WBP11 (WW domain binding protein 11)

2014-11-01  

Identity

HGNC
LOCATION
12p12.3
LOCUSID
ALIAS
BUG13,CFAP90,FAP90,NPWBP,PPP1R165,SIPP1,VCTERL,VCTRL,WBP-11
FUSION GENES

Other Information

Locus ID:

NCBI: 51729
MIM: 618083
HGNC: 16461
Ensembl: ENSG00000084463

Variants:

dbSNP: 51729
ClinVar: 51729
TCGA: ENSG00000084463
COSMIC: WBP11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000084463ENST00000261167Q9Y2W2
ENSG00000084463ENST00000261167A0A024RAW9
ENSG00000084463ENST00000535328F5GXS9
ENSG00000084463ENST00000535638F5H5G4

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040
Spliceosome, Prp19/CDC5L complexKEGGhsa_M00353
Spliceosome, Prp19/CDC5L complexKEGGM00353
Gene ExpressionREACTOMER-HSA-74160
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
161624982005Nucleocytoplasmic shuttling of the splicing factor SIPP1.14
274565462016Changes in the folding landscape of the WW domain provide a molecular mechanism for an inherited genetic syndrome.3

Citation

Dessen P

WBP11 (WW domain binding protein 11)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75683/wbp11