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VWC2L (von Willebrand factor C domain containing protein 2-like)

Identity

Alias_namesvon Willebrand factor C domain-containing protein 2-like
Other alias-
HGNC (Hugo) VWC2L
LocusID (NCBI) 402117
Atlas_Id 75671
Location 2q34  [Link to chromosome band 2q34]
Location_base_pair Starts at 215276461 and ends at 215440653 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PARD3B (2q33.3) / VWC2L (2q34)PGAP1 (2q33.1) / VWC2L (2q34)PGAP1 VWC2L
PARD3B VWC2L

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)VWC2L   37203
Cards
Entrez_Gene (NCBI)VWC2L  402117  von Willebrand factor C domain containing protein 2-like
Aliases
GeneCards (Weizmann)VWC2L
Ensembl hg19 (Hinxton)ENSG00000174453 [Gene_View]  chr2:215276461-215440653 [Contig_View]  VWC2L [Vega]
Ensembl hg38 (Hinxton)ENSG00000174453 [Gene_View]  chr2:215276461-215440653 [Contig_View]  VWC2L [Vega]
ICGC DataPortalENSG00000174453
TCGA cBioPortalVWC2L
AceView (NCBI)VWC2L
Genatlas (Paris)VWC2L
WikiGenes402117
SOURCE (Princeton)VWC2L
Genetics Home Reference (NIH)VWC2L
Genomic and cartography
GoldenPath hg19 (UCSC)VWC2L  -     chr2:215276461-215440653 +  2q34   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)VWC2L  -     2q34   [Description]    (hg38-Dec_2013)
EnsemblVWC2L - 2q34 [CytoView hg19]  VWC2L - 2q34 [CytoView hg38]
Mapping of homologs : NCBIVWC2L [Mapview hg19]  VWC2L [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB374231 BC146903 BC146911 BC146931 BC146935
RefSeq transcript (Entrez)NM_001080500
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005403 NW_004929305
Consensus coding sequences : CCDS (NCBI)VWC2L
Cluster EST : UnigeneHs.534834 [ NCBI ]
CGAP (NCI)Hs.534834
Alternative Splicing GalleryENSG00000174453
Gene ExpressionVWC2L [ NCBI-GEO ]   VWC2L [ EBI - ARRAY_EXPRESS ]   VWC2L [ SEEK ]   VWC2L [ MEM ]
Gene Expression Viewer (FireBrowse)VWC2L [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)402117
GTEX Portal (Tissue expression)VWC2L
Protein : pattern, domain, 3D structure
UniProt/SwissProtB2RUY7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtB2RUY7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProB2RUY7
Splice isoforms : SwissVarB2RUY7
PhosPhoSitePlusB2RUY7
Domaine pattern : Prosite (Expaxy)VWFC_1 (PS01208)    VWFC_2 (PS50184)   
Domains : Interpro (EBI)VWF_C   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)VWC (SM00214)  
Conserved Domain (NCBI)VWC2L
DMDM Disease mutations402117
Blocks (Seattle)VWC2L
SuperfamilyB2RUY7
Human Protein AtlasENSG00000174453
Peptide AtlasB2RUY7
IPIIPI00402291   IPI00941625   IPI00902962   
Protein Interaction databases
DIP (DOE-UCLA)B2RUY7
IntAct (EBI)B2RUY7
FunCoupENSG00000174453
BioGRIDVWC2L
STRING (EMBL)VWC2L
ZODIACVWC2L
Ontologies - Pathways
QuickGOB2RUY7
Ontology : AmiGOextracellular space  cell junction  negative regulation of BMP signaling pathway  alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex  synapse  positive regulation of neuron differentiation  
Ontology : EGO-EBIextracellular space  cell junction  negative regulation of BMP signaling pathway  alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex  synapse  positive regulation of neuron differentiation  
NDEx NetworkVWC2L
Atlas of Cancer Signalling NetworkVWC2L
Wikipedia pathwaysVWC2L
Orthology - Evolution
OrthoDB402117
GeneTree (enSembl)ENSG00000174453
Phylogenetic Trees/Animal Genes : TreeFamVWC2L
HOVERGENB2RUY7
HOGENOMB2RUY7
Homologs : HomoloGeneVWC2L
Homology/Alignments : Family Browser (UCSC)VWC2L
Gene fusions - Rearrangements
Fusion: TCGAPGAP1 VWC2L
Fusion: TCGAPARD3B VWC2L
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerVWC2L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)VWC2L
dbVarVWC2L
ClinVarVWC2L
1000_GenomesVWC2L 
Exome Variant ServerVWC2L
ExAC (Exome Aggregation Consortium)VWC2L (select the gene name)
Genetic variants : HAPMAP402117
Genomic Variants (DGV)VWC2L [DGVbeta]
DECIPHER (Syndromes)2:215276461-215440653  ENSG00000174453
CONAN: Copy Number AnalysisVWC2L 
Mutations
ICGC Data PortalVWC2L 
TCGA Data PortalVWC2L 
Broad Tumor PortalVWC2L
OASIS PortalVWC2L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICVWC2L  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDVWC2L
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch VWC2L
DgiDB (Drug Gene Interaction Database)VWC2L
DoCM (Curated mutations)VWC2L (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)VWC2L (select a term)
intoGenVWC2L
Cancer3DVWC2L(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenVWC2L
Genetic Testing Registry VWC2L
NextProtB2RUY7 [Medical]
TSGene402117
GENETestsVWC2L
Huge Navigator VWC2L [HugePedia]
snp3D : Map Gene to Disease402117
BioCentury BCIQVWC2L
ClinGenVWC2L
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD402117
Chemical/Pharm GKB GenePA165697841
Clinical trialVWC2L
Miscellaneous
canSAR (ICR)VWC2L (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineVWC2L
EVEXVWC2L
GoPubMedVWC2L
iHOPVWC2L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:51:26 CET 2017

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