Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

WBP4 (WW domain binding protein 4)

Identity

Alias (NCBI)FBP21
HGNC (Hugo) WBP4
HGNC Alias symbFBP21
MGC117310
HGNC Alias nameformin binding protein 21
LocusID (NCBI) 11193
Atlas_Id 75688
Location 13q14.11  [Link to chromosome band 13q14]
Location_base_pair Starts at 41061509 and ends at 41084006 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
WBP4 (13q14.11) / FANK1 (10q26.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)WBP4   12739
Cards
Entrez_Gene (NCBI)WBP4    WW domain binding protein 4
AliasesFBP21
GeneCards (Weizmann)WBP4
Ensembl hg19 (Hinxton)ENSG00000120688 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000120688 [Gene_View]  ENSG00000120688 [Sequence]  chr13:41061509-41084006 [Contig_View]  WBP4 [Vega]
ICGC DataPortalENSG00000120688
TCGA cBioPortalWBP4
AceView (NCBI)WBP4
Genatlas (Paris)WBP4
SOURCE (Princeton)WBP4
Genetics Home Reference (NIH)WBP4
Genomic and cartography
GoldenPath hg38 (UCSC)WBP4  -     chr13:41061509-41084006 +  13q14.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WBP4  -     13q14.11   [Description]    (hg19-Feb_2009)
GoldenPathWBP4 - 13q14.11 [CytoView hg19]  WBP4 - 13q14.11 [CytoView hg38]
ImmunoBaseENSG00000120688
genome Data Viewer NCBIWBP4 [Mapview hg19]  
OMIM604981   
Gene and transcription
Genbank (Entrez)AF071185 AK000979 AK001557 AK297536 AK314525
RefSeq transcript (Entrez)NM_007187
Consensus coding sequences : CCDS (NCBI)WBP4
Alternative Splicing GalleryENSG00000120688
Gene ExpressionWBP4 [ NCBI-GEO ]   WBP4 [ EBI - ARRAY_EXPRESS ]   WBP4 [ SEEK ]   WBP4 [ MEM ]
Gene Expression Viewer (FireBrowse)WBP4 [ Firebrowse - Broad ]
GenevisibleExpression of WBP4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11193
GTEX Portal (Tissue expression)WBP4
Human Protein AtlasENSG00000120688-WBP4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75554   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75554  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75554
PhosPhoSitePlusO75554
Domaine pattern : Prosite (Expaxy)WW_DOMAIN_1 (PS01159)    WW_DOMAIN_2 (PS50020)    ZF_MATRIN (PS50171)   
Domains : Interpro (EBI)Matrin/U1-C_Znf_C2H2    Matrin/U1-like-C_Znf_C2H2    U1-CZ_Znf_C2H2    WBP4    WW_dom    WW_dom_sf    Znf_C2H2_sf   
Domain families : Pfam (Sanger)WW (PF00397)    zf-U1 (PF06220)   
Domain families : Pfam (NCBI)pfam00397    pfam06220   
Domain families : Smart (EMBL)WW (SM00456)  ZnF_U1 (SM00451)  
Conserved Domain (NCBI)WBP4
PDB (RSDB)2DK1    2JXW    5O9Z    6AHD   
PDB Europe2DK1    2JXW    5O9Z    6AHD   
PDB (PDBSum)2DK1    2JXW    5O9Z    6AHD   
PDB (IMB)2DK1    2JXW    5O9Z    6AHD   
Structural Biology KnowledgeBase2DK1    2JXW    5O9Z    6AHD   
SCOP (Structural Classification of Proteins)2DK1    2JXW    5O9Z    6AHD   
CATH (Classification of proteins structures)2DK1    2JXW    5O9Z    6AHD   
SuperfamilyO75554
AlphaFold pdb e-kbO75554   
Human Protein Atlas [tissue]ENSG00000120688-WBP4 [tissue]
HPRD16086
Protein Interaction databases
DIP (DOE-UCLA)O75554
IntAct (EBI)O75554
BioGRIDWBP4
STRING (EMBL)WBP4
ZODIACWBP4
Ontologies - Pathways
QuickGOO75554
Ontology : AmiGOmRNA splicing, via spliceosome  mRNA splicing, via spliceosome  RNA binding  protein binding  nucleus  nucleoplasm  zinc ion binding  RNA splicing  nuclear speck  mRNA cis splicing, via spliceosome  proline-rich region binding  U2-type precatalytic spliceosome  precatalytic spliceosome  
Ontology : EGO-EBImRNA splicing, via spliceosome  mRNA splicing, via spliceosome  RNA binding  protein binding  nucleus  nucleoplasm  zinc ion binding  RNA splicing  nuclear speck  mRNA cis splicing, via spliceosome  proline-rich region binding  U2-type precatalytic spliceosome  precatalytic spliceosome  
NDEx NetworkWBP4
Atlas of Cancer Signalling NetworkWBP4
Wikipedia pathwaysWBP4
Orthology - Evolution
OrthoDB11193
GeneTree (enSembl)ENSG00000120688
Phylogenetic Trees/Animal Genes : TreeFamWBP4
Homologs : HomoloGeneWBP4
Homology/Alignments : Family Browser (UCSC)WBP4
Gene fusions - Rearrangements
Fusion : QuiverWBP4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWBP4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WBP4
dbVarWBP4
ClinVarWBP4
MonarchWBP4
1000_GenomesWBP4 
Exome Variant ServerWBP4
GNOMAD BrowserENSG00000120688
Varsome BrowserWBP4
Genomic Variants (DGV)WBP4 [DGVbeta]
DECIPHERWBP4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWBP4 
Mutations
ICGC Data PortalWBP4 
TCGA Data PortalWBP4 
Broad Tumor PortalWBP4
OASIS PortalWBP4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWBP4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DWBP4
Mutations and Diseases : HGMDWBP4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutasearch WBP4
DgiDB (Drug Gene Interaction Database)WBP4
DoCM (Curated mutations)WBP4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WBP4 (select a term)
Cancer3DWBP4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604981   
Orphanet
DisGeNETWBP4
MedgenWBP4
Genetic Testing Registry WBP4
NextProtO75554 [Medical]
GENETestsWBP4
Target ValidationWBP4
Huge Navigator WBP4 [HugePedia]
ClinGenWBP4
Clinical trials, drugs, therapy
MyCancerGenomeWBP4
Protein Interactions : CTDWBP4
Pharm GKB GenePA37350
PharosO75554
Clinical trialWBP4
Miscellaneous
canSAR (ICR)WBP4
HarmonizomeWBP4
DataMed IndexWBP4
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXWBP4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Sep 15 23:36:40 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.