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WIPF2 (WAS/WASL interacting protein family member 2)

Identity

Alias (NCBI)WICH
WIRE
HGNC (Hugo) WIPF2
HGNC Alias symbWICH
WIRE
HGNC Previous nameWAS/WASL interacting protein family, member 2
LocusID (NCBI) 147179
Atlas_Id 54783
Location 17q21.2  [Link to chromosome band 17q21]
Location_base_pair Starts at 40219304 and ends at 40284136 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
A2M (12p13.31) / WIPF2 (17q21.1)AKAP1 (17q22) / WIPF2 (17q21.1)MSI2 (17q22) / WIPF2 (17q21.1)
RARA (17q21.2) / WIPF2 (17q21.1)SYT7 (11q12.2) / WIPF2 (17q21.1)WIPF2 (17q21.1) / CDC42EP4 (17q25.1)
WIPF2 (17q21.1) / DSP (6p24.3)WIPF2 (17q21.1) / ERBB2 (17q12)WIPF2 (17q21.1) / EZH1 (17q21.2)
WIPF2 (17q21.1) / IL2RB (22q12.3)WIPF2 (17q21.1) / LRRC3C (17q12)WIPF2 (17q21.1) / MSL1 (17q21.1)
WIPF2 (17q21.1) / PSMD11 (17q11.2)WIPF2 (17q21.1) / RAPGEFL1 (17q21.1)WIPF2 (17q21.1) / SEZ6 (17q11.2)
WIPF2 (17q21.1) / USP32 (17q23.1)WIPF2 (17q21.1) / WIPF2 (17q21.1)AKAP1 17q22 / WIPF2 17q21.1
MSI2 17q22 / WIPF2 17q21.1RARA 17q21.2 / WIPF2 17q21.1WIPF2 17q21.1 / CDC42EP4 17q25.1
WIPF2 17q21.1 / EZH1 17q21.2WIPF2 17q21.1 / IL2RB 22q12.3WIPF2 17q21.1 / LRRC3C 17q12
WIPF2 17q21.1 / MSL1 17q21.1WIPF2 17q21.1 / PSMD11 17q11.2WIPF2 17q21.1 / RAPGEFL1 17q21.1
WIPF2 17q21.1 / SEZ6 17q11.2WIPF2 17q21.1 / USP32 17q23.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)WIPF2   30923
Cards
Entrez_Gene (NCBI)WIPF2    WAS/WASL interacting protein family member 2
AliasesWICH; WIRE
GeneCards (Weizmann)WIPF2
Ensembl hg19 (Hinxton)ENSG00000171475 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171475 [Gene_View]  ENSG00000171475 [Sequence]  chr17:40219304-40284136 [Contig_View]  WIPF2 [Vega]
ICGC DataPortalENSG00000171475
TCGA cBioPortalWIPF2
AceView (NCBI)WIPF2
Genatlas (Paris)WIPF2
SOURCE (Princeton)WIPF2
Genetics Home Reference (NIH)WIPF2
Genomic and cartography
GoldenPath hg38 (UCSC)WIPF2  -     chr17:40219304-40284136 +  17q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WIPF2  -     17q21.2   [Description]    (hg19-Feb_2009)
GoldenPathWIPF2 - 17q21.2 [CytoView hg19]  WIPF2 - 17q21.2 [CytoView hg38]
ImmunoBaseENSG00000171475
Genome Data Viewer NCBIWIPF2 [Mapview hg19]  
OMIM609692   
Gene and transcription
Genbank (Entrez)AB043786 AF370396 AJ431177 AK026913 AK055025
RefSeq transcript (Entrez)NM_133264
Consensus coding sequences : CCDS (NCBI)WIPF2
Gene ExpressionWIPF2 [ NCBI-GEO ]   WIPF2 [ EBI - ARRAY_EXPRESS ]   WIPF2 [ SEEK ]   WIPF2 [ MEM ]
Gene Expression Viewer (FireBrowse)WIPF2 [ Firebrowse - Broad ]
GenevisibleExpression of WIPF2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)147179
GTEX Portal (Tissue expression)WIPF2
Human Protein AtlasENSG00000171475-WIPF2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TF74   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TF74  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TF74
PhosPhoSitePlusQ8TF74
Domaine pattern : Prosite (Expaxy)WH2 (PS51082)   
Domains : Interpro (EBI)WH2_dom    WIPF2   
Domain families : Pfam (Sanger)WH2 (PF02205)   
Domain families : Pfam (NCBI)pfam02205   
Domain families : Smart (EMBL)WH2 (SM00246)  
Conserved Domain (NCBI)WIPF2
SuperfamilyQ8TF74
AlphaFold pdb e-kbQ8TF74   
Human Protein Atlas [tissue]ENSG00000171475-WIPF2 [tissue]
HPRD18304
Protein Interaction databases
DIP (DOE-UCLA)Q8TF74
IntAct (EBI)Q8TF74
BioGRIDWIPF2
STRING (EMBL)WIPF2
ZODIACWIPF2
Ontologies - Pathways
QuickGOQ8TF74
Ontology : AmiGOactin binding  protein binding  nucleoplasm  cytosol  actin filament  plasma membrane  actin filament-based movement  Fc-gamma receptor signaling pathway involved in phagocytosis  
Ontology : EGO-EBIactin binding  protein binding  nucleoplasm  cytosol  actin filament  plasma membrane  actin filament-based movement  Fc-gamma receptor signaling pathway involved in phagocytosis  
NDEx NetworkWIPF2
Atlas of Cancer Signalling NetworkWIPF2
Wikipedia pathwaysWIPF2
Orthology - Evolution
OrthoDB147179
GeneTree (enSembl)ENSG00000171475
Phylogenetic Trees/Animal Genes : TreeFamWIPF2
Homologs : HomoloGeneWIPF2
Homology/Alignments : Family Browser (UCSC)WIPF2
Gene fusions - Rearrangements
Fusion : MitelmanAKAP1/WIPF2 [17q22/17q21.1]  
Fusion : MitelmanMSI2/WIPF2 [17q22/17q21.1]  
Fusion : MitelmanRARA/WIPF2 [17q21.2/17q21.1]  
Fusion : MitelmanWIPF2/CDC42EP4 [17q21.1/17q25.1]  
Fusion : MitelmanWIPF2/ERBB2 [17q21.1/17q12]  
Fusion : MitelmanWIPF2/EZH1 [17q21.1/17q21.2]  
Fusion : MitelmanWIPF2/IL2RB [17q21.1/22q12.3]  
Fusion : MitelmanWIPF2/LRRC3C [17q21.1/17q12]  
Fusion : MitelmanWIPF2/MSL1 [17q21.1/17q21.1]  
Fusion : MitelmanWIPF2/PSMD11 [17q21.1/17q11.2]  
Fusion : MitelmanWIPF2/RAPGEFL1 [17q21.1/17q21.1]  
Fusion : MitelmanWIPF2/SEZ6 [17q21.1/17q11.2]  
Fusion : MitelmanWIPF2/USP32 [17q21.1/17q23.1]  
Fusion Cancer (Beijing)A2M [12p13.31]  -  WIPF2 [17q21.1]  [FUSC002802]
Fusion : QuiverWIPF2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWIPF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WIPF2
dbVarWIPF2
ClinVarWIPF2
MonarchWIPF2
1000_GenomesWIPF2 
Exome Variant ServerWIPF2
GNOMAD BrowserENSG00000171475
Varsome BrowserWIPF2
ACMGWIPF2 variants
VarityQ8TF74
Genomic Variants (DGV)WIPF2 [DGVbeta]
DECIPHERWIPF2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWIPF2 
Mutations
ICGC Data PortalWIPF2 
TCGA Data PortalWIPF2 
Broad Tumor PortalWIPF2
OASIS PortalWIPF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWIPF2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DWIPF2
Mutations and Diseases : HGMDWIPF2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaWIPF2
DgiDB (Drug Gene Interaction Database)WIPF2
DoCM (Curated mutations)WIPF2
CIViC (Clinical Interpretations of Variants in Cancer)WIPF2
Cancer3DWIPF2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609692   
Orphanet
DisGeNETWIPF2
MedgenWIPF2
Genetic Testing Registry WIPF2
NextProtQ8TF74 [Medical]
GENETestsWIPF2
Target ValidationWIPF2
Huge Navigator WIPF2 [HugePedia]
ClinGenWIPF2
Clinical trials, drugs, therapy
MyCancerGenomeWIPF2
Protein Interactions : CTDWIPF2
Pharm GKB GenePA162409210
PharosQ8TF74
Clinical trialWIPF2
Miscellaneous
canSAR (ICR)WIPF2
HarmonizomeWIPF2
DataMed IndexWIPF2
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXWIPF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:38:23 CEST 2021

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