Identity
HGNC
LOCATION
2q31.1
LOCUSID
ALIAS
PRPL-2,WAS2,WASPIP,WIP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7456
MIM: 602357
HGNC: 12736
Ensembl: ENSG00000115935
Variants:
dbSNP: 7456
ClinVar: 7456
TCGA: ENSG00000115935
COSMIC: WIPF1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 29172947 | 2020 | Crosstalk between WIP and Rho family GTPases. | 4 |
| 32147726 | 2020 | DNA Methylation-Mediated Modulation of Endocytosis as Potential Mechanism for Synaptic Function Regulation in Murine Inhibitory Cortical Interneurons. | 19 |
| 32632098 | 2020 | PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer. | 72 |
| 32708183 | 2020 | The Disordered Cellular Multi-Tasker WIP and Its Protein-Protein Interactions: A Structural View. | 5 |
| 29172947 | 2020 | Crosstalk between WIP and Rho family GTPases. | 4 |
| 32147726 | 2020 | DNA Methylation-Mediated Modulation of Endocytosis as Potential Mechanism for Synaptic Function Regulation in Murine Inhibitory Cortical Interneurons. | 19 |
| 32632098 | 2020 | PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer. | 72 |
| 32708183 | 2020 | The Disordered Cellular Multi-Tasker WIP and Its Protein-Protein Interactions: A Structural View. | 5 |
| 29215267 | 2018 | New Structural Insights into Formation of the Key Actin Regulating WIP-WASp Complex Determined by NMR and Molecular Imaging. | 4 |
| 30041660 | 2018 | WIPF1 antagonizes the tumor suppressive effect of miR-141/200c and is associated with poor survival in patients with PDAC. | 18 |
| 29215267 | 2018 | New Structural Insights into Formation of the Key Actin Regulating WIP-WASp Complex Determined by NMR and Molecular Imaging. | 4 |
| 30041660 | 2018 | WIPF1 antagonizes the tumor suppressive effect of miR-141/200c and is associated with poor survival in patients with PDAC. | 18 |
| 27742395 | 2017 | Hematopoietic stem cell transplantation corrects WIP deficiency. | 9 |
| 27863429 | 2017 | Epigenetically upregulated WIPF1 plays a major role in BRAF V600E-promoted papillary thyroid cancer aggressiveness. | 9 |
| 27939884 | 2017 | WIP promotes in-vitro invasion ability, anchorage independent growth and EMT progression of A549 lung adenocarcinoma cells by regulating RhoA levels. | 16 |
Citation
Dessen P
WIPF1 (WAS/WASL interacting protein family member 1)
Atlas Genet Cytogenet Oncol Haematol. 2009-09-01
Online version: http://atlasgeneticsoncology.org/gene/51113/wipf1
