WFIKKN2 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2)

2008-10-01  

Identity

HGNC
LOCATION
17q21.33
LOCUSID
ALIAS
GASP-1,WFDC20B,WFIKKNRP,hGASP-1
FUSION GENES

Other Information

Locus ID:

NCBI: 124857
MIM: 610895
HGNC: 30916
Ensembl: ENSG00000173714

Variants:

dbSNP: 124857
ClinVar: 124857
TCGA: ENSG00000173714
COSMIC: WFIKKN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173714ENST00000311378Q8TEU8
ENSG00000173714ENST00000426127C9J6G4

Expression (GTEx)

0
50
100
150
200
250

References

Pubmed IDYearTitleCitations
185960302008Both WFIKKN1 and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11.25
200263782010Effects of oral creatine and resistance training on serum myostatin and GASP-1.20
210547892010WFIKKN1 and WFIKKN2 bind growth factors TGFβ1, BMP2 and BMP4 but do not inhibit their signalling activity.15
119288172002Distinct expression pattern of two related human proteins containing multiple types of protease-inhibitory modules.12
238296722013Latent myostatin has significant activity and this activity is controlled more efficiently by WFIKKN1 than by WFIKKN2.9
280052672017Human gingiva transcriptome during wound healing.6
223952772012Hormone therapy and maximal eccentric exercise alters myostatin-related gene expression in postmenopausal women.5
273254602016WFIKKN1 and WFIKKN2: "Companion" proteins regulating TGFB activity.3

Citation

Dessen P

WFIKKN2 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2)

Atlas Genet Cytogenet Oncol Haematol. 2008-10-01

Online version: http://atlasgeneticsoncology.org/gene/50420/wfikkn2