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WFDC8 (WAP four-disulfide core domain 8)

Identity

Alias_namesC20orf170
chromosome 20 open reading frame 170
Alias_symbol (synonym)dJ461P17.1
WAP8
Other aliasHEL-S-292
HGNC (Hugo) WFDC8
LocusID (NCBI) 90199
Atlas_Id 75755
Location 20q13.12  [Link to chromosome band 20q13]
Location_base_pair Starts at 45551762 and ends at 45579326 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WFDC8   16163
Cards
Entrez_Gene (NCBI)WFDC8  90199  WAP four-disulfide core domain 8
AliasesC20orf170; HEL-S-292; WAP8; dJ461P17.1
GeneCards (Weizmann)WFDC8
Ensembl hg19 (Hinxton)ENSG00000158901 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000158901 [Gene_View]  chr20:45551762-45579326 [Contig_View]  WFDC8 [Vega]
ICGC DataPortalENSG00000158901
TCGA cBioPortalWFDC8
AceView (NCBI)WFDC8
Genatlas (Paris)WFDC8
WikiGenes90199
SOURCE (Princeton)WFDC8
Genetics Home Reference (NIH)WFDC8
Genomic and cartography
GoldenPath hg38 (UCSC)WFDC8  -     chr20:45551762-45579326 -  20q13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WFDC8  -     20q13.12   [Description]    (hg19-Feb_2009)
EnsemblWFDC8 - 20q13.12 [CytoView hg19]  WFDC8 - 20q13.12 [CytoView hg38]
Mapping of homologs : NCBIWFDC8 [Mapview hg19]  WFDC8 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF492015 AF492016 AL591715 BC172333 GQ472209
RefSeq transcript (Entrez)NM_130896 NM_181510
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)WFDC8
Cluster EST : UnigeneHs.116128 [ NCBI ]
CGAP (NCI)Hs.116128
Alternative Splicing GalleryENSG00000158901
Gene ExpressionWFDC8 [ NCBI-GEO ]   WFDC8 [ EBI - ARRAY_EXPRESS ]   WFDC8 [ SEEK ]   WFDC8 [ MEM ]
Gene Expression Viewer (FireBrowse)WFDC8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)90199
GTEX Portal (Tissue expression)WFDC8
Human Protein AtlasENSG00000158901-WFDC8 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IUA0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IUA0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IUA0
Splice isoforms : SwissVarQ8IUA0
PhosPhoSitePlusQ8IUA0
Domaine pattern : Prosite (Expaxy)BPTI_KUNITZ_1 (PS00280)    BPTI_KUNITZ_2 (PS50279)    WAP (PS51390)   
Domains : Interpro (EBI)Kunitz_BPTI    Prtase_inh_Kunz-CS    WAP_dom   
Domain families : Pfam (Sanger)Kunitz_BPTI (PF00014)    WAP (PF00095)   
Domain families : Pfam (NCBI)pfam00014    pfam00095   
Domain families : Smart (EMBL)KU (SM00131)  WAP (SM00217)  
Conserved Domain (NCBI)WFDC8
DMDM Disease mutations90199
Blocks (Seattle)WFDC8
SuperfamilyQ8IUA0
Human Protein Atlas [tissue]ENSG00000158901-WFDC8 [tissue]
Peptide AtlasQ8IUA0
HPRD11685
IPIIPI00216698   
Protein Interaction databases
DIP (DOE-UCLA)Q8IUA0
IntAct (EBI)Q8IUA0
FunCoupENSG00000158901
BioGRIDWFDC8
STRING (EMBL)WFDC8
ZODIACWFDC8
Ontologies - Pathways
QuickGOQ8IUA0
Ontology : AmiGOserine-type endopeptidase inhibitor activity  extracellular region  negative regulation of endopeptidase activity  
Ontology : EGO-EBIserine-type endopeptidase inhibitor activity  extracellular region  negative regulation of endopeptidase activity  
NDEx NetworkWFDC8
Atlas of Cancer Signalling NetworkWFDC8
Wikipedia pathwaysWFDC8
Orthology - Evolution
OrthoDB90199
GeneTree (enSembl)ENSG00000158901
Phylogenetic Trees/Animal Genes : TreeFamWFDC8
HOVERGENQ8IUA0
HOGENOMQ8IUA0
Homologs : HomoloGeneWFDC8
Homology/Alignments : Family Browser (UCSC)WFDC8
Gene fusions - Rearrangements
Tumor Fusion PortalWFDC8
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWFDC8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WFDC8
dbVarWFDC8
ClinVarWFDC8
1000_GenomesWFDC8 
Exome Variant ServerWFDC8
ExAC (Exome Aggregation Consortium)ENSG00000158901
GNOMAD BrowserENSG00000158901
Genetic variants : HAPMAP90199
Genomic Variants (DGV)WFDC8 [DGVbeta]
DECIPHERWFDC8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWFDC8 
Mutations
ICGC Data PortalWFDC8 
TCGA Data PortalWFDC8 
Broad Tumor PortalWFDC8
OASIS PortalWFDC8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWFDC8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDWFDC8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WFDC8
DgiDB (Drug Gene Interaction Database)WFDC8
DoCM (Curated mutations)WFDC8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WFDC8 (select a term)
intoGenWFDC8
Cancer3DWFDC8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETWFDC8
MedgenWFDC8
Genetic Testing Registry WFDC8
NextProtQ8IUA0 [Medical]
TSGene90199
GENETestsWFDC8
Target ValidationWFDC8
Huge Navigator WFDC8 [HugePedia]
snp3D : Map Gene to Disease90199
BioCentury BCIQWFDC8
ClinGenWFDC8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD90199
Chemical/Pharm GKB GenePA25713
Clinical trialWFDC8
Miscellaneous
canSAR (ICR)WFDC8 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWFDC8
EVEXWFDC8
GoPubMedWFDC8
iHOPWFDC8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Nov 20 20:21:47 CET 2017

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