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WDR45B (WD repeat domain 45B)

Identity

Alias_namesWDR45L
WDR45-like
Alias_symbol (synonym)WIPI3
Other aliasWIPI-3
HGNC (Hugo) WDR45B
LocusID (NCBI) 56270
Atlas_Id 75716
Location 17q25.3  [Link to chromosome band 17q25]
Location_base_pair Starts at 80572438 and ends at 80606411 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
OGFOD3 (17q25.3) / WDR45B (17q25.3)WDR45B (17q25.3) / B3GNTL1 (17q25.3)WDR45B (17q25.3) / C17orf62 (17q25.3)
WDR45B (17q25.3) / RAB40B (17q25.3)WDR45B (17q25.3) / SEPT4 (17q22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WDR45B   25072
Cards
Entrez_Gene (NCBI)WDR45B  56270  WD repeat domain 45B
AliasesWDR45L; WIPI-3; WIPI3
GeneCards (Weizmann)WDR45B
Ensembl hg19 (Hinxton)ENSG00000141580 [Gene_View]  chr17:80572438-80606411 [Contig_View]  WDR45B [Vega]
Ensembl hg38 (Hinxton)ENSG00000141580 [Gene_View]  chr17:80572438-80606411 [Contig_View]  WDR45B [Vega]
ICGC DataPortalENSG00000141580
TCGA cBioPortalWDR45B
AceView (NCBI)WDR45B
Genatlas (Paris)WDR45B
WikiGenes56270
SOURCE (Princeton)WDR45B
Genetics Home Reference (NIH)WDR45B
Genomic and cartography
GoldenPath hg19 (UCSC)WDR45B  -     chr17:80572438-80606411 -  17q25.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)WDR45B  -     17q25.3   [Description]    (hg38-Dec_2013)
EnsemblWDR45B - 17q25.3 [CytoView hg19]  WDR45B - 17q25.3 [CytoView hg38]
Mapping of homologs : NCBIWDR45B [Mapview hg19]  WDR45B [Mapview hg38]
OMIM609226   
Gene and transcription
Genbank (Entrez)AA861045 AF091083 AK297477 AM182326 AY691427
RefSeq transcript (Entrez)NM_019613
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010663 NW_004929408
Consensus coding sequences : CCDS (NCBI)WDR45B
Cluster EST : UnigeneHs.132161 [ NCBI ]
CGAP (NCI)Hs.132161
Alternative Splicing GalleryENSG00000141580
Gene ExpressionWDR45B [ NCBI-GEO ]   WDR45B [ EBI - ARRAY_EXPRESS ]   WDR45B [ SEEK ]   WDR45B [ MEM ]
Gene Expression Viewer (FireBrowse)WDR45B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56270
GTEX Portal (Tissue expression)WDR45B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5MNZ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5MNZ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5MNZ6
Splice isoforms : SwissVarQ5MNZ6
PhosPhoSitePlusQ5MNZ6
Domains : Interpro (EBI)WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_dom   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)WDR45B
DMDM Disease mutations56270
Blocks (Seattle)WDR45B
SuperfamilyQ5MNZ6
Human Protein AtlasENSG00000141580
Peptide AtlasQ5MNZ6
HPRD15669
IPIIPI00021329   IPI01014836   
Protein Interaction databases
DIP (DOE-UCLA)Q5MNZ6
IntAct (EBI)Q5MNZ6
FunCoupENSG00000141580
BioGRIDWDR45B
STRING (EMBL)WDR45B
ZODIACWDR45B
Ontologies - Pathways
QuickGOQ5MNZ6
Ontology : AmiGOautophagosome assembly  mitochondrion degradation  cytosol  protein lipidation  cellular response to nitrogen starvation  extrinsic component of membrane  phosphatidylinositol-3-phosphate binding  pre-autophagosomal structure membrane  protein localization to pre-autophagosomal structure  nucleophagy  phosphatidylinositol-3,5-bisphosphate binding  
Ontology : EGO-EBIautophagosome assembly  mitochondrion degradation  cytosol  protein lipidation  cellular response to nitrogen starvation  extrinsic component of membrane  phosphatidylinositol-3-phosphate binding  pre-autophagosomal structure membrane  protein localization to pre-autophagosomal structure  nucleophagy  phosphatidylinositol-3,5-bisphosphate binding  
NDEx NetworkWDR45B
Atlas of Cancer Signalling NetworkWDR45B
Wikipedia pathwaysWDR45B
Orthology - Evolution
OrthoDB56270
GeneTree (enSembl)ENSG00000141580
Phylogenetic Trees/Animal Genes : TreeFamWDR45B
HOVERGENQ5MNZ6
HOGENOMQ5MNZ6
Homologs : HomoloGeneWDR45B
Homology/Alignments : Family Browser (UCSC)WDR45B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWDR45B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WDR45B
dbVarWDR45B
ClinVarWDR45B
1000_GenomesWDR45B 
Exome Variant ServerWDR45B
ExAC (Exome Aggregation Consortium)WDR45B (select the gene name)
Genetic variants : HAPMAP56270
Genomic Variants (DGV)WDR45B [DGVbeta]
DECIPHER (Syndromes)17:80572438-80606411  ENSG00000141580
CONAN: Copy Number AnalysisWDR45B 
Mutations
ICGC Data PortalWDR45B 
TCGA Data PortalWDR45B 
Broad Tumor PortalWDR45B
OASIS PortalWDR45B [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDWDR45B
BioMutasearch WDR45B
DgiDB (Drug Gene Interaction Database)WDR45B
DoCM (Curated mutations)WDR45B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WDR45B (select a term)
intoGenWDR45B
Cancer3DWDR45B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609226   
Orphanet
MedgenWDR45B
Genetic Testing Registry WDR45B
NextProtQ5MNZ6 [Medical]
TSGene56270
GENETestsWDR45B
Huge Navigator WDR45B [HugePedia]
snp3D : Map Gene to Disease56270
BioCentury BCIQWDR45B
ClinGenWDR45B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56270
Chemical/Pharm GKB GenePA134894387
Clinical trialWDR45B
Miscellaneous
canSAR (ICR)WDR45B (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWDR45B
EVEXWDR45B
GoPubMedWDR45B
iHOPWDR45B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:51:36 CET 2017

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