Atlas of Genetics and Cytogenetics in Oncology and Haematology

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WDFY4 (WDFY family member 4)

Identity

Alias (NCBI)C10orf64
HGNC (Hugo) WDFY4
HGNC Alias symbKIAA1607
Em:AC060234.3
FLJ45748
HGNC Previous nameC10orf64
HGNC Previous namechromosome 10 open reading frame 64
LocusID (NCBI) 57705
Atlas_Id 75697
Location 10q11.23  [Link to chromosome band 10q11]
Location_base_pair Starts at 48685473 and ends at 48982956 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ANK3 (10q21.2) / WDFY4 (10q11.22)WDFY4 (10q11.22) / TNRC6A (16p12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(10;10)(q11;q21) ANK3/WDFY4

External links

Nomenclature
HGNC (Hugo)WDFY4   29323
Cards
Entrez_Gene (NCBI)WDFY4    WDFY family member 4
AliasesC10orf64
GeneCards (Weizmann)WDFY4
Ensembl hg19 (Hinxton)ENSG00000128815 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000128815 [Gene_View]  ENSG00000128815 [Sequence]  chr10:48685473-48982956 [Contig_View]  WDFY4 [Vega]
ICGC DataPortalENSG00000128815
TCGA cBioPortalWDFY4
AceView (NCBI)WDFY4
Genatlas (Paris)WDFY4
SOURCE (Princeton)WDFY4
Genetics Home Reference (NIH)WDFY4
Genomic and cartography
GoldenPath hg38 (UCSC)WDFY4  -     chr10:48685473-48982956 +  10q11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WDFY4  -     10q11.23   [Description]    (hg19-Feb_2009)
GoldenPathWDFY4 - 10q11.23 [CytoView hg19]  WDFY4 - 10q11.23 [CytoView hg38]
ImmunoBaseENSG00000128815
genome Data Viewer NCBIWDFY4 [Mapview hg19]  
OMIM613316   
Gene and transcription
Genbank (Entrez)AB046827 AK024502 AK074085 AK074443 AK093607
RefSeq transcript (Entrez)NM_001370153 NM_001370154 NM_020945
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)WDFY4
Alternative Splicing GalleryENSG00000128815
Gene ExpressionWDFY4 [ NCBI-GEO ]   WDFY4 [ EBI - ARRAY_EXPRESS ]   WDFY4 [ SEEK ]   WDFY4 [ MEM ]
Gene Expression Viewer (FireBrowse)WDFY4 [ Firebrowse - Broad ]
GenevisibleExpression of WDFY4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57705
GTEX Portal (Tissue expression)WDFY4
Human Protein AtlasENSG00000128815-WDFY4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZS81   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZS81  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZS81
Splice isoforms : SwissVarQ6ZS81
PhosPhoSitePlusQ6ZS81
Domaine pattern : Prosite (Expaxy)BEACH (PS50197)    PH_BEACH (PS51783)    WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)ARM-type_fold    BEACH_dom    BEACH_dom_sf    PH-BEACH_dom    WD40/YVTN_repeat-like_dom_sf    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom    WD40_repeat_dom_sf   
Domain families : Pfam (Sanger)Beach (PF02138)    WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam02138    pfam00400   
Domain families : Smart (EMBL)Beach (SM01026)  WD40 (SM00320)  
Conserved Domain (NCBI)WDFY4
Blocks (Seattle)WDFY4
SuperfamilyQ6ZS81
Human Protein Atlas [tissue]ENSG00000128815-WDFY4 [tissue]
Peptide AtlasQ6ZS81
IPIIPI00887548   IPI00472883   IPI00914858   IPI00641442   IPI00550834   IPI00910657   IPI01010125   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZS81
IntAct (EBI)Q6ZS81
BioGRIDWDFY4
STRING (EMBL)WDFY4
ZODIACWDFY4
Ontologies - Pathways
QuickGOQ6ZS81
Ontology : AmiGOintegral component of membrane  
Ontology : EGO-EBIintegral component of membrane  
NDEx NetworkWDFY4
Atlas of Cancer Signalling NetworkWDFY4
Wikipedia pathwaysWDFY4
Orthology - Evolution
OrthoDB57705
GeneTree (enSembl)ENSG00000128815
Phylogenetic Trees/Animal Genes : TreeFamWDFY4
HOGENOMQ6ZS81
Homologs : HomoloGeneWDFY4
Homology/Alignments : Family Browser (UCSC)WDFY4
Gene fusions - Rearrangements
Fusion : QuiverWDFY4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWDFY4 [hg38]
dbVarWDFY4
ClinVarWDFY4
MonarchWDFY4
1000_GenomesWDFY4 
Exome Variant ServerWDFY4
GNOMAD BrowserENSG00000128815
Varsome BrowserWDFY4
Genomic Variants (DGV)WDFY4 [DGVbeta]
DECIPHERWDFY4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWDFY4 
Mutations
ICGC Data PortalWDFY4 
TCGA Data PortalWDFY4 
Broad Tumor PortalWDFY4
OASIS PortalWDFY4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWDFY4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DWDFY4
Mutations and Diseases : HGMDWDFY4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WDFY4
DgiDB (Drug Gene Interaction Database)WDFY4
DoCM (Curated mutations)WDFY4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WDFY4 (select a term)
intoGenWDFY4
Cancer3DWDFY4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613316   
Orphanet
DisGeNETWDFY4
MedgenWDFY4
Genetic Testing Registry WDFY4
NextProtQ6ZS81 [Medical]
GENETestsWDFY4
Target ValidationWDFY4
Huge Navigator WDFY4 [HugePedia]
ClinGenWDFY4
Clinical trials, drugs, therapy
MyCancerGenomeWDFY4
Protein Interactions : CTD
Pharm GKB GenePA134967634
Clinical trialWDFY4
Miscellaneous
canSAR (ICR)WDFY4 (select the gene name)
HarmonizomeWDFY4
DataMed IndexWDFY4
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWDFY4
EVEXWDFY4
GoPubMedWDFY4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Dec 5 17:34:43 CET 2020
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