Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

WDPCP (WD repeat containing planar cell polarity effector)

Identity

Alias_namesC2orf86
chromosome 2 open reading frame 86
Alias_symbol (synonym)hFrtz
fritz
BBS15
Other aliasCHDTHP
FRITZ
FRTZ
HGNC (Hugo) WDPCP
LocusID (NCBI) 51057
Atlas_Id 54774
Location 2p15  [Link to chromosome band 2p15]
Location_base_pair Starts at 63121400 and ends at 63438007 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AFTPH (2p14) / WDPCP (2p15)MAP4K3 (2p22.1) / WDPCP (2p15)PPP3R1 (2p14) / WDPCP (2p15)
WDPCP (2p15) / AFTPH (2p14)WDPCP (2p15) / AMBRA1 (11p11.2)WDPCP (2p15) / VPS54 (2p14)
PPP3R1 2p14 / WDPCP 2p15WDPCP 2p15 / VPS54 2p14

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)WDPCP   28027
Cards
Entrez_Gene (NCBI)WDPCP  51057  WD repeat containing planar cell polarity effector
AliasesBBS15; C2orf86; CHDTHP; FRITZ; 
FRTZ
GeneCards (Weizmann)WDPCP
Ensembl hg19 (Hinxton)ENSG00000143951 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000143951 [Gene_View]  chr2:63121400-63438007 [Contig_View]  WDPCP [Vega]
ICGC DataPortalENSG00000143951
TCGA cBioPortalWDPCP
AceView (NCBI)WDPCP
Genatlas (Paris)WDPCP
WikiGenes51057
SOURCE (Princeton)WDPCP
Genetics Home Reference (NIH)WDPCP
Genomic and cartography
GoldenPath hg38 (UCSC)WDPCP  -     chr2:63121400-63438007 -  2p15   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WDPCP  -     2p15   [Description]    (hg19-Feb_2009)
EnsemblWDPCP - 2p15 [CytoView hg19]  WDPCP - 2p15 [CytoView hg38]
Mapping of homologs : NCBIWDPCP [Mapview hg19]  WDPCP [Mapview hg38]
OMIM217085   613580   615992   
Gene and transcription
Genbank (Entrez)AF131737 AK001849 AK022647 AK055030 AK309028
RefSeq transcript (Entrez)NM_001042692 NM_015910
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)WDPCP
Cluster EST : UnigeneHs.414952 [ NCBI ]
CGAP (NCI)Hs.414952
Alternative Splicing GalleryENSG00000143951
Gene ExpressionWDPCP [ NCBI-GEO ]   WDPCP [ EBI - ARRAY_EXPRESS ]   WDPCP [ SEEK ]   WDPCP [ MEM ]
Gene Expression Viewer (FireBrowse)WDPCP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51057
GTEX Portal (Tissue expression)WDPCP
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95876   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95876  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95876
Splice isoforms : SwissVarO95876
PhosPhoSitePlusO95876
Domains : Interpro (EBI)Frtz    WD40/YVTN_repeat-like_dom    WD40_repeat_dom   
Domain families : Pfam (Sanger)Frtz (PF11768)   
Domain families : Pfam (NCBI)pfam11768   
Conserved Domain (NCBI)WDPCP
DMDM Disease mutations51057
Blocks (Seattle)WDPCP
SuperfamilyO95876
Human Protein AtlasENSG00000143951
Peptide AtlasO95876
HPRD14228
IPIIPI00179605   IPI00917705   IPI00783552   IPI00916678   IPI00916119   IPI00916007   IPI00915881   IPI00917329   IPI00974331   
Protein Interaction databases
DIP (DOE-UCLA)O95876
IntAct (EBI)O95876
FunCoupENSG00000143951
BioGRIDWDPCP
STRING (EMBL)WDPCP
ZODIACWDPCP
Ontologies - Pathways
QuickGOO95876
Ontology : AmiGOkidney development  auditory receptor cell morphogenesis  plasma membrane  axoneme  cell cortex  smoothened signaling pathway  regulation of fibroblast migration  apical plasma membrane  regulation of embryonic cell shape  septin cytoskeleton organization  regulation of protein localization  embryonic digit morphogenesis  camera-type eye development  establishment of protein localization  regulation of focal adhesion assembly  digestive system development  palate development  cilium assembly  respiratory system development  cardiovascular system development  glomerular visceral epithelial cell migration  axonemal basal plate  regulation of ruffle assembly  regulation of establishment of cell polarity  
Ontology : EGO-EBIkidney development  auditory receptor cell morphogenesis  plasma membrane  axoneme  cell cortex  smoothened signaling pathway  regulation of fibroblast migration  apical plasma membrane  regulation of embryonic cell shape  septin cytoskeleton organization  regulation of protein localization  embryonic digit morphogenesis  camera-type eye development  establishment of protein localization  regulation of focal adhesion assembly  digestive system development  palate development  cilium assembly  respiratory system development  cardiovascular system development  glomerular visceral epithelial cell migration  axonemal basal plate  regulation of ruffle assembly  regulation of establishment of cell polarity  
NDEx NetworkWDPCP
Atlas of Cancer Signalling NetworkWDPCP
Wikipedia pathwaysWDPCP
Orthology - Evolution
OrthoDB51057
GeneTree (enSembl)ENSG00000143951
Phylogenetic Trees/Animal Genes : TreeFamWDPCP
HOVERGENO95876
HOGENOMO95876
Homologs : HomoloGeneWDPCP
Homology/Alignments : Family Browser (UCSC)WDPCP
Gene fusions - Rearrangements
Fusion: TCGAPPP3R1 2p14 WDPCP 2p15 PRAD
Fusion: TCGAWDPCP 2p15 VPS54 2p14 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWDPCP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WDPCP
dbVarWDPCP
ClinVarWDPCP
1000_GenomesWDPCP 
Exome Variant ServerWDPCP
ExAC (Exome Aggregation Consortium)WDPCP (select the gene name)
Genetic variants : HAPMAP51057
Genomic Variants (DGV)WDPCP [DGVbeta]
DECIPHERWDPCP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWDPCP 
Mutations
ICGC Data PortalWDPCP 
TCGA Data PortalWDPCP 
Broad Tumor PortalWDPCP
OASIS PortalWDPCP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWDPCP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDWDPCP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Eye diseases - LOVD
LOVD (Leiden Open Variation Database)EURO-WABB PROJECT OPEN VARIATION DATABASE
BioMutasearch WDPCP
DgiDB (Drug Gene Interaction Database)WDPCP
DoCM (Curated mutations)WDPCP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WDPCP (select a term)
intoGenWDPCP
Cancer3DWDPCP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM217085    613580    615992   
Orphanet280    1557    3244   
MedgenWDPCP
Genetic Testing Registry WDPCP
NextProtO95876 [Medical]
TSGene51057
GENETestsWDPCP
Huge Navigator WDPCP [HugePedia]
snp3D : Map Gene to Disease51057
BioCentury BCIQWDPCP
ClinGenWDPCP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51057
Chemical/Pharm GKB GenePA164717186
Clinical trialWDPCP
Miscellaneous
canSAR (ICR)WDPCP (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWDPCP
EVEXWDPCP
GoPubMedWDPCP
iHOPWDPCP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:44:02 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.