Atlas of Genetics and Cytogenetics in Oncology and Haematology

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VSNL1 (visinin like 1)

Identity

Alias_symbol (synonym)VILIP
HPCAL3
HUVISL1
HLP3
VILIP-1
Other alias
HGNC (Hugo) VSNL1
LocusID (NCBI) 7447
Atlas_Id 49925
Location 2p24.2  [Link to chromosome band 2p24]
Location_base_pair Starts at 17540540 and ends at 17656439 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BTBD9 (6p21.2) / VSNL1 (2p24.2)PLEKHH2 (2p21) / VSNL1 (2p24.2)THUMPD2 (2p22.1) / VSNL1 (2p24.2)
VSNL1 (2p24.2) / BTBD9 (6p21.2)PLEKHH2 2p21 / VSNL1 2p24.2THUMPD2 2p22.1 / VSNL1 2p24.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(2;2)(p21;p24) PLEKHH2/VSNL1
t(2;2)(p22;p24) THUMPD2/VSNL1

External links

Nomenclature
HGNC (Hugo)VSNL1   12722
Cards
Entrez_Gene (NCBI)VSNL1  7447  visinin like 1
AliasesHLP3; HPCAL3; HUVISL1; VILIP; 
VILIP-1
GeneCards (Weizmann)VSNL1
Ensembl hg19 (Hinxton)ENSG00000163032 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163032 [Gene_View]  ENSG00000163032 [Sequence]  chr2:17540540-17656439 [Contig_View]  VSNL1 [Vega]
ICGC DataPortalENSG00000163032
TCGA cBioPortalVSNL1
AceView (NCBI)VSNL1
Genatlas (Paris)VSNL1
WikiGenes7447
SOURCE (Princeton)VSNL1
Genetics Home Reference (NIH)VSNL1
Genomic and cartography
GoldenPath hg38 (UCSC)VSNL1  -     chr2:17540540-17656439 +  2p24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)VSNL1  -     2p24.2   [Description]    (hg19-Feb_2009)
GoldenPathVSNL1 - 2p24.2 [CytoView hg19]  VSNL1 - 2p24.2 [CytoView hg38]
ImmunoBaseENSG00000163032
Mapping of homologs : NCBIVSNL1 [Mapview hg19]  VSNL1 [Mapview hg38]
OMIM600817   
Gene and transcription
Genbank (Entrez)AB001104 AF039555 AI143139 AK308816 BC022012
RefSeq transcript (Entrez)NM_001366803 NM_001366804 NM_001366805 NM_001366806 NM_003385
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)VSNL1
Cluster EST : UnigeneHs.444212 [ NCBI ]
CGAP (NCI)Hs.444212
Alternative Splicing GalleryENSG00000163032
Gene ExpressionVSNL1 [ NCBI-GEO ]   VSNL1 [ EBI - ARRAY_EXPRESS ]   VSNL1 [ SEEK ]   VSNL1 [ MEM ]
Gene Expression Viewer (FireBrowse)VSNL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7447
GTEX Portal (Tissue expression)VSNL1
Human Protein AtlasENSG00000163032-VSNL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62760   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62760  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62760
Splice isoforms : SwissVarP62760
PhosPhoSitePlusP62760
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom    VILIP-1   
Domain families : Pfam (Sanger)EF-hand_1 (PF00036)    EF-hand_7 (PF13499)   
Domain families : Pfam (NCBI)pfam00036    pfam13499   
Domain families : Smart (EMBL)EFh (SM00054)  
Conserved Domain (NCBI)VSNL1
DMDM Disease mutations7447
Blocks (Seattle)VSNL1
SuperfamilyP62760
Human Protein Atlas [tissue]ENSG00000163032-VSNL1 [tissue]
Peptide AtlasP62760
HPRD02890
IPIIPI00216313   IPI00894012   IPI00893091   
Protein Interaction databases
DIP (DOE-UCLA)P62760
IntAct (EBI)P62760
FunCoupENSG00000163032
BioGRIDVSNL1
STRING (EMBL)VSNL1
ZODIACVSNL1
Ontologies - Pathways
QuickGOP62760
Ontology : AmiGOcalcium ion binding  protein binding  cytosol  membrane  positive regulation of insulin secretion involved in cellular response to glucose stimulus  positive regulation of exocytosis  negative regulation of insulin secretion  
Ontology : EGO-EBIcalcium ion binding  protein binding  cytosol  membrane  positive regulation of insulin secretion involved in cellular response to glucose stimulus  positive regulation of exocytosis  negative regulation of insulin secretion  
NDEx NetworkVSNL1
Atlas of Cancer Signalling NetworkVSNL1
Wikipedia pathwaysVSNL1
Orthology - Evolution
OrthoDB7447
GeneTree (enSembl)ENSG00000163032
Phylogenetic Trees/Animal Genes : TreeFamVSNL1
HOGENOMP62760
Homologs : HomoloGeneVSNL1
Homology/Alignments : Family Browser (UCSC)VSNL1
Gene fusions - Rearrangements
Fusion : MitelmanPLEKHH2/VSNL1 [2p21/2p24.2]  [t(2;2)(p21;p24)]  
Fusion : MitelmanTHUMPD2/VSNL1 [2p22.1/2p24.2]  [t(2;2)(p22;p24)]  
Fusion PortalPLEKHH2 2p21 VSNL1 2p24.2 PRAD
Fusion PortalTHUMPD2 2p22.1 VSNL1 2p24.2 LUAD
Fusion : QuiverVSNL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVSNL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VSNL1
dbVarVSNL1
ClinVarVSNL1
1000_GenomesVSNL1 
Exome Variant ServerVSNL1
ExAC (Exome Aggregation Consortium)ENSG00000163032
GNOMAD BrowserENSG00000163032
Varsome BrowserVSNL1
Genetic variants : HAPMAP7447
Genomic Variants (DGV)VSNL1 [DGVbeta]
DECIPHERVSNL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisVSNL1 
Mutations
ICGC Data PortalVSNL1 
TCGA Data PortalVSNL1 
Broad Tumor PortalVSNL1
OASIS PortalVSNL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVSNL1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DVSNL1
Mutations and Diseases : HGMDVSNL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch VSNL1
DgiDB (Drug Gene Interaction Database)VSNL1
DoCM (Curated mutations)VSNL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VSNL1 (select a term)
intoGenVSNL1
Cancer3DVSNL1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600817   
Orphanet
DisGeNETVSNL1
MedgenVSNL1
Genetic Testing Registry VSNL1
NextProtP62760 [Medical]
TSGene7447
GENETestsVSNL1
Target ValidationVSNL1
Huge Navigator VSNL1 [HugePedia]
snp3D : Map Gene to Disease7447
BioCentury BCIQVSNL1
ClinGenVSNL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7447
Chemical/Pharm GKB GenePA37333
Clinical trialVSNL1
Miscellaneous
canSAR (ICR)VSNL1 (select the gene name)
DataMed IndexVSNL1
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVSNL1
EVEXVSNL1
GoPubMedVSNL1
iHOPVSNL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 13 18:15:05 CET 2019
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