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WDR45B (WD repeat domain 45B)

Identity

Alias_namesWDR45L
WDR45-like
Alias_symbol (synonym)WIPI3
Other aliasWIPI-3
HGNC (Hugo) WDR45B
LocusID (NCBI) 56270
Atlas_Id 75716
Location 17q25.3  [Link to chromosome band 17q25]
Location_base_pair Starts at 82614562 and ends at 82648535 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
OGFOD3 (17q25.3) / WDR45B (17q25.3)WDR45B (17q25.3) / B3GNTL1 (17q25.3)WDR45B (17q25.3) / C17orf62 (17q25.3)
WDR45B (17q25.3) / RAB40B (17q25.3)WDR45B (17q25.3) / SEPT4 (17q22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WDR45B   25072
Cards
Entrez_Gene (NCBI)WDR45B  56270  WD repeat domain 45B
AliasesWDR45L; WIPI-3; WIPI3
GeneCards (Weizmann)WDR45B
Ensembl hg19 (Hinxton)ENSG00000141580 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000141580 [Gene_View]  chr17:82614562-82648535 [Contig_View]  WDR45B [Vega]
ICGC DataPortalENSG00000141580
TCGA cBioPortalWDR45B
AceView (NCBI)WDR45B
Genatlas (Paris)WDR45B
WikiGenes56270
SOURCE (Princeton)WDR45B
Genetics Home Reference (NIH)WDR45B
Genomic and cartography
GoldenPath hg38 (UCSC)WDR45B  -     chr17:82614562-82648535 -  17q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WDR45B  -     17q25.3   [Description]    (hg19-Feb_2009)
EnsemblWDR45B - 17q25.3 [CytoView hg19]  WDR45B - 17q25.3 [CytoView hg38]
Mapping of homologs : NCBIWDR45B [Mapview hg19]  WDR45B [Mapview hg38]
OMIM609226   
Gene and transcription
Genbank (Entrez)AA861045 AF091083 AK297477 AM182326 AY691427
RefSeq transcript (Entrez)NM_019613
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)WDR45B
Cluster EST : UnigeneHs.132161 [ NCBI ]
CGAP (NCI)Hs.132161
Alternative Splicing GalleryENSG00000141580
Gene ExpressionWDR45B [ NCBI-GEO ]   WDR45B [ EBI - ARRAY_EXPRESS ]   WDR45B [ SEEK ]   WDR45B [ MEM ]
Gene Expression Viewer (FireBrowse)WDR45B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56270
GTEX Portal (Tissue expression)WDR45B
Human Protein AtlasENSG00000141580-WDR45B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5MNZ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5MNZ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5MNZ6
Splice isoforms : SwissVarQ5MNZ6
PhosPhoSitePlusQ5MNZ6
Domains : Interpro (EBI)WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)WDR45B
DMDM Disease mutations56270
Blocks (Seattle)WDR45B
SuperfamilyQ5MNZ6
Human Protein Atlas [tissue]ENSG00000141580-WDR45B [tissue]
Peptide AtlasQ5MNZ6
HPRD15669
IPIIPI00021329   IPI01014836   
Protein Interaction databases
DIP (DOE-UCLA)Q5MNZ6
IntAct (EBI)Q5MNZ6
FunCoupENSG00000141580
BioGRIDWDR45B
STRING (EMBL)WDR45B
ZODIACWDR45B
Ontologies - Pathways
QuickGOQ5MNZ6
Ontology : AmiGO
Ontology : EGO-EBI
NDEx NetworkWDR45B
Atlas of Cancer Signalling NetworkWDR45B
Wikipedia pathwaysWDR45B
Orthology - Evolution
OrthoDB56270
GeneTree (enSembl)ENSG00000141580
Phylogenetic Trees/Animal Genes : TreeFamWDR45B
HOVERGENQ5MNZ6
HOGENOMQ5MNZ6
Homologs : HomoloGeneWDR45B
Homology/Alignments : Family Browser (UCSC)WDR45B
Gene fusions - Rearrangements
Fusion: Tumor Portal WDR45B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWDR45B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WDR45B
dbVarWDR45B
ClinVarWDR45B
1000_GenomesWDR45B 
Exome Variant ServerWDR45B
ExAC (Exome Aggregation Consortium)ENSG00000141580
GNOMAD BrowserENSG00000141580
Genetic variants : HAPMAP56270
Genomic Variants (DGV)WDR45B [DGVbeta]
DECIPHERWDR45B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWDR45B 
Mutations
ICGC Data PortalWDR45B 
TCGA Data PortalWDR45B 
Broad Tumor PortalWDR45B
OASIS PortalWDR45B [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDWDR45B
BioMutasearch WDR45B
DgiDB (Drug Gene Interaction Database)WDR45B
DoCM (Curated mutations)WDR45B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WDR45B (select a term)
intoGenWDR45B
Cancer3DWDR45B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609226   
Orphanet
MedgenWDR45B
Genetic Testing Registry WDR45B
NextProtQ5MNZ6 [Medical]
TSGene56270
GENETestsWDR45B
Target ValidationWDR45B
Huge Navigator WDR45B [HugePedia]
snp3D : Map Gene to Disease56270
BioCentury BCIQWDR45B
ClinGenWDR45B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56270
Chemical/Pharm GKB GenePA134894387
Clinical trialWDR45B
Miscellaneous
canSAR (ICR)WDR45B (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWDR45B
EVEXWDR45B
GoPubMedWDR45B
iHOPWDR45B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:35:44 CET 2017

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