Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

WASHC2C (WASH complex subunit 2C)

Identity

Alias (NCBI)FAM21A
FAM21C
VPEF
HGNC (Hugo) WASHC2C
LocusID (NCBI) 253725
Atlas_Id 78794
Location 10q11.22  [Link to chromosome band 10q11]
Location_base_pair Starts at 45727266 and ends at 45792964 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

 

Nomenclature
HGNC (Hugo)WASHC2C   23414
Cards
Entrez_Gene (NCBI)WASHC2C    WASH complex subunit 2C
AliasesFAM21A; FAM21C; VPEF
GeneCards (Weizmann)WASHC2C
Ensembl hg19 (Hinxton)ENSG00000172661 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172661 [Gene_View]  ENSG00000172661 [Sequence]  chr10:45727266-45792964 [Contig_View]  WASHC2C [Vega]
ICGC DataPortalENSG00000172661
TCGA cBioPortalWASHC2C
AceView (NCBI)WASHC2C
Genatlas (Paris)WASHC2C
SOURCE (Princeton)WASHC2C
Genetics Home Reference (NIH)WASHC2C
Genomic and cartography
GoldenPath hg38 (UCSC)WASHC2C  -     chr10:45727266-45792964 +  10q11.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WASHC2C  -     10q11.22   [Description]    (hg19-Feb_2009)
GoldenPathWASHC2C - 10q11.22 [CytoView hg19]  WASHC2C - 10q11.22 [CytoView hg38]
ImmunoBaseENSG00000172661
Genome Data Viewer NCBIWASHC2C [Mapview hg19]  
OMIM613631   
Gene and transcription
Genbank (Entrez)AB011164 AI023041 AI356516 AK001545 AK291430
RefSeq transcript (Entrez)NM_001169106 NM_001169107 NM_001330074 NM_001367393 NM_001367394 NM_001367395 NM_001367396 NM_001367397 NM_001367398 NM_001367399 NM_001367400 NM_001367401 NM_001367402 NM_001367403 NM_001367404 NM_001367405 NM_001367406 NM_001367407 NM_001367408 NM_001367409 NM_001367410 NM_001367411 NM_001367412 NM_001367413 NM_001367414 NM_001367415 NM_001367416 NM_015262
Consensus coding sequences : CCDS (NCBI)WASHC2C
Gene ExpressionWASHC2C [ NCBI-GEO ]   WASHC2C [ EBI - ARRAY_EXPRESS ]   WASHC2C [ SEEK ]   WASHC2C [ MEM ]
Gene Expression Viewer (FireBrowse)WASHC2C [ Firebrowse - Broad ]
GenevisibleExpression of WASHC2C in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)253725
GTEX Portal (Tissue expression)WASHC2C
Human Protein AtlasENSG00000172661-WASHC2C [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y4E1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y4E1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y4E1
PhosPhoSitePlusQ9Y4E1
Domains : Interpro (EBI)FAM21/CAPZIP   
Domain families : Pfam (Sanger)CAP-ZIP_m (PF15255)   
Domain families : Pfam (NCBI)pfam15255   
Conserved Domain (NCBI)WASHC2C
SuperfamilyQ9Y4E1
AlphaFold pdb e-kbQ9Y4E1   
Human Protein Atlas [tissue]ENSG00000172661-WASHC2C [tissue]
HPRD11094
Protein Interaction databases
DIP (DOE-UCLA)Q9Y4E1
IntAct (EBI)Q9Y4E1
BioGRIDWASHC2C
STRING (EMBL)WASHC2C
ZODIACWASHC2C
Ontologies - Pathways
QuickGOQ9Y4E1
Ontology : AmiGOprotein binding  phosphatidylinositol-4,5-bisphosphate binding  phosphatidylinositol-3,4,5-trisphosphate binding  nucleolus  endosome  early endosome  cytosol  plasma membrane  phosphatidylinositol-5-phosphate binding  protein transport  early endosome membrane  phosphatidylinositol-3-phosphate binding  endocytic recycling  protein localization to endosome  retrograde transport, endosome to Golgi  intracellular membrane-bounded organelle  phosphatidylinositol-3,4-bisphosphate binding  phosphatidylinositol-4-phosphate binding  WASH complex  phosphatidylinositol-3,5-bisphosphate binding  regulation of substrate adhesion-dependent cell spreading  retromer complex binding  retromer complex binding  negative regulation of barbed-end actin filament capping  
Ontology : EGO-EBIprotein binding  phosphatidylinositol-4,5-bisphosphate binding  phosphatidylinositol-3,4,5-trisphosphate binding  nucleolus  endosome  early endosome  cytosol  plasma membrane  phosphatidylinositol-5-phosphate binding  protein transport  early endosome membrane  phosphatidylinositol-3-phosphate binding  endocytic recycling  protein localization to endosome  retrograde transport, endosome to Golgi  intracellular membrane-bounded organelle  phosphatidylinositol-3,4-bisphosphate binding  phosphatidylinositol-4-phosphate binding  WASH complex  phosphatidylinositol-3,5-bisphosphate binding  regulation of substrate adhesion-dependent cell spreading  retromer complex binding  retromer complex binding  negative regulation of barbed-end actin filament capping  
NDEx NetworkWASHC2C
Atlas of Cancer Signalling NetworkWASHC2C
Wikipedia pathwaysWASHC2C
Orthology - Evolution
OrthoDB253725
GeneTree (enSembl)ENSG00000172661
Phylogenetic Trees/Animal Genes : TreeFamWASHC2C
Homologs : HomoloGeneWASHC2C
Homology/Alignments : Family Browser (UCSC)WASHC2C
Gene fusions - Rearrangements
Fusion : QuiverWASHC2C
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWASHC2C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WASHC2C
dbVarWASHC2C
ClinVarWASHC2C
MonarchWASHC2C
1000_GenomesWASHC2C 
Exome Variant ServerWASHC2C
GNOMAD BrowserENSG00000172661
Varsome BrowserWASHC2C
ACMGWASHC2C variants
VarityQ9Y4E1
Genomic Variants (DGV)WASHC2C [DGVbeta]
DECIPHERWASHC2C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWASHC2C 
Mutations
ICGC Data PortalWASHC2C 
TCGA Data PortalWASHC2C 
Broad Tumor PortalWASHC2C
OASIS PortalWASHC2C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWASHC2C  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DWASHC2C
Mutations and Diseases : HGMDWASHC2C
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaWASHC2C
DgiDB (Drug Gene Interaction Database)WASHC2C
DoCM (Curated mutations)WASHC2C
CIViC (Clinical Interpretations of Variants in Cancer)WASHC2C
Cancer3DWASHC2C
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613631   
Orphanet
DisGeNETWASHC2C
MedgenWASHC2C
Genetic Testing Registry WASHC2C
NextProtQ9Y4E1 [Medical]
GENETestsWASHC2C
Target ValidationWASHC2C
Huge Navigator WASHC2C [HugePedia]
ClinGenWASHC2C
Clinical trials, drugs, therapy
MyCancerGenomeWASHC2C
Protein Interactions : CTDWASHC2C
Pharm GKB GenePA128394768
PharosQ9Y4E1
Clinical trialWASHC2C
Miscellaneous
canSAR (ICR)WASHC2C
HarmonizomeWASHC2C
DataMed IndexWASHC2C
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXWASHC2C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 16:28:22 CEST 2021
Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.