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WDR60 (WD repeat domain 60)

Identity

Alias_symbol (synonym)FLJ10300
FAP163
Other aliasSRPS6
SRTD8
HGNC (Hugo) WDR60
LocusID (NCBI) 55112
Atlas_Id 54778
Location 7q36.3  [Link to chromosome band 7q36]
Location_base_pair Starts at 158856578 and ends at 158946192 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AGK (7q34) / WDR60 (7q36.3)EVC (4p16.2) / WDR60 (7q36.3)RGS21 (1q31.2) / WDR60 (7q36.3)
WDR60 (7q36.3) / ARHGEF7 (13q34)WDR60 (7q36.3) / MYH9 (22q12.3)WDR60 (7q36.3) / RASAL2 (1q25.2)
WDR60 (7q36.3) / VIPR2 (7q36.3)WDR60 (7q36.3) / WDR60 (7q36.3)EVC 4p16.2 / WDR60 7q36.3
WDR60 7q36.3 / VIPR2 7q36.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WDR60   21862
Cards
Entrez_Gene (NCBI)WDR60  55112  WD repeat domain 60
AliasesFAP163; SRPS6; SRTD8
GeneCards (Weizmann)WDR60
Ensembl hg19 (Hinxton)ENSG00000126870 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000126870 [Gene_View]  chr7:158856578-158946192 [Contig_View]  WDR60 [Vega]
ICGC DataPortalENSG00000126870
TCGA cBioPortalWDR60
AceView (NCBI)WDR60
Genatlas (Paris)WDR60
WikiGenes55112
SOURCE (Princeton)WDR60
Genetics Home Reference (NIH)WDR60
Genomic and cartography
GoldenPath hg38 (UCSC)WDR60  -     chr7:158856578-158946192 +  7q36.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WDR60  -     7q36.3   [Description]    (hg19-Feb_2009)
EnsemblWDR60 - 7q36.3 [CytoView hg19]  WDR60 - 7q36.3 [CytoView hg38]
Mapping of homologs : NCBIWDR60 [Mapview hg19]  WDR60 [Mapview hg38]
OMIM615462   615503   
Gene and transcription
Genbank (Entrez)AK001162 AK027228 AL137660 BC014491 BM718580
RefSeq transcript (Entrez)NM_001350914 NM_001350915 NM_001350916 NM_001350917 NM_001350918 NM_018051
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)WDR60
Cluster EST : UnigeneHs.389945 [ NCBI ]
CGAP (NCI)Hs.389945
Alternative Splicing GalleryENSG00000126870
Gene ExpressionWDR60 [ NCBI-GEO ]   WDR60 [ EBI - ARRAY_EXPRESS ]   WDR60 [ SEEK ]   WDR60 [ MEM ]
Gene Expression Viewer (FireBrowse)WDR60 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55112
GTEX Portal (Tissue expression)WDR60
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WVS4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WVS4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WVS4
Splice isoforms : SwissVarQ8WVS4
PhosPhoSitePlusQ8WVS4
Domains : Interpro (EBI)WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)WDR60
DMDM Disease mutations55112
Blocks (Seattle)WDR60
SuperfamilyQ8WVS4
Human Protein AtlasENSG00000126870
Peptide AtlasQ8WVS4
HPRD08545
IPIIPI00165454   IPI00465018   IPI00894339   IPI00894550   IPI00894157   
Protein Interaction databases
DIP (DOE-UCLA)Q8WVS4
IntAct (EBI)Q8WVS4
FunCoupENSG00000126870
BioGRIDWDR60
STRING (EMBL)WDR60
ZODIACWDR60
Ontologies - Pathways
QuickGOQ8WVS4
Ontology : AmiGOpericentriolar material  spindle pole  protein binding  extracellular space  centrosome  cytoplasmic dynein complex  cilium  interphase microtubule organizing center  intraciliary transport involved in cilium assembly  dynein light chain binding  embryonic skeletal system morphogenesis  cilium assembly  cilium assembly  extracellular exosome  ciliary tip  ciliary base  ciliary base  
Ontology : EGO-EBIpericentriolar material  spindle pole  protein binding  extracellular space  centrosome  cytoplasmic dynein complex  cilium  interphase microtubule organizing center  intraciliary transport involved in cilium assembly  dynein light chain binding  embryonic skeletal system morphogenesis  cilium assembly  cilium assembly  extracellular exosome  ciliary tip  ciliary base  ciliary base  
NDEx NetworkWDR60
Atlas of Cancer Signalling NetworkWDR60
Wikipedia pathwaysWDR60
Orthology - Evolution
OrthoDB55112
GeneTree (enSembl)ENSG00000126870
Phylogenetic Trees/Animal Genes : TreeFamWDR60
HOVERGENQ8WVS4
HOGENOMQ8WVS4
Homologs : HomoloGeneWDR60
Homology/Alignments : Family Browser (UCSC)WDR60
Gene fusions - Rearrangements
Fusion : MitelmanAGK/WDR60 [7q34/7q36.3]  [t(7;7)(q34;q36)]  
Fusion : MitelmanEVC/WDR60 [4p16.2/7q36.3]  [t(4;7)(p16;q36)]  
Fusion : MitelmanWDR60/VIPR2 [7q36.3/7q36.3]  [t(7;7)(q36;q36)]  
Fusion: TCGAEVC 4p16.2 WDR60 7q36.3 BRCA
Fusion: TCGAWDR60 7q36.3 VIPR2 7q36.3 KIRC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWDR60 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WDR60
dbVarWDR60
ClinVarWDR60
1000_GenomesWDR60 
Exome Variant ServerWDR60
ExAC (Exome Aggregation Consortium)WDR60 (select the gene name)
Genetic variants : HAPMAP55112
Genomic Variants (DGV)WDR60 [DGVbeta]
DECIPHERWDR60 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWDR60 
Mutations
ICGC Data PortalWDR60 
TCGA Data PortalWDR60 
Broad Tumor PortalWDR60
OASIS PortalWDR60 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWDR60  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDWDR60
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WDR60
DgiDB (Drug Gene Interaction Database)WDR60
DoCM (Curated mutations)WDR60 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WDR60 (select a term)
intoGenWDR60
Cancer3DWDR60(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615462    615503   
Orphanet283    12214   
MedgenWDR60
Genetic Testing Registry WDR60
NextProtQ8WVS4 [Medical]
TSGene55112
GENETestsWDR60
Target ValidationWDR60
Huge Navigator WDR60 [HugePedia]
snp3D : Map Gene to Disease55112
BioCentury BCIQWDR60
ClinGenWDR60
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55112
Chemical/Pharm GKB GenePA142670594
Clinical trialWDR60
Miscellaneous
canSAR (ICR)WDR60 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWDR60
EVEXWDR60
GoPubMedWDR60
iHOPWDR60
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 13:02:48 CEST 2017

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