Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

VWC2 (von Willebrand factor C domain containing 2)

Identity

Alias_symbol (synonym)PSST739
UNQ739
Other alias
HGNC (Hugo) VWC2
LocusID (NCBI) 375567
Atlas_Id 75670
Location 7p12.2  [Link to chromosome band 7p12]
Location_base_pair Starts at 49813257 and ends at 49952138 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CASD1 (7q21.3) / VWC2 (7p12.2)MAGI2 (7q21.11) / VWC2 (7p12.2)PTPRR (12q15) / VWC2 (7p12.2)
VWC2 (7p12.2) / RAB20 (13q34)CASD1 VWC2PTPRR VWC2
MAGI2 VWC2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)VWC2   30200
Cards
Entrez_Gene (NCBI)VWC2  375567  von Willebrand factor C domain containing 2
AliasesPSST739; UNQ739
GeneCards (Weizmann)VWC2
Ensembl hg19 (Hinxton) [Gene_View]  chr7:49813257-49952138 [Contig_View]  VWC2 [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr7:49813257-49952138 [Contig_View]  VWC2 [Vega]
TCGA cBioPortalVWC2
AceView (NCBI)VWC2
Genatlas (Paris)VWC2
WikiGenes375567
SOURCE (Princeton)VWC2
Genetics Home Reference (NIH)VWC2
Genomic and cartography
GoldenPath hg19 (UCSC)VWC2  -     chr7:49813257-49952138 +  7p12.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)VWC2  -     7p12.2   [Description]    (hg38-Dec_2013)
EnsemblVWC2 - 7p12.2 [CytoView hg19]  VWC2 - 7p12.2 [CytoView hg38]
Mapping of homologs : NCBIVWC2 [Mapview hg19]  VWC2 [Mapview hg38]
OMIM611108   
Gene and transcription
Genbank (Entrez)AB292671 AY358393 BC110857
RefSeq transcript (Entrez)NM_198570
RefSeq genomic (Entrez)NC_000007 NC_018918 NT_007819 NW_004929329
Consensus coding sequences : CCDS (NCBI)VWC2
Cluster EST : UnigeneHs.629302 [ NCBI ]
CGAP (NCI)Hs.629302
Gene ExpressionVWC2 [ NCBI-GEO ]   VWC2 [ EBI - ARRAY_EXPRESS ]   VWC2 [ SEEK ]   VWC2 [ MEM ]
Gene Expression Viewer (FireBrowse)VWC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)375567
GTEX Portal (Tissue expression)VWC2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ2TAL6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ2TAL6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ2TAL6
Splice isoforms : SwissVarQ2TAL6
PhosPhoSitePlusQ2TAL6
Domaine pattern : Prosite (Expaxy)VWFC_1 (PS01208)    VWFC_2 (PS50184)   
Domains : Interpro (EBI)Brorin    VWF_C   
Domain families : Pfam (Sanger)VWC (PF00093)   
Domain families : Pfam (NCBI)pfam00093   
Domain families : Smart (EMBL)VWC (SM00214)  
Conserved Domain (NCBI)VWC2
DMDM Disease mutations375567
Blocks (Seattle)VWC2
SuperfamilyQ2TAL6
Peptide AtlasQ2TAL6
HPRD18271
IPIIPI00394870   
Protein Interaction databases
DIP (DOE-UCLA)Q2TAL6
IntAct (EBI)Q2TAL6
BioGRIDVWC2
STRING (EMBL)VWC2
ZODIACVWC2
Ontologies - Pathways
QuickGOQ2TAL6
Ontology : AmiGOmolecular_function  basement membrane  interstitial matrix  extracellular space  positive regulation of cell-substrate adhesion  cell junction  negative regulation of BMP signaling pathway  alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex  synapse  positive regulation of neuron differentiation  
Ontology : EGO-EBImolecular_function  basement membrane  interstitial matrix  extracellular space  positive regulation of cell-substrate adhesion  cell junction  negative regulation of BMP signaling pathway  alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex  synapse  positive regulation of neuron differentiation  
NDEx NetworkVWC2
Atlas of Cancer Signalling NetworkVWC2
Wikipedia pathwaysVWC2
Orthology - Evolution
OrthoDB375567
Phylogenetic Trees/Animal Genes : TreeFamVWC2
HOVERGENQ2TAL6
HOGENOMQ2TAL6
Homologs : HomoloGeneVWC2
Homology/Alignments : Family Browser (UCSC)VWC2
Gene fusions - Rearrangements
Fusion: TCGACASD1 VWC2
Fusion: TCGAPTPRR VWC2
Fusion: TCGAMAGI2 VWC2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVWC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VWC2
dbVarVWC2
ClinVarVWC2
1000_GenomesVWC2 
Exome Variant ServerVWC2
ExAC (Exome Aggregation Consortium)VWC2 (select the gene name)
Genetic variants : HAPMAP375567
Genomic Variants (DGV)VWC2 [DGVbeta]
DECIPHER (Syndromes)7:49813257-49952138  
CONAN: Copy Number AnalysisVWC2 
Mutations
ICGC Data PortalVWC2 
TCGA Data PortalVWC2 
Broad Tumor PortalVWC2
OASIS PortalVWC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVWC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDVWC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch VWC2
DgiDB (Drug Gene Interaction Database)VWC2
DoCM (Curated mutations)VWC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VWC2 (select a term)
intoGenVWC2
Cancer3DVWC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611108   
Orphanet
MedgenVWC2
Genetic Testing Registry VWC2
NextProtQ2TAL6 [Medical]
TSGene375567
GENETestsVWC2
Huge Navigator VWC2 [HugePedia]
snp3D : Map Gene to Disease375567
BioCentury BCIQVWC2
ClinGenVWC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD375567
Chemical/Pharm GKB GenePA147357154
Clinical trialVWC2
Miscellaneous
canSAR (ICR)VWC2 (select the gene name)
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVWC2
EVEXVWC2
GoPubMedVWC2
iHOPVWC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:51:26 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.