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WEE2 (WEE1 homolog 2)

Identity

Alias_namesWEE1 homolog 2 (S. pombe)
Alias_symbol (synonym)FLJ16107
Other aliasWEE1B
HGNC (Hugo) WEE2
LocusID (NCBI) 494551
Atlas_Id 75745
Location 7q34  [Link to chromosome band 7q34]
Location_base_pair Starts at 141708353 and ends at 141731271 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WEE2   19684
Cards
Entrez_Gene (NCBI)WEE2  494551  WEE1 homolog 2
AliasesWEE1B
GeneCards (Weizmann)WEE2
Ensembl hg19 (Hinxton)ENSG00000214102 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000214102 [Gene_View]  chr7:141708353-141731271 [Contig_View]  WEE2 [Vega]
ICGC DataPortalENSG00000214102
TCGA cBioPortalWEE2
AceView (NCBI)WEE2
Genatlas (Paris)WEE2
WikiGenes494551
SOURCE (Princeton)WEE2
Genetics Home Reference (NIH)WEE2
Genomic and cartography
GoldenPath hg38 (UCSC)WEE2  -     chr7:141708353-141731271 +  7q34   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WEE2  -     7q34   [Description]    (hg19-Feb_2009)
EnsemblWEE2 - 7q34 [CytoView hg19]  WEE2 - 7q34 [CytoView hg38]
Mapping of homologs : NCBIWEE2 [Mapview hg19]  WEE2 [Mapview hg38]
OMIM614084   
Gene and transcription
Genbank (Entrez)AK131218 BC172300 BG402079 BM790836
RefSeq transcript (Entrez)NM_001105558
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)WEE2
Cluster EST : UnigeneHs.657927 [ NCBI ]
CGAP (NCI)Hs.657927
Alternative Splicing GalleryENSG00000214102
Gene ExpressionWEE2 [ NCBI-GEO ]   WEE2 [ EBI - ARRAY_EXPRESS ]   WEE2 [ SEEK ]   WEE2 [ MEM ]
Gene Expression Viewer (FireBrowse)WEE2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]     [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)494551
GTEX Portal (Tissue expression)WEE2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP0C1S8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP0C1S8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP0C1S8
Splice isoforms : SwissVarP0C1S8
Catalytic activity : Enzyme2.7.10.2 [ Enzyme-Expasy ]   2.7.10.22.7.10.2 [ IntEnz-EBI ]   2.7.10.2 [ BRENDA ]   2.7.10.2 [ KEGG ]   
PhosPhoSitePlusP0C1S8
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_kinase_AS    Wee1-like_protein_kinase   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
Conserved Domain (NCBI)WEE2
DMDM Disease mutations494551
Blocks (Seattle)WEE2
SuperfamilyP0C1S8
Human Protein AtlasENSG00000214102
Peptide AtlasP0C1S8
IPIIPI00745231   IPI00947439   
Protein Interaction databases
DIP (DOE-UCLA)P0C1S8
IntAct (EBI)P0C1S8
FunCoupENSG00000214102
BioGRIDWEE2
STRING (EMBL)WEE2
ZODIACWEE2
Ontologies - Pathways
QuickGOP0C1S8
Ontology : AmiGOmagnesium ion binding  non-membrane spanning protein tyrosine kinase activity  ATP binding  nucleoplasm  cytosol  female meiotic nuclear division  peptidyl-tyrosine phosphorylation  female pronucleus assembly  negative regulation of cyclin-dependent protein serine/threonine kinase activity  regulation of meiosis I  negative regulation of oocyte maturation  
Ontology : EGO-EBImagnesium ion binding  non-membrane spanning protein tyrosine kinase activity  ATP binding  nucleoplasm  cytosol  female meiotic nuclear division  peptidyl-tyrosine phosphorylation  female pronucleus assembly  negative regulation of cyclin-dependent protein serine/threonine kinase activity  regulation of meiosis I  negative regulation of oocyte maturation  
Pathways : KEGGCell cycle   
NDEx NetworkWEE2
Atlas of Cancer Signalling NetworkWEE2
Wikipedia pathwaysWEE2
Orthology - Evolution
OrthoDB494551
GeneTree (enSembl)ENSG00000214102
Phylogenetic Trees/Animal Genes : TreeFamWEE2
HOVERGENP0C1S8
HOGENOMP0C1S8
Homologs : HomoloGeneWEE2
Homology/Alignments : Family Browser (UCSC)WEE2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWEE2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WEE2
dbVarWEE2
ClinVarWEE2
1000_GenomesWEE2 
Exome Variant ServerWEE2
ExAC (Exome Aggregation Consortium)WEE2 (select the gene name)
Genetic variants : HAPMAP494551
Genomic Variants (DGV)WEE2 [DGVbeta]
DECIPHERWEE2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWEE2 
Mutations
ICGC Data PortalWEE2 
TCGA Data PortalWEE2 
Broad Tumor PortalWEE2
OASIS PortalWEE2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWEE2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDWEE2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WEE2
DgiDB (Drug Gene Interaction Database)WEE2
DoCM (Curated mutations)WEE2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WEE2 (select a term)
intoGenWEE2
Cancer3DWEE2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614084   
Orphanet
MedgenWEE2
Genetic Testing Registry WEE2
NextProtP0C1S8 [Medical]
TSGene494551
GENETestsWEE2
Target ValidationWEE2
Huge Navigator WEE2 [HugePedia]
snp3D : Map Gene to Disease494551
BioCentury BCIQWEE2
ClinGenWEE2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD494551
Chemical/Pharm GKB GenePA134909633
Clinical trialWEE2
Miscellaneous
canSAR (ICR)WEE2 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWEE2
EVEXWEE2
GoPubMedWEE2
iHOPWEE2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:43:51 CEST 2017

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