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WDR59 (WD repeat domain 59)

Identity

Alias_symbol (synonym)FLJ12270
Other aliasFP977
HGNC (Hugo) WDR59
LocusID (NCBI) 79726
Atlas_Id 75721
Location 16q23.1  [Link to chromosome band 16q23]
Location_base_pair Starts at 74907471 and ends at 75019017 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ATP6V0A1 (17q21.2) / WDR59 (16q23.1)GAS8 (16q24.3) / WDR59 (16q23.1)NT5DC1 (6q22.1) / WDR59 (16q23.1)
PRDX1 (1p34.1) / WDR59 (16q23.1)WDR59 (16q23.1) / ASB9 (Xp22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WDR59   25706
Cards
Entrez_Gene (NCBI)WDR59  79726  WD repeat domain 59
AliasesFP977
GeneCards (Weizmann)WDR59
Ensembl hg19 (Hinxton) [Gene_View]  chr16:74907471-75019017 [Contig_View]  WDR59 [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr16:74907471-75019017 [Contig_View]  WDR59 [Vega]
TCGA cBioPortalWDR59
AceView (NCBI)WDR59
Genatlas (Paris)WDR59
WikiGenes79726
SOURCE (Princeton)WDR59
Genetics Home Reference (NIH)WDR59
Genomic and cartography
GoldenPath hg19 (UCSC)WDR59  -     chr16:74907471-75019017 -  16q23.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)WDR59  -     16q23.1   [Description]    (hg38-Dec_2013)
EnsemblWDR59 - 16q23.1 [CytoView hg19]  WDR59 - 16q23.1 [CytoView hg38]
Mapping of homologs : NCBIWDR59 [Mapview hg19]  WDR59 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB067510 AF370390 AK022332 AK091316 AK302557
RefSeq transcript (Entrez)NM_030581
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)WDR59
Cluster EST : UnigeneHs.280951 [ NCBI ]
CGAP (NCI)Hs.280951
Gene ExpressionWDR59 [ NCBI-GEO ]   WDR59 [ EBI - ARRAY_EXPRESS ]   WDR59 [ SEEK ]   WDR59 [ MEM ]
Gene Expression Viewer (FireBrowse)WDR59 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79726
GTEX Portal (Tissue expression)WDR59
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PJI9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6PJI9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6PJI9
Splice isoforms : SwissVarQ6PJI9
PhosPhoSitePlusQ6PJI9
Domaine pattern : Prosite (Expaxy)RWD (PS50908)    WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)RWD-domain    UBQ-conjugating_enzyme/RWD    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)RWD (SM00591)  WD40 (SM00320)  
Conserved Domain (NCBI)WDR59
DMDM Disease mutations79726
Blocks (Seattle)WDR59
SuperfamilyQ6PJI9
Peptide AtlasQ6PJI9
HPRD13351
IPIIPI00242841   IPI00012257   IPI00646489   IPI00644331   IPI01018268   
Protein Interaction databases
DIP (DOE-UCLA)Q6PJI9
IntAct (EBI)Q6PJI9
BioGRIDWDR59
STRING (EMBL)WDR59
ZODIACWDR59
Ontologies - Pathways
QuickGOQ6PJI9
Ontology : AmiGOmolecular_function  cellular_component  biological_process  positive regulation of TOR signaling  cellular response to amino acid starvation  GATOR2 complex  
Ontology : EGO-EBImolecular_function  cellular_component  biological_process  positive regulation of TOR signaling  cellular response to amino acid starvation  GATOR2 complex  
NDEx NetworkWDR59
Atlas of Cancer Signalling NetworkWDR59
Wikipedia pathwaysWDR59
Orthology - Evolution
OrthoDB79726
Phylogenetic Trees/Animal Genes : TreeFamWDR59
HOVERGENQ6PJI9
HOGENOMQ6PJI9
Homologs : HomoloGeneWDR59
Homology/Alignments : Family Browser (UCSC)WDR59
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWDR59 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WDR59
dbVarWDR59
ClinVarWDR59
1000_GenomesWDR59 
Exome Variant ServerWDR59
ExAC (Exome Aggregation Consortium)WDR59 (select the gene name)
Genetic variants : HAPMAP79726
Genomic Variants (DGV)WDR59 [DGVbeta]
DECIPHER (Syndromes)16:74907471-75019017  
CONAN: Copy Number AnalysisWDR59 
Mutations
ICGC Data PortalWDR59 
TCGA Data PortalWDR59 
Broad Tumor PortalWDR59
OASIS PortalWDR59 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWDR59  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDWDR59
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WDR59
DgiDB (Drug Gene Interaction Database)WDR59
DoCM (Curated mutations)WDR59 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WDR59 (select a term)
intoGenWDR59
Cancer3DWDR59(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenWDR59
Genetic Testing Registry WDR59
NextProtQ6PJI9 [Medical]
TSGene79726
GENETestsWDR59
Huge Navigator WDR59 [HugePedia]
snp3D : Map Gene to Disease79726
BioCentury BCIQWDR59
ClinGenWDR59
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79726
Chemical/Pharm GKB GenePA142670593
Clinical trialWDR59
Miscellaneous
canSAR (ICR)WDR59 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWDR59
EVEXWDR59
GoPubMedWDR59
iHOPWDR59
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:51:37 CET 2017

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