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WDR70 (WD repeat domain 70)

Identity

Alias_symbol (synonym)FLJ10233
Other alias-
HGNC (Hugo) WDR70
LocusID (NCBI) 55100
Atlas_Id 54779
Location 5p13.2  [Link to chromosome band 5p13]
Location_base_pair Starts at 37379412 and ends at 37752774 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
AP1G1 (16q22.2) / WDR70 (5p13.2)APOBEC3F (22q13.1) / WDR70 (5p13.2)RCOR1 (14q32.31) / WDR70 (5p13.2)
WDR26 (1q42.11) / WDR70 (5p13.2)WDR70 (5p13.2) / ADAMTS12 (5p13.3)WDR70 (5p13.2) / C10orf25 (10q11.21)
WDR70 (5p13.2) / CACNA2D4 (12p13.33)WDR70 (5p13.2) / DDX17 (22q13.1)WDR70 (5p13.2) / EIF2S3 (Xp22.11)
WDR70 (5p13.2) / MALAT1 (11q13.1)WDR70 (5p13.2) / PGAP3 (17q12)WDR70 (5p13.2) / PLCXD3 (5p13.1)
WDR70 5p13.2 / ADAMTS12 5p13.3WDR70 5p13.2 / C10orf25 10q11.21WDR70 5p13.2 / CACNA2D4 12p13.33
WDR70 5p13.2 / PGAP3 17q12WDR70 5p13.2 / PLCXD3 5p13.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WDR70   25495
Cards
Entrez_Gene (NCBI)WDR70  55100  WD repeat domain 70
Aliases
GeneCards (Weizmann)WDR70
Ensembl hg19 (Hinxton)ENSG00000082068 [Gene_View]  chr5:37379412-37752774 [Contig_View]  WDR70 [Vega]
Ensembl hg38 (Hinxton)ENSG00000082068 [Gene_View]  chr5:37379412-37752774 [Contig_View]  WDR70 [Vega]
ICGC DataPortalENSG00000082068
TCGA cBioPortalWDR70
AceView (NCBI)WDR70
Genatlas (Paris)WDR70
WikiGenes55100
SOURCE (Princeton)WDR70
Genetics Home Reference (NIH)WDR70
Genomic and cartography
GoldenPath hg19 (UCSC)WDR70  -     chr5:37379412-37752774 +  5p13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)WDR70  -     5p13.2   [Description]    (hg38-Dec_2013)
EnsemblWDR70 - 5p13.2 [CytoView hg19]  WDR70 - 5p13.2 [CytoView hg38]
Mapping of homologs : NCBIWDR70 [Mapview hg19]  WDR70 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK001095 AK291179 AK310901 AL512685 BC009648
RefSeq transcript (Entrez)NM_018034
RefSeq genomic (Entrez)NC_000005 NC_018916 NT_006576 NW_004929321
Consensus coding sequences : CCDS (NCBI)WDR70
Cluster EST : UnigeneHs.213690 [ NCBI ]
CGAP (NCI)Hs.213690
Alternative Splicing GalleryENSG00000082068
Gene ExpressionWDR70 [ NCBI-GEO ]   WDR70 [ EBI - ARRAY_EXPRESS ]   WDR70 [ SEEK ]   WDR70 [ MEM ]
Gene Expression Viewer (FireBrowse)WDR70 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55100
GTEX Portal (Tissue expression)WDR70
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NW82   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NW82  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NW82
Splice isoforms : SwissVarQ9NW82
PhosPhoSitePlusQ9NW82
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)WDR70
DMDM Disease mutations55100
Blocks (Seattle)WDR70
SuperfamilyQ9NW82
Human Protein AtlasENSG00000082068
Peptide AtlasQ9NW82
HPRD08542
IPIIPI00300060   IPI00965966   
Protein Interaction databases
DIP (DOE-UCLA)Q9NW82
IntAct (EBI)Q9NW82
FunCoupENSG00000082068
BioGRIDWDR70
STRING (EMBL)WDR70
ZODIACWDR70
Ontologies - Pathways
QuickGOQ9NW82
Ontology : AmiGOenzyme binding  
Ontology : EGO-EBIenzyme binding  
NDEx NetworkWDR70
Atlas of Cancer Signalling NetworkWDR70
Wikipedia pathwaysWDR70
Orthology - Evolution
OrthoDB55100
GeneTree (enSembl)ENSG00000082068
Phylogenetic Trees/Animal Genes : TreeFamWDR70
HOVERGENQ9NW82
HOGENOMQ9NW82
Homologs : HomoloGeneWDR70
Homology/Alignments : Family Browser (UCSC)WDR70
Gene fusions - Rearrangements
Fusion : MitelmanRCOR1/WDR70 [14q32.31/5p13.2]  [t(5;14)(p13;q32)]  
Fusion : MitelmanWDR70/ADAMTS12 [5p13.2/5p13.3]  [t(5;5)(p13;p13)]  
Fusion : MitelmanWDR70/C10orf25 [5p13.2/10q11.21]  [t(5;10)(p13;q11)]  
Fusion : MitelmanWDR70/CACNA2D4 [5p13.2/12p13.33]  [t(5;12)(p13;p13)]  
Fusion : MitelmanWDR70/PGAP3 [5p13.2/17q12]  [t(5;17)(p13;q12)]  
Fusion : MitelmanWDR70/PLCXD3 [5p13.2/5p13.1]  [t(5;5)(p13;p13)]  
Fusion: TCGAWDR70 5p13.2 ADAMTS12 5p13.3 BRCA
Fusion: TCGAWDR70 5p13.2 C10orf25 10q11.21 BRCA
Fusion: TCGAWDR70 5p13.2 CACNA2D4 12p13.33 BLCA
Fusion: TCGAWDR70 5p13.2 PGAP3 17q12 BRCA
Fusion: TCGAWDR70 5p13.2 PLCXD3 5p13.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWDR70 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WDR70
dbVarWDR70
ClinVarWDR70
1000_GenomesWDR70 
Exome Variant ServerWDR70
ExAC (Exome Aggregation Consortium)WDR70 (select the gene name)
Genetic variants : HAPMAP55100
Genomic Variants (DGV)WDR70 [DGVbeta]
DECIPHER (Syndromes)5:37379412-37752774  ENSG00000082068
CONAN: Copy Number AnalysisWDR70 
Mutations
ICGC Data PortalWDR70 
TCGA Data PortalWDR70 
Broad Tumor PortalWDR70
OASIS PortalWDR70 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWDR70  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDWDR70
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WDR70
DgiDB (Drug Gene Interaction Database)WDR70
DoCM (Curated mutations)WDR70 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WDR70 (select a term)
intoGenWDR70
Cancer3DWDR70(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenWDR70
Genetic Testing Registry WDR70
NextProtQ9NW82 [Medical]
TSGene55100
GENETestsWDR70
Huge Navigator WDR70 [HugePedia]
snp3D : Map Gene to Disease55100
BioCentury BCIQWDR70
ClinGenWDR70
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55100
Chemical/Pharm GKB GenePA142670603
Clinical trialWDR70
Miscellaneous
canSAR (ICR)WDR70 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWDR70
EVEXWDR70
GoPubMedWDR70
iHOPWDR70
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:34:11 CET 2017

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