Atlas of Genetics and Cytogenetics in Oncology and Haematology

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WFDC2 (WAP four-disulfide core domain 2)

Identity

Other namesEDDM4
HE4
WAP5
dJ461P17.6
HGNC (Hugo) WFDC2
LocusID (NCBI) 10406
Location 20q13.12
Location_base_pair Starts at 44098394 and ends at 44110172 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)WFDC2   15939
Cards
Entrez_Gene (NCBI)WFDC2  10406  WAP four-disulfide core domain 2
GeneCards (Weizmann)WFDC2
Ensembl hg19 (Hinxton)ENSG00000101443 [Gene_View]  chr20:44098394-44110172 [Contig_View]  WFDC2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000101443 [Gene_View]  chr20:44098394-44110172 [Contig_View]  WFDC2 [Vega]
ICGC DataPortalENSG00000101443
cBioPortalWFDC2
AceView (NCBI)WFDC2
Genatlas (Paris)WFDC2
WikiGenes10406
SOURCE (Princeton)WFDC2
Genomic and cartography
GoldenPath hg19 (UCSC)WFDC2  -     chr20:44098394-44110172 +  20q13.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)WFDC2  -     20q13.12   [Description]    (hg38-Dec_2013)
EnsemblWFDC2 - 20q13.12 [CytoView hg19]  WFDC2 - 20q13.12 [CytoView hg38]
Mapping of homologs : NCBIWFDC2 [Mapview hg19]  WFDC2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF330259 AF330260 AF330261 AF330262 AK225528
RefSeq transcript (Entrez)NM_006103 NM_080733 NM_080734 NM_080735 NM_080736
RefSeq genomic (Entrez)AC_000152 NC_000020 NC_018931 NT_011362 NW_001838666 NW_004929418
Consensus coding sequences : CCDS (NCBI)WFDC2
Cluster EST : UnigeneHs.2719 [ NCBI ]
CGAP (NCI)Hs.2719
Alternative Splicing : Fast-db (Paris)GSHG0018784
Alternative Splicing GalleryENSG00000101443
Gene ExpressionWFDC2 [ NCBI-GEO ]     WFDC2 [ SEEK ]   WFDC2 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14508 (Uniprot)
NextProtQ14508  [Medical]
With graphics : InterProQ14508
Splice isoforms : SwissVarQ14508 (Swissvar)
Domaine pattern : Prosite (Expaxy)WAP (PS51390)   
Domains : Interpro (EBI)WAP-type_4-diS_core   
Related proteins : CluSTrQ14508
Domain families : Pfam (Sanger)WAP (PF00095)   
Domain families : Pfam (NCBI)pfam00095   
Domain families : Smart (EMBL)WAP (SM00217)  
DMDM Disease mutations10406
Blocks (Seattle)Q14508
Human Protein AtlasENSG00000101443
Peptide AtlasQ14508
HPRD11684
IPIIPI00291488   IPI00103636   IPI00183629   IPI00103639   IPI00103633   IPI00853597   
Protein Interaction databases
DIP (DOE-UCLA)Q14508
IntAct (EBI)Q14508
FunCoupENSG00000101443
BioGRIDWFDC2
IntegromeDBWFDC2
STRING (EMBL)WFDC2
Ontologies - Pathways
QuickGOQ14508
Ontology : AmiGOendopeptidase inhibitor activity  serine-type endopeptidase inhibitor activity  cysteine-type endopeptidase inhibitor activity  extracellular space  proteolysis  spermatogenesis  negative regulation of endopeptidase activity  negative regulation of endopeptidase activity  aspartic-type endopeptidase inhibitor activity  extracellular vesicular exosome  
Ontology : EGO-EBIendopeptidase inhibitor activity  serine-type endopeptidase inhibitor activity  cysteine-type endopeptidase inhibitor activity  extracellular space  proteolysis  spermatogenesis  negative regulation of endopeptidase activity  negative regulation of endopeptidase activity  aspartic-type endopeptidase inhibitor activity  extracellular vesicular exosome  
Protein Interaction DatabaseWFDC2
DoCM (Curated mutations)WFDC2
Wikipedia pathwaysWFDC2
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerWFDC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WFDC2
dbVarWFDC2
ClinVarWFDC2
1000_GenomesWFDC2 
Exome Variant ServerWFDC2
SNP (GeneSNP Utah)WFDC2
SNP : HGBaseWFDC2
Genetic variants : HAPMAPWFDC2
Genomic VariantsWFDC2  WFDC2 [DGVbeta]
Mutations
ICGC Data PortalENSG00000101443 
Somatic Mutations in Cancer : COSMICWFDC2 
CONAN: Copy Number AnalysisWFDC2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)20:44098394-44110172
Mutations and Diseases : HGMDWFDC2
OMIM
MedgenWFDC2
NextProtQ14508 [Medical]
GENETestsWFDC2
Disease Genetic AssociationWFDC2
Huge Navigator WFDC2 [HugePedia]  WFDC2 [HugeCancerGEM]
snp3D : Map Gene to Disease10406
DGIdb (Drug Gene Interaction db)WFDC2
General knowledge
Homologs : HomoloGeneWFDC2
Homology/Alignments : Family Browser (UCSC)WFDC2
Phylogenetic Trees/Animal Genes : TreeFamWFDC2
Chemical/Protein Interactions : CTD10406
Chemical/Pharm GKB GenePA38059
Clinical trialWFDC2
Cancer Resource (Charite)ENSG00000101443
Other databases
Probes
Litterature
PubMed75 Pubmed reference(s) in Entrez
CoreMineWFDC2
GoPubMedWFDC2
iHOPWFDC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Dec 21 02:18:18 CET 2014
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