WHAMM (WASP homolog associated with actin, golgi membranes and microtubules)

2014-11-01  

Identity

HGNC
LOCATION
15q25.2
LOCUSID
ALIAS
WHAMM1,WHDC1
FUSION GENES

Other Information

Locus ID:

NCBI: 123720
MIM: 612393
HGNC: 30493
Ensembl: ENSG00000156232

Variants:

dbSNP: 123720
ClinVar: 123720
TCGA: ENSG00000156232
COSMIC: WHAMM

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000156232ENST00000286760Q8TF30

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Tight junctionKEGGko04530
Tight junctionKEGGhsa04530

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
260969742015WHAMM Directs the Arp2/3 Complex to the ER for Autophagosome Biogenesis through an Actin Comet Tail Mechanism.33
230872062012RhoD regulates cytoskeletal dynamics via the actin nucleation-promoting factor WASp homologue associated with actin Golgi membranes and microtubules.16
230279052012Structural insights into WHAMM-mediated cytoskeletal coordination during membrane remodeling.13
314205342019WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes.1

Citation

Dessen P

WHAMM (WASP homolog associated with actin, golgi membranes and microtubules)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75759/whamm