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WDR35 (WD repeat domain 35)

Identity

Other aliasCED2
IFT121
IFTA1
SRTD7
HGNC (Hugo) WDR35
LocusID (NCBI) 57539
Atlas_Id 56670
Location 2p24.1  [Link to chromosome band 2p24]
Location_base_pair Starts at 19910266 and ends at 19990123 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GTF3C2 (2p23.3) / WDR35 (2p24.1)WDR35 (2p24.1) / PUM2 (2p24.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WDR35   29250
Cards
Entrez_Gene (NCBI)WDR35  57539  WD repeat domain 35
AliasesCED2; IFT121; IFTA1; SRTD7
GeneCards (Weizmann)WDR35
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr2:19910266-19990123 [Contig_View]  WDR35 [Vega]
TCGA cBioPortalWDR35
AceView (NCBI)WDR35
Genatlas (Paris)WDR35
WikiGenes57539
SOURCE (Princeton)WDR35
Genetics Home Reference (NIH)WDR35
Genomic and cartography
GoldenPath hg38 (UCSC)WDR35  -     chr2:19910266-19990123 -  2p24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WDR35  -     2p24.1   [Description]    (hg19-Feb_2009)
EnsemblWDR35 - 2p24.1 [CytoView hg19]  WDR35 - 2p24.1 [CytoView hg38]
Mapping of homologs : NCBIWDR35 [Mapview hg19]  WDR35 [Mapview hg38]
OMIM613602   613610   614091   
Gene and transcription
Genbank (Entrez)AB037757 AK022866 AK091205 AK122917 AK315094
RefSeq transcript (Entrez)NM_001006657 NM_020779
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)WDR35
Cluster EST : UnigeneHs.205427 [ NCBI ]
CGAP (NCI)Hs.205427
Gene ExpressionWDR35 [ NCBI-GEO ]   WDR35 [ EBI - ARRAY_EXPRESS ]   WDR35 [ SEEK ]   WDR35 [ MEM ]
Gene Expression Viewer (FireBrowse)WDR35 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57539
GTEX Portal (Tissue expression)WDR35
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P2L0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P2L0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P2L0
Splice isoforms : SwissVarQ9P2L0
PhosPhoSitePlusQ9P2L0
Domaine pattern : Prosite (Expaxy)WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)Apc4_WD40_dom    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_dom    WDR35   
Domain families : Pfam (Sanger)ANAPC4_WD40 (PF12894)   
Domain families : Pfam (NCBI)pfam12894   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)WDR35
DMDM Disease mutations57539
Blocks (Seattle)WDR35
SuperfamilyQ9P2L0
Peptide AtlasQ9P2L0
IPIIPI00165984   IPI00172480   IPI00902440   IPI00893728   IPI00893877   
Protein Interaction databases
DIP (DOE-UCLA)Q9P2L0
IntAct (EBI)Q9P2L0
BioGRIDWDR35
STRING (EMBL)WDR35
ZODIACWDR35
Ontologies - Pathways
QuickGOQ9P2L0
Ontology : AmiGOcytoplasm  centrosome  cilium  cilium  axoneme  response to toxic substance  negative regulation of gene expression  intraciliary transport particle A  response to lipopolysaccharide  phosphatidylinositol binding  intraciliary retrograde transport  intraciliary transport involved in cilium assembly  ciliary basal body  positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  negative regulation of nitric oxide biosynthetic process  cilium assembly  protein localization to cilium  cellular response to glucose stimulus  cellular response to tumor necrosis factor  positive regulation of release of cytochrome c from mitochondria  liver regeneration  ciliary tip  negative regulation of blood vessel diameter  cellular response to paclitaxel  
Ontology : EGO-EBIcytoplasm  centrosome  cilium  cilium  axoneme  response to toxic substance  negative regulation of gene expression  intraciliary transport particle A  response to lipopolysaccharide  phosphatidylinositol binding  intraciliary retrograde transport  intraciliary transport involved in cilium assembly  ciliary basal body  positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  negative regulation of nitric oxide biosynthetic process  cilium assembly  protein localization to cilium  cellular response to glucose stimulus  cellular response to tumor necrosis factor  positive regulation of release of cytochrome c from mitochondria  liver regeneration  ciliary tip  negative regulation of blood vessel diameter  cellular response to paclitaxel  
NDEx NetworkWDR35
Atlas of Cancer Signalling NetworkWDR35
Wikipedia pathwaysWDR35
Orthology - Evolution
OrthoDB57539
Phylogenetic Trees/Animal Genes : TreeFamWDR35
HOVERGENQ9P2L0
HOGENOMQ9P2L0
Homologs : HomoloGeneWDR35
Homology/Alignments : Family Browser (UCSC)WDR35
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWDR35 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WDR35
dbVarWDR35
ClinVarWDR35
1000_GenomesWDR35 
Exome Variant ServerWDR35
ExAC (Exome Aggregation Consortium)WDR35 (select the gene name)
Genetic variants : HAPMAP57539
Genomic Variants (DGV)WDR35 [DGVbeta]
DECIPHERWDR35 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWDR35 
Mutations
ICGC Data PortalWDR35 
TCGA Data PortalWDR35 
Broad Tumor PortalWDR35
OASIS PortalWDR35 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWDR35  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDWDR35
BioMutasearch WDR35
DgiDB (Drug Gene Interaction Database)WDR35
DoCM (Curated mutations)WDR35 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WDR35 (select a term)
intoGenWDR35
Cancer3DWDR35(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613602    613610    614091   
Orphanet
MedgenWDR35
Genetic Testing Registry WDR35
NextProtQ9P2L0 [Medical]
TSGene57539
GENETestsWDR35
Target ValidationWDR35
Huge Navigator WDR35 [HugePedia]
snp3D : Map Gene to Disease57539
BioCentury BCIQWDR35
ClinGenWDR35
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57539
Chemical/Pharm GKB GenePA134928987
Clinical trialWDR35
Miscellaneous
canSAR (ICR)WDR35 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWDR35
EVEXWDR35
GoPubMedWDR35
iHOPWDR35
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 13:02:47 CEST 2017

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