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WDR5B (WD repeat domain 5B)

Identity

Alias_symbol (synonym)FLJ11287
Other alias-
HGNC (Hugo) WDR5B
LocusID (NCBI) 54554
Atlas_Id 75722
Location 3q21.1  [Link to chromosome band 3q21]
Location_base_pair Starts at 122411853 and ends at 122416035 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WDR5B   17826
Cards
Entrez_Gene (NCBI)WDR5B  54554  WD repeat domain 5B
Aliases
GeneCards (Weizmann)WDR5B
Ensembl hg19 (Hinxton)ENSG00000196981 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000196981 [Gene_View]  chr3:122411853-122416035 [Contig_View]  WDR5B [Vega]
ICGC DataPortalENSG00000196981
TCGA cBioPortalWDR5B
AceView (NCBI)WDR5B
Genatlas (Paris)WDR5B
WikiGenes54554
SOURCE (Princeton)WDR5B
Genetics Home Reference (NIH)WDR5B
Genomic and cartography
GoldenPath hg38 (UCSC)WDR5B  -     chr3:122411853-122416035 -  3q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WDR5B  -     3q21.1   [Description]    (hg19-Feb_2009)
EnsemblWDR5B - 3q21.1 [CytoView hg19]  WDR5B - 3q21.1 [CytoView hg38]
Mapping of homologs : NCBIWDR5B [Mapview hg19]  WDR5B [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA310178 AA587370 AK002149 AK315186 BC025762
RefSeq transcript (Entrez)NM_019069
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)WDR5B
Cluster EST : UnigeneHs.594258 [ NCBI ]
CGAP (NCI)Hs.594258
Alternative Splicing GalleryENSG00000196981
Gene ExpressionWDR5B [ NCBI-GEO ]   WDR5B [ EBI - ARRAY_EXPRESS ]   WDR5B [ SEEK ]   WDR5B [ MEM ]
Gene Expression Viewer (FireBrowse)WDR5B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54554
GTEX Portal (Tissue expression)WDR5B
Human Protein AtlasENSG00000196981-WDR5B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86VZ2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86VZ2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86VZ2
Splice isoforms : SwissVarQ86VZ2
PhosPhoSitePlusQ86VZ2
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)G-protein_beta_WD-40_rep    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)WDR5B
DMDM Disease mutations54554
Blocks (Seattle)WDR5B
SuperfamilyQ86VZ2
Human Protein Atlas [tissue]ENSG00000196981-WDR5B [tissue]
Peptide AtlasQ86VZ2
HPRD18302
IPIIPI00329028   
Protein Interaction databases
DIP (DOE-UCLA)Q86VZ2
IntAct (EBI)Q86VZ2
FunCoupENSG00000196981
BioGRIDWDR5B
STRING (EMBL)WDR5B
ZODIACWDR5B
Ontologies - Pathways
QuickGOQ86VZ2
Ontology : AmiGOciliary basal body  cilium assembly  
Ontology : EGO-EBIciliary basal body  cilium assembly  
NDEx NetworkWDR5B
Atlas of Cancer Signalling NetworkWDR5B
Wikipedia pathwaysWDR5B
Orthology - Evolution
OrthoDB54554
GeneTree (enSembl)ENSG00000196981
Phylogenetic Trees/Animal Genes : TreeFamWDR5B
HOVERGENQ86VZ2
HOGENOMQ86VZ2
Homologs : HomoloGeneWDR5B
Homology/Alignments : Family Browser (UCSC)WDR5B
Gene fusions - Rearrangements
Fusion: Tumor Portal WDR5B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWDR5B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WDR5B
dbVarWDR5B
ClinVarWDR5B
1000_GenomesWDR5B 
Exome Variant ServerWDR5B
ExAC (Exome Aggregation Consortium)ENSG00000196981
GNOMAD BrowserENSG00000196981
Genetic variants : HAPMAP54554
Genomic Variants (DGV)WDR5B [DGVbeta]
DECIPHERWDR5B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWDR5B 
Mutations
ICGC Data PortalWDR5B 
TCGA Data PortalWDR5B 
Broad Tumor PortalWDR5B
OASIS PortalWDR5B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWDR5B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDWDR5B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WDR5B
DgiDB (Drug Gene Interaction Database)WDR5B
DoCM (Curated mutations)WDR5B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WDR5B (select a term)
intoGenWDR5B
Cancer3DWDR5B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenWDR5B
Genetic Testing Registry WDR5B
NextProtQ86VZ2 [Medical]
TSGene54554
GENETestsWDR5B
Target ValidationWDR5B
Huge Navigator WDR5B [HugePedia]
snp3D : Map Gene to Disease54554
BioCentury BCIQWDR5B
ClinGenWDR5B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54554
Chemical/Pharm GKB GenePA38248
Clinical trialWDR5B
Miscellaneous
canSAR (ICR)WDR5B (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWDR5B
EVEXWDR5B
GoPubMedWDR5B
iHOPWDR5B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:35:46 CET 2017

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