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WDR46 (WD repeat domain 46)

Identity

Alias_namesC6orf11
chromosome 6 open reading frame 11
Alias_symbol (synonym)BING4
UTP7
Other aliasFP221
HGNC (Hugo) WDR46
LocusID (NCBI) 9277
Atlas_Id 75717
Location 6p21.32  [Link to chromosome band 6p21]
Location_base_pair Starts at 33279103 and ends at 33289527 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SLC13A4 (7q33) / WDR46 (6p21.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WDR46   13923
Cards
Entrez_Gene (NCBI)WDR46  9277  WD repeat domain 46
AliasesBING4; C6orf11; FP221; UTP7
GeneCards (Weizmann)WDR46
Ensembl hg19 (Hinxton)ENSG00000227057 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000227057 [Gene_View]  chr6:33279103-33289527 [Contig_View]  WDR46 [Vega]
ICGC DataPortalENSG00000227057
TCGA cBioPortalWDR46
AceView (NCBI)WDR46
Genatlas (Paris)WDR46
WikiGenes9277
SOURCE (Princeton)WDR46
Genetics Home Reference (NIH)WDR46
Genomic and cartography
GoldenPath hg38 (UCSC)WDR46  -     chr6:33279103-33289527 -  6p21.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WDR46  -     6p21.32   [Description]    (hg19-Feb_2009)
EnsemblWDR46 - 6p21.32 [CytoView hg19]  WDR46 - 6p21.32 [CytoView hg38]
Mapping of homologs : NCBIWDR46 [Mapview hg19]  WDR46 [Mapview hg38]
OMIM611440   
Gene and transcription
Genbank (Entrez)AF447870 AI867295 AK292171 AK292616 AK297925
RefSeq transcript (Entrez)NM_001164267 NM_005452
RefSeq genomic (Entrez)NC_000006 NC_018917 NT_113891 NT_167245 NT_167247 NT_167248
Consensus coding sequences : CCDS (NCBI)WDR46
Cluster EST : UnigeneHs.671763 [ NCBI ]
CGAP (NCI)Hs.671763
Alternative Splicing GalleryENSG00000227057
Gene ExpressionWDR46 [ NCBI-GEO ]   WDR46 [ EBI - ARRAY_EXPRESS ]   WDR46 [ SEEK ]   WDR46 [ MEM ]
Gene Expression Viewer (FireBrowse)WDR46 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9277
GTEX Portal (Tissue expression)WDR46
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15213   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15213  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15213
Splice isoforms : SwissVarO15213
PhosPhoSitePlusO15213
Domaine pattern : Prosite (Expaxy)WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)BING4_C_dom    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_dom   
Domain families : Pfam (Sanger)BING4CT (PF08149)   
Domain families : Pfam (NCBI)pfam08149   
Domain families : Smart (EMBL)BING4CT (SM01033)  WD40 (SM00320)  
Conserved Domain (NCBI)WDR46
DMDM Disease mutations9277
Blocks (Seattle)WDR46
SuperfamilyO15213
Human Protein AtlasENSG00000227057
Peptide AtlasO15213
HPRD12839
IPIIPI00023126   IPI00641552   IPI00973071   IPI00969401   IPI00797823   
Protein Interaction databases
DIP (DOE-UCLA)O15213
IntAct (EBI)O15213
FunCoupENSG00000227057
BioGRIDWDR46
STRING (EMBL)WDR46
ZODIACWDR46
Ontologies - Pathways
QuickGOO15213
Ontology : AmiGOmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  RNA binding  cellular_component  nucleoplasm  nucleolus  rRNA processing  biological_process  90S preribosome  small-subunit processome  positive regulation of protein targeting to mitochondrion  
Ontology : EGO-EBImaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  RNA binding  cellular_component  nucleoplasm  nucleolus  rRNA processing  biological_process  90S preribosome  small-subunit processome  positive regulation of protein targeting to mitochondrion  
NDEx NetworkWDR46
Atlas of Cancer Signalling NetworkWDR46
Wikipedia pathwaysWDR46
Orthology - Evolution
OrthoDB9277
GeneTree (enSembl)ENSG00000227057
Phylogenetic Trees/Animal Genes : TreeFamWDR46
HOVERGENO15213
HOGENOMO15213
Homologs : HomoloGeneWDR46
Homology/Alignments : Family Browser (UCSC)WDR46
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWDR46 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WDR46
dbVarWDR46
ClinVarWDR46
1000_GenomesWDR46 
Exome Variant ServerWDR46
ExAC (Exome Aggregation Consortium)WDR46 (select the gene name)
Genetic variants : HAPMAP9277
Genomic Variants (DGV)WDR46 [DGVbeta]
DECIPHERWDR46 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWDR46 
Mutations
ICGC Data PortalWDR46 
TCGA Data PortalWDR46 
Broad Tumor PortalWDR46
OASIS PortalWDR46 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWDR46  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDWDR46
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WDR46
DgiDB (Drug Gene Interaction Database)WDR46
DoCM (Curated mutations)WDR46 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WDR46 (select a term)
intoGenWDR46
Cancer3DWDR46(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611440   
Orphanet
MedgenWDR46
Genetic Testing Registry WDR46
NextProtO15213 [Medical]
TSGene9277
GENETestsWDR46
Target ValidationWDR46
Huge Navigator WDR46 [HugePedia]
snp3D : Map Gene to Disease9277
BioCentury BCIQWDR46
ClinGenWDR46
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9277
Chemical/Pharm GKB GenePA25924
Clinical trialWDR46
Miscellaneous
canSAR (ICR)WDR46 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWDR46
EVEXWDR46
GoPubMedWDR46
iHOPWDR46
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:43:47 CEST 2017

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