Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

WDR12 (WD repeat domain 12)

Identity

Alias_symbol (synonym)YTM1
FLJ10881
Other alias
HGNC (Hugo) WDR12
LocusID (NCBI) 55759
Atlas_Id 56456
Location 2q33.2  [Link to chromosome band 2q33]
Location_base_pair Starts at 202880600 and ends at 202912226 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BMPR2 (2q33.1) / WDR12 (2q33.2)PHLPP1 (18q21.33) / WDR12 (2q33.2)WDR12 (2q33.2) / PARD3B (2q33.3)
WDR12 (2q33.2) / VPS52 (6p21.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WDR12   14098
Cards
Entrez_Gene (NCBI)WDR12  55759  WD repeat domain 12
AliasesYTM1
GeneCards (Weizmann)WDR12
Ensembl hg19 (Hinxton)ENSG00000138442 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138442 [Gene_View]  chr2:202880600-202912226 [Contig_View]  WDR12 [Vega]
ICGC DataPortalENSG00000138442
TCGA cBioPortalWDR12
AceView (NCBI)WDR12
Genatlas (Paris)WDR12
WikiGenes55759
SOURCE (Princeton)WDR12
Genetics Home Reference (NIH)WDR12
Genomic and cartography
GoldenPath hg38 (UCSC)WDR12  -     chr2:202880600-202912226 -  2q33.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WDR12  -     2q33.2   [Description]    (hg19-Feb_2009)
EnsemblWDR12 - 2q33.2 [CytoView hg19]  WDR12 - 2q33.2 [CytoView hg38]
Mapping of homologs : NCBIWDR12 [Mapview hg19]  WDR12 [Mapview hg38]
OMIM616620   
Gene and transcription
Genbank (Entrez)AF242546 AK001743 AK022781 AK022782 AK056092
RefSeq transcript (Entrez)NM_018256
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)WDR12
Cluster EST : UnigeneHs.73291 [ NCBI ]
CGAP (NCI)Hs.73291
Alternative Splicing GalleryENSG00000138442
Gene ExpressionWDR12 [ NCBI-GEO ]   WDR12 [ EBI - ARRAY_EXPRESS ]   WDR12 [ SEEK ]   WDR12 [ MEM ]
Gene Expression Viewer (FireBrowse)WDR12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55759
GTEX Portal (Tissue expression)WDR12
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9GZL7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9GZL7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9GZL7
Splice isoforms : SwissVarQ9GZL7
PhosPhoSitePlusQ9GZL7
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)G-protein_beta_WD-40_rep    NLE    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom    WDR12/Ytm1   
Domain families : Pfam (Sanger)NLE (PF08154)    WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam08154    pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)WDR12
DMDM Disease mutations55759
Blocks (Seattle)WDR12
SuperfamilyQ9GZL7
Human Protein AtlasENSG00000138442
Peptide AtlasQ9GZL7
HPRD18295
IPIIPI00304232   
Protein Interaction databases
DIP (DOE-UCLA)Q9GZL7
IntAct (EBI)Q9GZL7
FunCoupENSG00000138442
BioGRIDWDR12
STRING (EMBL)WDR12
ZODIACWDR12
Ontologies - Pathways
QuickGOQ9GZL7
Ontology : AmiGOmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  protein binding  nucleoplasm  nucleoplasm  nucleolus  rRNA processing  Notch signaling pathway  cell proliferation  preribosome, large subunit precursor  ribosomal large subunit biogenesis  PeBoW complex  
Ontology : EGO-EBImaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  protein binding  nucleoplasm  nucleoplasm  nucleolus  rRNA processing  Notch signaling pathway  cell proliferation  preribosome, large subunit precursor  ribosomal large subunit biogenesis  PeBoW complex  
NDEx NetworkWDR12
Atlas of Cancer Signalling NetworkWDR12
Wikipedia pathwaysWDR12
Orthology - Evolution
OrthoDB55759
GeneTree (enSembl)ENSG00000138442
Phylogenetic Trees/Animal Genes : TreeFamWDR12
HOVERGENQ9GZL7
HOGENOMQ9GZL7
Homologs : HomoloGeneWDR12
Homology/Alignments : Family Browser (UCSC)WDR12
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWDR12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WDR12
dbVarWDR12
ClinVarWDR12
1000_GenomesWDR12 
Exome Variant ServerWDR12
ExAC (Exome Aggregation Consortium)WDR12 (select the gene name)
Genetic variants : HAPMAP55759
Genomic Variants (DGV)WDR12 [DGVbeta]
DECIPHERWDR12 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWDR12 
Mutations
ICGC Data PortalWDR12 
TCGA Data PortalWDR12 
Broad Tumor PortalWDR12
OASIS PortalWDR12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWDR12  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDWDR12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WDR12
DgiDB (Drug Gene Interaction Database)WDR12
DoCM (Curated mutations)WDR12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WDR12 (select a term)
intoGenWDR12
Cancer3DWDR12(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616620   
Orphanet
MedgenWDR12
Genetic Testing Registry WDR12
NextProtQ9GZL7 [Medical]
TSGene55759
GENETestsWDR12
Target ValidationWDR12
Huge Navigator WDR12 [HugePedia]
snp3D : Map Gene to Disease55759
BioCentury BCIQWDR12
ClinGenWDR12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55759
Chemical/Pharm GKB GenePA37841
Clinical trialWDR12
Miscellaneous
canSAR (ICR)WDR12 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWDR12
EVEXWDR12
GoPubMedWDR12
iHOPWDR12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 13:02:45 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.