Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

WASHC1 (WASH complex subunit 1)

Identity

Other aliasFAM39E
WASH
WASH1
HGNC (Hugo) WASHC1
LocusID (NCBI) 100287171
Atlas_Id 56793
Location 9p24.3  [Link to chromosome band 9p24]
Location_base_pair Starts at 14511 and ends at 29739 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WASHC1   24361
Cards
Entrez_Gene (NCBI)WASHC1  100287171  WASH complex subunit 1
AliasesFAM39E; WASH; WASH1
GeneCards (Weizmann)WASHC1
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr9:14511-29739 [Contig_View]  WASHC1 [Vega]
TCGA cBioPortalWASHC1
AceView (NCBI)WASHC1
Genatlas (Paris)WASHC1
WikiGenes100287171
SOURCE (Princeton)WASHC1
Genetics Home Reference (NIH)WASHC1
Genomic and cartography
GoldenPath hg38 (UCSC)WASHC1  -     chr9:14511-29739 -  9p24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WASHC1  -     9p24.3   [Description]    (hg19-Feb_2009)
EnsemblWASHC1 - 9p24.3 [CytoView hg19]  WASHC1 - 9p24.3 [CytoView hg38]
Mapping of homologs : NCBIWASHC1 [Mapview hg19]  WASHC1 [Mapview hg38]
OMIM613632   
Gene and transcription
Genbank (Entrez)AK024448 AK024481 AK289708 AK309568 BC014406
RefSeq transcript (Entrez)NM_182905
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)WASHC1
Cluster EST : UnigeneHs.709408 [ NCBI ]
CGAP (NCI)Hs.709408
Gene ExpressionWASHC1 [ NCBI-GEO ]   WASHC1 [ EBI - ARRAY_EXPRESS ]   WASHC1 [ SEEK ]   WASHC1 [ MEM ]
Gene Expression Viewer (FireBrowse)WASHC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)100287171
GTEX Portal (Tissue expression)WASHC1
Protein : pattern, domain, 3D structure
UniProt/SwissProtA8K0Z3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA8K0Z3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA8K0Z3
Splice isoforms : SwissVarA8K0Z3
PhosPhoSitePlusA8K0Z3
Domains : Interpro (EBI)WASH1    WASH1_WAHD   
Domain families : Pfam (Sanger)WASH_WAHD (PF11945)   
Domain families : Pfam (NCBI)pfam11945   
Conserved Domain (NCBI)WASHC1
DMDM Disease mutations100287171
Blocks (Seattle)WASHC1
SuperfamilyA8K0Z3
Peptide AtlasA8K0Z3
IPIIPI00954866   IPI01012444   IPI00017695   
Protein Interaction databases
DIP (DOE-UCLA)A8K0Z3
IntAct (EBI)A8K0Z3
BioGRIDWASHC1
STRING (EMBL)WASHC1
ZODIACWASHC1
Ontologies - Pathways
QuickGOA8K0Z3
Ontology : AmiGOexocyst  oocyte maturation  dendritic cell antigen processing and presentation  actin binding  protein binding  early endosome  early endosome  late endosome  autophagosome  centrosome  centriole  exocytosis  endosome organization  negative regulation of autophagy  endosomal transport  extracellular matrix disassembly  positive regulation of cell migration  BLOC-1 complex  positive regulation of pseudopodium assembly  regulation of protein ubiquitination  ubiquitin protein ligase binding  early endosome membrane  Arp2/3 complex-mediated actin nucleation  Arp2/3 complex-mediated actin nucleation  low-density lipoprotein particle clearance  protein localization to cell surface  polar body extrusion after meiotic divisions  T cell proliferation  retrograde transport, endosome to Golgi  retrograde transport, endosome to Golgi  alpha-tubulin binding  gamma-tubulin binding  intracellular membrane-bounded organelle  negative regulation of phosphatidylinositol 3-kinase activity  regulation of immune response  recycling endosome  recycling endosome membrane  WASH complex  invadopodium  spindle assembly involved in meiosis  endosome to plasma membrane protein transport  positive regulation of cholesterol import  retrograde transport, endosome to plasma membrane  positive regulation of protein localization to cell surface  
Ontology : EGO-EBIexocyst  oocyte maturation  dendritic cell antigen processing and presentation  actin binding  protein binding  early endosome  early endosome  late endosome  autophagosome  centrosome  centriole  exocytosis  endosome organization  negative regulation of autophagy  endosomal transport  extracellular matrix disassembly  positive regulation of cell migration  BLOC-1 complex  positive regulation of pseudopodium assembly  regulation of protein ubiquitination  ubiquitin protein ligase binding  early endosome membrane  Arp2/3 complex-mediated actin nucleation  Arp2/3 complex-mediated actin nucleation  low-density lipoprotein particle clearance  protein localization to cell surface  polar body extrusion after meiotic divisions  T cell proliferation  retrograde transport, endosome to Golgi  retrograde transport, endosome to Golgi  alpha-tubulin binding  gamma-tubulin binding  intracellular membrane-bounded organelle  negative regulation of phosphatidylinositol 3-kinase activity  regulation of immune response  recycling endosome  recycling endosome membrane  WASH complex  invadopodium  spindle assembly involved in meiosis  endosome to plasma membrane protein transport  positive regulation of cholesterol import  retrograde transport, endosome to plasma membrane  positive regulation of protein localization to cell surface  
NDEx NetworkWASHC1
Atlas of Cancer Signalling NetworkWASHC1
Wikipedia pathwaysWASHC1
Orthology - Evolution
OrthoDB100287171
Phylogenetic Trees/Animal Genes : TreeFamWASHC1
HOVERGENA8K0Z3
HOGENOMA8K0Z3
Homologs : HomoloGeneWASHC1
Homology/Alignments : Family Browser (UCSC)WASHC1
Gene fusions - Rearrangements
Tumor Fusion PortalWASHC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWASHC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WASHC1
dbVarWASHC1
ClinVarWASHC1
1000_GenomesWASHC1 
Exome Variant ServerWASHC1
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP100287171
Genomic Variants (DGV)WASHC1 [DGVbeta]
DECIPHERWASHC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWASHC1 
Mutations
ICGC Data PortalWASHC1 
TCGA Data PortalWASHC1 
Broad Tumor PortalWASHC1
OASIS PortalWASHC1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDWASHC1
BioMutasearch WASHC1
DgiDB (Drug Gene Interaction Database)WASHC1
DoCM (Curated mutations)WASHC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WASHC1 (select a term)
intoGenWASHC1
Cancer3DWASHC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613632   
Orphanet
DisGeNETWASHC1
MedgenWASHC1
Genetic Testing Registry WASHC1
NextProtA8K0Z3 [Medical]
TSGene100287171
GENETestsWASHC1
Target ValidationWASHC1
Huge Navigator WASHC1 [HugePedia]
snp3D : Map Gene to Disease100287171
BioCentury BCIQWASHC1
ClinGenWASHC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD100287171
Chemical/Pharm GKB GenePA162409121
Clinical trialWASHC1
Miscellaneous
canSAR (ICR)WASHC1 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWASHC1
EVEXWASHC1
GoPubMedWASHC1
iHOPWASHC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:41:31 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.