WDR76 (WD repeat domain 76)

2007-02-01  

Identity

HGNC
LOCATION
15q15.3
LOCUSID
ALIAS
CDW14
FUSION GENES

Other Information

Locus ID:

NCBI: 79968
HGNC: 25773
Ensembl: ENSG00000092470

Variants:

dbSNP: 79968
ClinVar: 79968
TCGA: ENSG00000092470
COSMIC: WDR76

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000092470ENST00000263795Q9H967
ENSG00000092470ENST00000381246A0A0C4DFX7
ENSG00000092470ENST00000452115C9JE56

Expression (GTEx)

0
5
10
15
20
25
30

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
353812632022Kurarinone induced p53-independent G0/G1 cell cycle arrest by degradation of K-RAS via WDR76 in human colorectal cancer cells.3
353812632022Kurarinone induced p53-independent G0/G1 cell cycle arrest by degradation of K-RAS via WDR76 in human colorectal cancer cells.3
337142592021The role of WDR76 protein in human diseases.4
337142592021The role of WDR76 protein in human diseases.4
306556112019WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation.16
313539122019Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.10
313627612019WDR76 degrades RAS and suppresses cancer stem cell activation in colorectal cancer.11
306556112019WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation.16
313539122019Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.10
313627612019WDR76 degrades RAS and suppresses cancer stem cell activation in colorectal cancer.11
272484962016WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.16
272484962016WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.16
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105

Citation

Dessen P

WDR76 (WD repeat domain 76)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45581/wdr76