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WDFY1 (WD repeat and FYVE domain containing 1)

Identity

Alias_namesWD40 and FYVE domain containing 1
Alias_symbol (synonym)KIAA1435
FENS-1
WDF1
ZFYVE17
Other alias
HGNC (Hugo) WDFY1
LocusID (NCBI) 57590
Atlas_Id 47234
Location 2q36.1  [Link to chromosome band 2q36]
Location_base_pair Starts at 223875343 and ends at 223945387 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NAV2 (11p15.1) / WDFY1 (2q36.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WDFY1   20451
Cards
Entrez_Gene (NCBI)WDFY1  57590  WD repeat and FYVE domain containing 1
AliasesFENS-1; WDF1; ZFYVE17
GeneCards (Weizmann)WDFY1
Ensembl hg19 (Hinxton)ENSG00000085449 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000085449 [Gene_View]  chr2:223875343-223945387 [Contig_View]  WDFY1 [Vega]
ICGC DataPortalENSG00000085449
TCGA cBioPortalWDFY1
AceView (NCBI)WDFY1
Genatlas (Paris)WDFY1
WikiGenes57590
SOURCE (Princeton)WDFY1
Genetics Home Reference (NIH)WDFY1
Genomic and cartography
GoldenPath hg38 (UCSC)WDFY1  -     chr2:223875343-223945387 -  2q36.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WDFY1  -     2q36.1   [Description]    (hg19-Feb_2009)
EnsemblWDFY1 - 2q36.1 [CytoView hg19]  WDFY1 - 2q36.1 [CytoView hg38]
Mapping of homologs : NCBIWDFY1 [Mapview hg19]  WDFY1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA411290 AB037856 AF411977 AJ310568 AK022888
RefSeq transcript (Entrez)NM_020830
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)WDFY1
Cluster EST : UnigeneHs.368359 [ NCBI ]
CGAP (NCI)Hs.368359
Alternative Splicing GalleryENSG00000085449
Gene ExpressionWDFY1 [ NCBI-GEO ]   WDFY1 [ EBI - ARRAY_EXPRESS ]   WDFY1 [ SEEK ]   WDFY1 [ MEM ]
Gene Expression Viewer (FireBrowse)WDFY1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57590
GTEX Portal (Tissue expression)WDFY1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IWB7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IWB7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IWB7
Splice isoforms : SwissVarQ8IWB7
PhosPhoSitePlusQ8IWB7
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)    ZF_FYVE (PS50178)   
Domains : Interpro (EBI)G-protein_beta_WD-40_rep    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom    Znf_FYVE    Znf_FYVE-rel    Znf_FYVE_PHD    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)FYVE (PF01363)    WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam01363    pfam00400   
Domain families : Smart (EMBL)FYVE (SM00064)  WD40 (SM00320)  
Conserved Domain (NCBI)WDFY1
DMDM Disease mutations57590
Blocks (Seattle)WDFY1
SuperfamilyQ8IWB7
Human Protein AtlasENSG00000085449
Peptide AtlasQ8IWB7
HPRD15663
IPIIPI00024283   IPI00303883   IPI00916648   
Protein Interaction databases
DIP (DOE-UCLA)Q8IWB7
IntAct (EBI)Q8IWB7
FunCoupENSG00000085449
BioGRIDWDFY1
STRING (EMBL)WDFY1
ZODIACWDFY1
Ontologies - Pathways
QuickGOQ8IWB7
Ontology : AmiGOprotein binding  1-phosphatidylinositol binding  nucleus  early endosome  cytosol  biological_process  zinc ion binding  positive regulation of toll-like receptor 3 signaling pathway  positive regulation of toll-like receptor 4 signaling pathway  
Ontology : EGO-EBIprotein binding  1-phosphatidylinositol binding  nucleus  early endosome  cytosol  biological_process  zinc ion binding  positive regulation of toll-like receptor 3 signaling pathway  positive regulation of toll-like receptor 4 signaling pathway  
NDEx NetworkWDFY1
Atlas of Cancer Signalling NetworkWDFY1
Wikipedia pathwaysWDFY1
Orthology - Evolution
OrthoDB57590
GeneTree (enSembl)ENSG00000085449
Phylogenetic Trees/Animal Genes : TreeFamWDFY1
HOVERGENQ8IWB7
HOGENOMQ8IWB7
Homologs : HomoloGeneWDFY1
Homology/Alignments : Family Browser (UCSC)WDFY1
Gene fusions - Rearrangements
Fusion : MitelmanNAV2/WDFY1 [11p15.1/2q36.1]  [t(2;11)(q36;p15)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWDFY1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WDFY1
dbVarWDFY1
ClinVarWDFY1
1000_GenomesWDFY1 
Exome Variant ServerWDFY1
ExAC (Exome Aggregation Consortium)WDFY1 (select the gene name)
Genetic variants : HAPMAP57590
Genomic Variants (DGV)WDFY1 [DGVbeta]
DECIPHERWDFY1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWDFY1 
Mutations
ICGC Data PortalWDFY1 
TCGA Data PortalWDFY1 
Broad Tumor PortalWDFY1
OASIS PortalWDFY1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWDFY1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDWDFY1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WDFY1
DgiDB (Drug Gene Interaction Database)WDFY1
DoCM (Curated mutations)WDFY1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WDFY1 (select a term)
intoGenWDFY1
Cancer3DWDFY1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenWDFY1
Genetic Testing Registry WDFY1
NextProtQ8IWB7 [Medical]
TSGene57590
GENETestsWDFY1
Target ValidationWDFY1
Huge Navigator WDFY1 [HugePedia]
snp3D : Map Gene to Disease57590
BioCentury BCIQWDFY1
ClinGenWDFY1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57590
Chemical/Pharm GKB GenePA134929936
Clinical trialWDFY1
Miscellaneous
canSAR (ICR)WDFY1 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWDFY1
EVEXWDFY1
GoPubMedWDFY1
iHOPWDFY1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 13:02:43 CEST 2017

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