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WDR3 (WD repeat domain 3)

Identity

Alias_symbol (synonym)FLJ12796
UTP12
DIP2
Other alias
HGNC (Hugo) WDR3
LocusID (NCBI) 10885
Atlas_Id 51576
Location 1p12  [Link to chromosome band 1p12]
Location_base_pair Starts at 117929749 and ends at 117960426 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CELF2 (10p14) / WDR3 (1p12)CEPT1 (1p13.3) / WDR3 (1p12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WDR3   12755
Cards
Entrez_Gene (NCBI)WDR3  10885  WD repeat domain 3
AliasesDIP2; UTP12
GeneCards (Weizmann)WDR3
Ensembl hg19 (Hinxton)ENSG00000065183 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000065183 [Gene_View]  chr1:117929749-117960426 [Contig_View]  WDR3 [Vega]
ICGC DataPortalENSG00000065183
TCGA cBioPortalWDR3
AceView (NCBI)WDR3
Genatlas (Paris)WDR3
WikiGenes10885
SOURCE (Princeton)WDR3
Genetics Home Reference (NIH)WDR3
Genomic and cartography
GoldenPath hg38 (UCSC)WDR3  -     chr1:117929749-117960426 +  1p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WDR3  -     1p12   [Description]    (hg19-Feb_2009)
EnsemblWDR3 - 1p12 [CytoView hg19]  WDR3 - 1p12 [CytoView hg38]
Mapping of homologs : NCBIWDR3 [Mapview hg19]  WDR3 [Mapview hg38]
OMIM604737   
Gene and transcription
Genbank (Entrez)AA258068 AB209201 AF083217 AK022858 AK292438
RefSeq transcript (Entrez)NM_006784
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)WDR3
Cluster EST : UnigeneHs.310809 [ NCBI ]
CGAP (NCI)Hs.310809
Alternative Splicing GalleryENSG00000065183
Gene ExpressionWDR3 [ NCBI-GEO ]   WDR3 [ EBI - ARRAY_EXPRESS ]   WDR3 [ SEEK ]   WDR3 [ MEM ]
Gene Expression Viewer (FireBrowse)WDR3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10885
GTEX Portal (Tissue expression)WDR3
Human Protein AtlasENSG00000065183-WDR3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UNX4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UNX4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UNX4
Splice isoforms : SwissVarQ9UNX4
PhosPhoSitePlusQ9UNX4
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)Apc4_WD40_dom    G-protein_beta_WD-40_rep    SSU_processome_Utp12    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)ANAPC4_WD40 (PF12894)    Utp12 (PF04003)    WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam12894    pfam04003    pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)WDR3
DMDM Disease mutations10885
Blocks (Seattle)WDR3
SuperfamilyQ9UNX4
Human Protein Atlas [tissue]ENSG00000065183-WDR3 [tissue]
Peptide AtlasQ9UNX4
HPRD16066
IPIIPI00009471   IPI00447116   
Protein Interaction databases
DIP (DOE-UCLA)Q9UNX4
IntAct (EBI)Q9UNX4
FunCoupENSG00000065183
BioGRIDWDR3
STRING (EMBL)WDR3
ZODIACWDR3
Ontologies - Pathways
QuickGOQ9UNX4
Ontology : AmiGOmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  RNA binding  nucleus  nucleoplasm  nucleolus  rRNA processing  snoRNA binding  nuclear membrane  small-subunit processome  Pwp2p-containing subcomplex of 90S preribosome  
Ontology : EGO-EBImaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  RNA binding  nucleus  nucleoplasm  nucleolus  rRNA processing  snoRNA binding  nuclear membrane  small-subunit processome  Pwp2p-containing subcomplex of 90S preribosome  
Pathways : KEGGRibosome biogenesis in eukaryotes   
NDEx NetworkWDR3
Atlas of Cancer Signalling NetworkWDR3
Wikipedia pathwaysWDR3
Orthology - Evolution
OrthoDB10885
GeneTree (enSembl)ENSG00000065183
Phylogenetic Trees/Animal Genes : TreeFamWDR3
HOVERGENQ9UNX4
HOGENOMQ9UNX4
Homologs : HomoloGeneWDR3
Homology/Alignments : Family Browser (UCSC)WDR3
Gene fusions - Rearrangements
Fusion : MitelmanCEPT1/WDR3 [1p13.3/1p12]  [t(1;1)(p12;p13)]  
Tumor Fusion PortalWDR3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWDR3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WDR3
dbVarWDR3
ClinVarWDR3
1000_GenomesWDR3 
Exome Variant ServerWDR3
ExAC (Exome Aggregation Consortium)ENSG00000065183
GNOMAD BrowserENSG00000065183
Genetic variants : HAPMAP10885
Genomic Variants (DGV)WDR3 [DGVbeta]
DECIPHERWDR3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWDR3 
Mutations
ICGC Data PortalWDR3 
TCGA Data PortalWDR3 
Broad Tumor PortalWDR3
OASIS PortalWDR3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWDR3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDWDR3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WDR3
DgiDB (Drug Gene Interaction Database)WDR3
DoCM (Curated mutations)WDR3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WDR3 (select a term)
intoGenWDR3
Cancer3DWDR3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604737   
Orphanet
DisGeNETWDR3
MedgenWDR3
Genetic Testing Registry WDR3
NextProtQ9UNX4 [Medical]
TSGene10885
GENETestsWDR3
Target ValidationWDR3
Huge Navigator WDR3 [HugePedia]
snp3D : Map Gene to Disease10885
BioCentury BCIQWDR3
ClinGenWDR3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10885
Chemical/Pharm GKB GenePA37359
Clinical trialWDR3
Miscellaneous
canSAR (ICR)WDR3 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWDR3
EVEXWDR3
GoPubMedWDR3
iHOPWDR3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:41:35 CET 2017

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