentiation  endopeptidase activator activity  positive regulation of collagen catabolic process  negative regulation of CD4-positive, alpha-beta T cell proliferation  negative regulation of CD8-positive, alpha-beta T cell proliferation  
NDEx NetworkVSIR
Atlas of Cancer Signalling NetworkVSIR
Wikipedia pathwaysVSIR
Orthology - Evolution
OrthoDB64115
GeneTree (enSembl)ENSG00000107738
Phylogenetic Trees/Animal Genes : TreeFamVSIR
HOGENOMQ9H7M9
Homologs : HomoloGeneVSIR
Homology/Alignments : Family Browser (UCSC)VSIR
Gene fusions - Rearrangements
Fusion : QuiverVSIR
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVSIR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VSIR
dbVarVSIR
ClinVarVSIR
1000_GenomesVSIR 
Exome Variant ServerVSIR
ExAC (Exome Aggregation Consortium)ENSG00000107738
GNOMAD BrowserENSG00000107738
Varsome BrowserVSIR
Genetic variants : HAPMAP64115
Genomic Variants (DGV)VSIR [DGVbeta]
DECIPHERVSIR [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisVSIR 
Mutations
ICGC Data PortalVSIR 
TCGA Data PortalVSIR 
Broad Tumor PortalVSIR
OASIS PortalVSIR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVSIR  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DVSIR
Mutations and Diseases : HGMDVSIR
BioMutasearch VSIR
DgiDB (Drug Gene Interaction Database)VSIR
DoCM (Curated mutations)VSIR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VSIR (select a term)
intoGenVSIR
Cancer3DVSIR(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615608   
Orphanet
DisGeNETVSIR
MedgenVSIR
Genetic Testing Registry VSIR
NextProtQ9H7M9 [Medical]
TSGene64115
GENETestsVSIR
Target ValidationVSIR
Huge Navigator VSIR [HugePedia]
snp3D : Map Gene to Disease64115
BioCentury BCIQVSIR
ClinGenVSIR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64115
Chemical/Pharm GKB GenePA142672307
Clinical trialVSIR
Miscellaneous
canSAR (ICR)VSIR (select the gene name)
DataMed IndexVSIR
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVSIR
EVEXVSIR
GoPubMedVSIR
iHOPVSIR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 13 18:15:05 CET 2019
Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.