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WDR81 (WD repeat domain 81)

Identity

Alias (NCBI)CAMRQ2
HYC3
PPP1R166
SORF-2
HGNC (Hugo) WDR81
HGNC Alias symbFLJ33817
PPP1R166
CAMRQ2
SORF-2
HGNC Alias nameprotein phosphatase 1, regulatory subunit 166
LocusID (NCBI) 124997
Atlas_Id 57243
Location 17p13.3  [Link to chromosome band 17p13]
Location_base_pair Starts at 1716523 and ends at 1738585 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WDR81   26600
Cards
Entrez_Gene (NCBI)WDR81  124997  WD repeat domain 81
AliasesCAMRQ2; HYC3; PPP1R166; SORF-2
GeneCards (Weizmann)WDR81
Ensembl hg19 (Hinxton)ENSG00000167716 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167716 [Gene_View]  ENSG00000167716 [Sequence]  chr17:1716523-1738585 [Contig_View]  WDR81 [Vega]
ICGC DataPortalENSG00000167716
TCGA cBioPortalWDR81
AceView (NCBI)WDR81
Genatlas (Paris)WDR81
WikiGenes124997
SOURCE (Princeton)WDR81
Genetics Home Reference (NIH)WDR81
Genomic and cartography
GoldenPath hg38 (UCSC)WDR81  -     chr17:1716523-1738585 +  17p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WDR81  -     17p13.3   [Description]    (hg19-Feb_2009)
GoldenPathWDR81 - 17p13.3 [CytoView hg19]  WDR81 - 17p13.3 [CytoView hg38]
ImmunoBaseENSG00000167716
genome Data Viewer NCBIWDR81 [Mapview hg19]  
OMIM610185   614218   617967   
Gene and transcription
Genbank (Entrez)AI168277 AI916244 AK074111 AK074356 AK091136
RefSeq transcript (Entrez)NM_001163673 NM_001163809 NM_001163811 NM_152348
RefSeq genomic (Entrez)NC_000017 NG_032811 NT_187611
Consensus coding sequences : CCDS (NCBI)WDR81
Alternative Splicing GalleryENSG00000167716
Gene ExpressionWDR81 [ NCBI-GEO ]   WDR81 [ EBI - ARRAY_EXPRESS ]   WDR81 [ SEEK ]   WDR81 [ MEM ]
Gene Expression Viewer (FireBrowse)WDR81 [ Firebrowse - Broad ]
GenevisibleExpression of WDR81 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)124997
GTEX Portal (Tissue expression)WDR81
Human Protein AtlasENSG00000167716-WDR81 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ562E7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ562E7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ562E7
Splice isoforms : SwissVarQ562E7
PhosPhoSitePlusQ562E7
Domaine pattern : Prosite (Expaxy)BEACH (PS50197)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)BEACH_dom    BEACH_dom_sf    Kinase-like_dom_sf    WD40/YVTN_repeat-like_dom_sf    WD40_repeat    WD40_repeat_dom    WD40_repeat_dom_sf   
Domain families : Pfam (Sanger)Beach (PF02138)    WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam02138    pfam00400   
Domain families : Smart (EMBL)Beach (SM01026)  WD40 (SM00320)  
Conserved Domain (NCBI)WDR81
DMDM Disease mutations124997
Blocks (Seattle)WDR81
SuperfamilyQ562E7
Human Protein Atlas [tissue]ENSG00000167716-WDR81 [tissue]
Peptide AtlasQ562E7
IPIIPI00943756   IPI00784299   IPI00924963   IPI00927804   IPI00917671   IPI00926441   IPI01009619   
Protein Interaction databases
DIP (DOE-UCLA)Q562E7
IntAct (EBI)Q562E7
FunCoupENSG00000167716
BioGRIDWDR81
STRING (EMBL)WDR81
ZODIACWDR81
Ontologies - Pathways
QuickGOQ562E7
Ontology : AmiGOautophagosome membrane  protein binding  mitochondrion  lysosomal membrane  endoplasmic reticulum membrane  Golgi apparatus  cytosol  ubiquitin-dependent protein catabolic process  mitochondrion organization  negative regulation of phosphatase activity  extrinsic component of endosome membrane  early endosome membrane  late endosome membrane  phosphatidylinositol 3-kinase regulator activity  aggrephagy  regulation of phosphatidylinositol 3-kinase activity  early endosome to late endosome transport  protein stabilization  K63-linked polyubiquitin modification-dependent protein binding  
Ontology : EGO-EBIautophagosome membrane  protein binding  mitochondrion  lysosomal membrane  endoplasmic reticulum membrane  Golgi apparatus  cytosol  ubiquitin-dependent protein catabolic process  mitochondrion organization  negative regulation of phosphatase activity  extrinsic component of endosome membrane  early endosome membrane  late endosome membrane  phosphatidylinositol 3-kinase regulator activity  aggrephagy  regulation of phosphatidylinositol 3-kinase activity  early endosome to late endosome transport  protein stabilization  K63-linked polyubiquitin modification-dependent protein binding  
NDEx NetworkWDR81
Atlas of Cancer Signalling NetworkWDR81
Wikipedia pathwaysWDR81
Orthology - Evolution
OrthoDB124997
GeneTree (enSembl)ENSG00000167716
Phylogenetic Trees/Animal Genes : TreeFamWDR81
HOGENOMQ562E7
Homologs : HomoloGeneWDR81
Homology/Alignments : Family Browser (UCSC)WDR81
Gene fusions - Rearrangements
Fusion : QuiverWDR81
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWDR81 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WDR81
dbVarWDR81
ClinVarWDR81
1000_GenomesWDR81 
Exome Variant ServerWDR81
GNOMAD BrowserENSG00000167716
Varsome BrowserWDR81
Genetic variants : HAPMAP124997
Genomic Variants (DGV)WDR81 [DGVbeta]
DECIPHERWDR81 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWDR81 
Mutations
ICGC Data PortalWDR81 
TCGA Data PortalWDR81 
Broad Tumor PortalWDR81
OASIS PortalWDR81 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWDR81  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DWDR81
Mutations and Diseases : HGMDWDR81
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WDR81
DgiDB (Drug Gene Interaction Database)WDR81
DoCM (Curated mutations)WDR81 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WDR81 (select a term)
intoGenWDR81
Cancer3DWDR81(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610185    614218    617967   
Orphanet
DisGeNETWDR81
MedgenWDR81
Genetic Testing Registry WDR81
NextProtQ562E7 [Medical]
TSGene124997
GENETestsWDR81
Target ValidationWDR81
Huge Navigator WDR81 [HugePedia]
snp3D : Map Gene to Disease124997
BioCentury BCIQWDR81
ClinGenWDR81
Clinical trials, drugs, therapy
Protein Interactions : CTD124997
Pharm GKB GenePA142670584
Clinical trialWDR81
Miscellaneous
canSAR (ICR)WDR81 (select the gene name)
HarmonizomeWDR81
DataMed IndexWDR81
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWDR81
EVEXWDR81
GoPubMedWDR81
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jul 16 15:42:34 CEST 2020

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