Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

WDR61 (WD repeat domain 61)

Identity

Alias_symbol (synonym)REC14
Other aliasSKI8
HGNC (Hugo) WDR61
LocusID (NCBI) 80349
Atlas_Id 75724
Location 15q25.1  [Link to chromosome band 15q25]
Location_base_pair Starts at 78575578 and ends at 78592068 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
EEA1 (12q22) / WDR61 (15q25.1)METAP2 (12q22) / WDR61 (15q25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WDR61   30300
Cards
Entrez_Gene (NCBI)WDR61  80349  WD repeat domain 61
AliasesREC14; SKI8
GeneCards (Weizmann)WDR61
Ensembl hg19 (Hinxton)ENSG00000140395 [Gene_View]  chr15:78575578-78592068 [Contig_View]  WDR61 [Vega]
Ensembl hg38 (Hinxton)ENSG00000140395 [Gene_View]  chr15:78575578-78592068 [Contig_View]  WDR61 [Vega]
ICGC DataPortalENSG00000140395
TCGA cBioPortalWDR61
AceView (NCBI)WDR61
Genatlas (Paris)WDR61
WikiGenes80349
SOURCE (Princeton)WDR61
Genetics Home Reference (NIH)WDR61
Genomic and cartography
GoldenPath hg19 (UCSC)WDR61  -     chr15:78575578-78592068 -  15q25.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)WDR61  -     15q25.1   [Description]    (hg38-Dec_2013)
EnsemblWDR61 - 15q25.1 [CytoView hg19]  WDR61 - 15q25.1 [CytoView hg38]
Mapping of homologs : NCBIWDR61 [Mapview hg19]  WDR61 [Mapview hg38]
OMIM609540   
Gene and transcription
Genbank (Entrez)AF100786 AF127799 AF309553 AK024754 AK025098
RefSeq transcript (Entrez)NM_001303247 NM_001303248 NM_025234
RefSeq genomic (Entrez)NC_000015 NC_018926 NT_010194 NW_004929398
Consensus coding sequences : CCDS (NCBI)WDR61
Cluster EST : UnigeneHs.513055 [ NCBI ]
CGAP (NCI)Hs.513055
Alternative Splicing GalleryENSG00000140395
Gene ExpressionWDR61 [ NCBI-GEO ]   WDR61 [ EBI - ARRAY_EXPRESS ]   WDR61 [ SEEK ]   WDR61 [ MEM ]
Gene Expression Viewer (FireBrowse)WDR61 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80349
GTEX Portal (Tissue expression)WDR61
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9GZS3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9GZS3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9GZS3
Splice isoforms : SwissVarQ9GZS3
PhosPhoSitePlusQ9GZS3
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)G-protein_beta_WD-40_rep    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)WDR61
DMDM Disease mutations80349
Blocks (Seattle)WDR61
PDB (SRS)3OW8   
PDB (PDBSum)3OW8   
PDB (IMB)3OW8   
PDB (RSDB)3OW8   
Structural Biology KnowledgeBase3OW8   
SCOP (Structural Classification of Proteins)3OW8   
CATH (Classification of proteins structures)3OW8   
SuperfamilyQ9GZS3
Human Protein AtlasENSG00000140395
Peptide AtlasQ9GZS3
HPRD15236
IPIIPI00019269   
Protein Interaction databases
DIP (DOE-UCLA)Q9GZS3
IntAct (EBI)Q9GZS3
FunCoupENSG00000140395
BioGRIDWDR61
STRING (EMBL)WDR61
ZODIACWDR61
Ontologies - Pathways
QuickGOQ9GZS3
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  cytoplasm  transcription, DNA-templated  Wnt signaling pathway  Cdc73/Paf1 complex  positive regulation of transcription elongation from RNA polymerase II promoter  nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'  transcriptionally active chromatin  negative regulation of myeloid cell differentiation  positive regulation of transcription from RNA polymerase II promoter  positive regulation of histone H3-K4 methylation  Ski complex  histone H3-K4 trimethylation  positive regulation of histone H3-K79 methylation  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  cytoplasm  transcription, DNA-templated  Wnt signaling pathway  Cdc73/Paf1 complex  positive regulation of transcription elongation from RNA polymerase II promoter  nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'  transcriptionally active chromatin  negative regulation of myeloid cell differentiation  positive regulation of transcription from RNA polymerase II promoter  positive regulation of histone H3-K4 methylation  Ski complex  histone H3-K4 trimethylation  positive regulation of histone H3-K79 methylation  
Pathways : KEGGRNA degradation   
NDEx NetworkWDR61
Atlas of Cancer Signalling NetworkWDR61
Wikipedia pathwaysWDR61
Orthology - Evolution
OrthoDB80349
GeneTree (enSembl)ENSG00000140395
Phylogenetic Trees/Animal Genes : TreeFamWDR61
HOVERGENQ9GZS3
HOGENOMQ9GZS3
Homologs : HomoloGeneWDR61
Homology/Alignments : Family Browser (UCSC)WDR61
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWDR61 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WDR61
dbVarWDR61
ClinVarWDR61
1000_GenomesWDR61 
Exome Variant ServerWDR61
ExAC (Exome Aggregation Consortium)WDR61 (select the gene name)
Genetic variants : HAPMAP80349
Genomic Variants (DGV)WDR61 [DGVbeta]
DECIPHER (Syndromes)15:78575578-78592068  ENSG00000140395
CONAN: Copy Number AnalysisWDR61 
Mutations
ICGC Data PortalWDR61 
TCGA Data PortalWDR61 
Broad Tumor PortalWDR61
OASIS PortalWDR61 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWDR61  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDWDR61
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WDR61
DgiDB (Drug Gene Interaction Database)WDR61
DoCM (Curated mutations)WDR61 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WDR61 (select a term)
intoGenWDR61
Cancer3DWDR61(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609540   
Orphanet
MedgenWDR61
Genetic Testing Registry WDR61
NextProtQ9GZS3 [Medical]
TSGene80349
GENETestsWDR61
Huge Navigator WDR61 [HugePedia]
snp3D : Map Gene to Disease80349
BioCentury BCIQWDR61
ClinGenWDR61
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80349
Chemical/Pharm GKB GenePA142670595
Clinical trialWDR61
Miscellaneous
canSAR (ICR)WDR61 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWDR61
EVEXWDR61
GoPubMedWDR61
iHOPWDR61
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:51:37 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.